CAS Number1015-89-0
Synonymsphenanthridone; 6-phenanthridinol; phenanthridin-6(5H)-one; EINECS 213-804-3; phenanthridin-6-ol; 6-(5H)-Phenanthridinone; MFCD00004988; 6-Hydroxyphenanthridine; 5,6-dihydrophenanthridin-6-one; 6(5H)-Phenanthridinone; 6(5H)-Phenanthridone; 5H-phenanthridin-6-one
Molecular FormulaC13H9NO
Molecular Weight195.22
Purity98.00%
Density1.2±0.1 g/cm3
Boiling Point274.8±7.0 °C at 760 mmHg
Melting Point290-292 °C (lit.)
Appearancepowder
EINECS213-804-3
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1015-89-0 |
| Catalog No. | 2A-9025944 |
| Chinese Name | 6(5H)-菲啶酮 |
| Synonyms | phenanthridone; 6-phenanthridinol; phenanthridin-6(5H)-one; EINECS 213-804-3; phenanthridin-6-ol; 6-(5H)-Phenanthridinone; MFCD00004988; 6-Hydroxyphenanthridine; 5,6-dihydrophenanthridin-6-one; 6(5H)-Phenanthridinone; 6(5H)-Phenanthridone; 5H-phenanthridin-6-one |
| Molecular Formula | C13H9NO |
| Molecular Weight | 195.22 |
| Purity | 98.00 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 274.8±7.0 °C at 760 mmHg |
| Melting Point | 290-292 °C (lit.) |
| Appearance | powder |
| Storage Condition | Keep container sealed and store in a cool, dry pla |
| Application | 6(5H)-Phenanthridinone is a potent PARP-1 inhibitor and immunomodulator. 6(5H)-Phenanthridinone inhibits cell proliferation and can be used in cancer research. |
| EINECS | 213-804-3 |
| HTC | 2933990090 |
| PubChem ID | 24858050 |
| MDL Number | MFCD00004988 |
| SMILES | O=C1Nc2ccccc2-c3ccccc13 |
| InChI | 1S/C13H9NO/c15-13-11-7-2-1-5-9(11)10-6-3-4-8-12(10)14-13/h1-8H,(H,14,15) |
| InChI Key | RZFVLEJOHSLEFR-UHFFFAOYSA-N |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Hazard Symbols | transportation |
| MSDS | msds/25944_1_1015_89_0.pdf |
| Bioactivity | 6(5H)-Phenanthridinone is a potent PARP-1 inhibitor and immunomodulator. 6(5H)-Phenanthridinone inhibits cell proliferation and can be used in cancer research[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Epigenetics >> PARP Research Areas >> Inflammation/Immunology Signaling Pathways >> Cell Cycle/DNA Damage >> PARP References [1]. Weltin D, et al. Immunosuppressive activities of 6(5H)-phenanthridinone, a new poly(ADP-ribose)polymerase inhibitor. Int J Immunopharmacol. 1995 Apr;17(4):265-71. Chemical & Physical Properties Density 1.2±0.1 g/cm3 Boiling Point 274.8±7.0 °C at 760 mmHg Melting Point 290-292 °C(lit.) Molecular Formula C13H9NO Molecular Weight 195.22 Flash Point 158.7±3.1 °C Exact Mass 195.068420 PSA 32.86000 LogP 2.81 Vapour Pressure 0.0±0.6 mmHg at 25°C Index of Refraction 1.642 InChIKey RZFVLEJOHSLEFR-UHFFFAOYSA-N SMILES O=c1[nH]c2ccccc2c2ccccc12 Storage condition 2-8°C |
| Use of | 6(5H)-Phenanthridinone is a potent PARP-1 inhibitor and immunomodulator. 6(5H)-Phenanthridinone inhibits cell proliferation and can be used in cancer research[1]. Properties Articles27 Name phenanthridone Synonym More Synonyms Phenanthridin-6(5H)-one Biological Activity Description 6(5H)-Phenanthridinone is a potent PARP-1 inhibitor and immunomodulator. 6(5H)-Phenanthridinone inhibits cell proliferation and can be used in cancer research[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Epigenetics >> PARP Research Areas >> Inflammation/Immunology Signaling Pathways >> Cell Cycle/DNA Damage >> PARP References [1]. Weltin D, et al. Immunosuppressive activities of 6(5H)-phenanthridinone, a new poly(ADP-ribose)polymerase inhibitor. Int J Immunopharmacol. 1995 Apr;17(4):265-71. Chemical & Physical Properties Molecular Formula C13H9NO Exact Mass 195.068420 PSA 32.86000 Index of Refraction 1.642 InChIKey RZFVLEJOHSLEFR-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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