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2-Aminoquinoline structure, CAS 580-22-3

2-Aminoquinoline

CAS Number580-22-3

SynonymsMFCD00038079; 2(1H)-Quinolinimine; 2-Aminoquindine; EINECS 209-458-8; 2-Quinolinamine; iminoquinoline; quinolin-2-amine

Molecular FormulaC9H8N2

Molecular Weight169.18

Purity98%

Density1.2±0.1 g/cm3

Boiling Point304.9±15.0 °C at 760 mmHg

Melting Point125 °C

Flash Point

Appearancesolid

EINECS209-458-8

MSDSChineseEnglish

SymbolTransport

Signal WordWarning

Cat. No.: 2A-9002471 Purity: 98%
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Quality Control of [ 580-22-3 ] Purity: 98% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number580-22-3
Catalog No.2A-9002471
Chinese Name2-氨基喹啉
SynonymsMFCD00038079; 2(1H)-Quinolinimine; 2-Aminoquindine; EINECS 209-458-8; 2-Quinolinamine; iminoquinoline; quinolin-2-amine
Molecular FormulaC9H8N2
Molecular Weight169.18
Purity98
Density1.2±0.1 g/cm3
Boiling Point304.9±15.0 °C at 760 mmHg
Melting Point125 °C
Appearancesolid
Water Solubilitysoluble
Storage ConditionThis product should be sealed and stored away from
Application2-Aminoquinoline is a promising bioavailable nNOS inhibitor, but its inhibition rate on human nNOS is low, its selectivity for human eNOS is low, and it has obvious combination with other central nerv
EINECS209-458-8
HTC2933499090
PubChem ID329790654
MDL NumberMFCD00662531
SMILESNc1nc2ccccc2cc1C#N
InChI1S/C10H7N3/c11-6-8-5-7-3-1-2-4-9(7)13-10(8)12/h1-5H,(H2,12,13)
InChI KeyRANOMAHFIQOQIG-UHFFFAOYSA-N
NACRES CodeNA.21
UNSPSC12352200
Hazard SymbolsTransport
Risk CodesR20/21/22;R36/37/38
Safety DescriptionS26;S36/37/39
MSDSmsds/2471_1_580_22_3.pdf
Bioactivity2-Aminoquinoline is a promising compound as bioavailable nNOS inhibitor but suffers from low human nNOS inhibition, low selectivity versus human eNOS, and significant binding to other CNS targets. 2-Aminoquinoline has the potential for the research of antineurodegenerative agents[1]. Related Catalog Signaling Pathways >> Immunology/Inflammation >> NO Synthase Research Areas >> Neurological Disease References [1]. Pensa AV, et al. Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors. J Med Chem. 2017;60(16):7146-7165. Chemical & Physical Properties Density 1.2±0.1 g/cm3 Boiling Point 304.9±15.0 °C at 760 mmHg Melting Point 125 °C Molecular Formula C9H8N2 Molecular Weight 144.17 Flash Point 163.6±7.6 °C Exact Mass 144.068741 PSA 38.91000 LogP 1.73 Vapour Pressure 0.0±0.6 mmHg at 25°C Index of Refraction 1.708 InChIKey GCMNJUJAKQGROZ-UHFFFAOYSA-N SMILES Nc1ccc2ccccc2n1 Water Solubility soluble
Use of2-Aminoquinoline is a promising compound as bioavailable nNOS inhibitor but suffers from low human nNOS inhibition, low selectivity versus human eNOS, and significant binding to other CNS targets. 2-Aminoquinoline has the potential for the research of antineurodegenerative agents[1]. Properties Name 2-Aminoquinoline Synonym More Synonyms 2-Aminoquinoline Biological Activity Description 2-Aminoquinoline is a promising compound as bioavailable nNOS inhibitor but suffers from low human nNOS inhibition, low selectivity versus human eNOS, and significant binding to other CNS targets. 2-Aminoquinoline has the potential for the research of antineurodegenerative agents[1]. Related Catalog Signaling Pathways >> Immunology/Inflammation >> NO Synthase Research Areas >> Neurological Disease References [1]. Pensa AV, et al. Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors. J Med Chem. 2017;60(16):7146-7165. Chemical & Physical Properties Molecular Formula C9H8N2 Exact Mass 144.068741 PSA 38.91000 Index of Refraction 1.708 InChIKey GCMNJUJAKQGROZ-UHFFFAOYSA-N Water Solubility soluble
Tax Rebate13.0%
SupervisionNone. MFN tariff: 6.5%. Ordinary tariff: 20.0%
Transport InfoProduct name: Purity: 0.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: No dangerous goods IMDG Code: No dangerous goods International Air Transport Dangerous Regulations: No dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special precautions for users No data available
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