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Lincomycin hydrochloride structure, CAS 859-18-7

Lincomycin hydrochloride

CAS Number859-18-7

SynonymsFrademicina; Lincorex; Lintamycin; Lincomycin (hydrochloride); Lyncomycin,HCl; EINECS 212-726-7; Lincolnensin Hydrochloride; Lizpion; Lincocin; Lincomycin hydrochloride; Pelancocin; MFCD00058237; LINCOMYCIN HCL; Lincogap; Luniamycin

Molecular FormulaC18H35ClN2O6S

Molecular Weight443.00

Purity96.0-102.0 (HPLC)%

Density

Boiling Point646.8ºC at 760 mmHg

Melting Point156-158ºC

Flash Point

Appearancepowder or crystals

EINECS212-726-7

MSDSChineseEnglish

Symboltransportation

Signal WordWarning

Cat. No.: 2A-0200176 Purity: 96.0-102.0 (HPLC)%
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Quality Control of [ 859-18-7 ] Purity: 96.0-102.0 (HPLC)% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number859-18-7
Catalog No.2A-0200176
Chinese Name盐酸林可霉素
SynonymsFrademicina; Lincorex; Lintamycin; Lincomycin (hydrochloride); Lyncomycin,HCl; EINECS 212-726-7; Lincolnensin Hydrochloride; Lizpion; Lincocin; Lincomycin hydrochloride; Pelancocin; MFCD00058237; LINCOMYCIN HCL; Lincogap; Luniamycin
Molecular FormulaC18H35ClN2O6S
Molecular Weight443.00
Purity96.0-102.0 (HPLC)
Boiling Point646.8ºC at 760 mmHg
Melting Point156-158ºC
Appearancepowder or crystals
Water SolubilityH2O: 50 mg/mL, clear, colorless | Soluble in water
Storage ConditionStore airtight at 2-8°C
ApplicationLincomycin (U10149A) hydrochloride is an antibiotic produced by Streptomyces lincomycin.
EINECS212-726-7
HTC2941904000
PubChem ID329759714
MDL NumberMFCD00083647
SMILESCl.CCC[C@@H]1C[C@H](N(C)C1)C(=O)N[C@H]([C@@H](C)O)[C@H]2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O
InChI1S/C18H34N2O6S.ClH/c1-5-6-10-7-11(20(3)8-10)17(25)19-12(9(2)21)16-14(23)13(22)15(24)18(26-16)27-4;/h9-16,18,21-24H,5-8H2,1-4H3,(H,19,25);1H/t9-,10-,11+,12-,13+,14-,15-,16-,18-;/m1./s1
InChI KeyPOUMFISTNHIPTI-BOMBIWCESA-N
Beilstein/REAXYS4171650
NACRES CodeNA.85
UNSPSC51284507
Hazard Symbolstransportation
MSDSmsds/25426_1_859_18_7.pdf
BioactivityLincomycin Hydrochloride(U10149A) is an antibiotic produced by Streptomyces lincolnensis var. lincolnensis.Target: AntibacterialLincomycin hydrochloride is a systemic antibiotic, which is active against most common gram positive bacteria. It has proved to be excellent for infectious diseases like acne, anthrax, pneumonia, and also for the treatment of furunculosis, carbuncles, impetigo, burns and wounds, carrying to gram positive bacteria. Lincomycin hydrochloride inhibits cell growth and microbial protein synthesis, by interacting strongly and specifically with the 50S ribosomal subunit, at mutually related sites [1-3]. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. Griaznova, N.S., et al., [Effect of lincomycin and other protein synthesis inhibitors on the metabolism of Actinomyces roseolus, a producer of lincomycin]. Antibiotiki, 1980. 25(4): p. 250-6. [2]. Hummel, H., W. Piepersberg, and A. Bock, Analysis of lincomycin resistance mutations in Escherichia coli. Mol Gen Genet, 1979. 169(3): p. 345-7. [3]. Champney, W.S. and C.L. Tober, Specific inhibition of 50S ribosomal subunit formation in Staphylococcus aureus cells by 16-membered macrolide, lincosamide, and streptogramin B antibiotics. Curr Microbiol, 2000. 41(2): p. 126-35. Chemical & Physical Properties Boiling Point 646.8ºC at 760 mmHg Melting Point 156-158ºC Molecular Formula C18H35ClN2O6S Molecular Weight 442.998 Flash Point 345ºC Exact Mass 442.190430 PSA 147.79000 LogP 0.27380 InChIKey POUMFISTNHIPTI-UHFFFAOYSA-N SMILES CCCC1CC(C(=O)NC(C(C)O)C2OC(SC)C(O)C(O)C2O)N(C)C1.Cl Storage condition 2-8°C Water Solubility H2O: 50 mg/mL, clear, colorless | Soluble in water.
Use ofLincomycin Hydrochloride(U10149A) is an antibiotic produced by Streptomyces lincolnensis var. lincolnensis.Target: AntibacterialLincomycin hydrochloride is a systemic antibiotic, which is active against most common gram positive bacteria. It has proved to be excellent for infectious diseases like acne, anthrax, pneumonia, and also for the treatment of furunculosis, carbuncles, impetigo, burns and wounds, carrying to gram positive bacteria. Lincomycin hydrochloride inhibits cell growth and microbial protein synthesis, by interacting strongly and specifically with the 50S ribosomal subunit, at mutually related sites [1-3]. Properties Articles40 Name Lincomycin hydrochloride Synonym More Synonyms Lincomycin hydrochloride Biological Activity Description Lincomycin Hydrochloride(U10149A) is an antibiotic produced by Streptomyces lincolnensis var. lincolnensis.Target: AntibacterialLincomycin hydrochloride is a systemic antibiotic, which is active against most common gram positive bacteria. It has proved to be excellent for infectious diseases like acne, anthrax, pneumonia, and also for the treatment of furunculosis, carbuncles, impetigo, burns and wounds, carrying to gram positive bacteria. Lincomycin hydrochloride inhibits cell growth and microbial protein synthesis, by interacting strongly and specifically with the 50S ribosomal subunit, at mutually related sites [1-3]. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. Griaznova, N.S., et al., [Effect of lincomycin and other protein synthesis inhibitors on the metabolism of Actinomyces roseolus, a producer of lincomycin]. Antibiotiki, 1980. 25(4): p. 250-6. [2]. Hummel, H., W. Piepersberg, and A. Bock, Analysis of lincomycin resistance mutations in Escherichia coli. Mol Gen Genet, 1979. 169(3): p. 345-7. [3]. Champney, W.S. and C.L. Tober, Specific inhibition of 50S ribosomal subunit formation in Staphylococcus aureus cells by 16-membered macrolide, lincosamide, and streptogramin B antibiotics. Curr Microbiol, 2000. 41(2): p. 126-35. Chemical & Physical Properties Exact Mass 442.190430 PSA 147.79000 LogP 0.27380 InChIKey POUMFISTNHIPTI-UHFFFAOYSA-N
Transport InfoShipping Name: UN
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available
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