
CAS Number605-23-2
SynonymsThymine arabinofuranoside; 1-(β-D-Arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; spongothymidine; thymine arabinoside; ARABINOFURANOSYL-5-METHYLURACIL; EINECS 210-083-7; MFCD00065474; 1-(β-D-arabinofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-[3,4-Dihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidindion; 5-Methyl-1-pentofuranosyl-2,4(1H,3H)-pyrimidinedione; ARA-T; 5-Methyl-1-pentofuranosylpyrimidine-2,4(1H,3H)-dione; 1-[3,4-Dihydroxy-5-(hydroxyméthyl)tétrahydro-2-furanyl]-5-méthyl-2,4(1H,3H)-pyrimidinedione; 1-B-D-Arabinofuranosylthymine; spongothymidin; Arabinofuranosylthymine; 1-[3,4-Dihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione; Thymine 1-beta-D-arabinofuranoside; 1-β-D-Arabinofuranosylthymine; arabinosylthymi
Molecular FormulaC10H14N2O6
Molecular Weight258.23
Purity≥99%
Density1.6±0.1 g/cm3
Appearancepowder
EINECS210-083-7
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 605-23-2 |
| Catalog No. | 2A-9024018 |
| Chinese Name | 阿糖胸苷 |
| Synonyms | Thymine arabinofuranoside; 1-(β-D-Arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; spongothymidine; thymine arabinoside; ARABINOFURANOSYL-5-METHYLURACIL; EINECS 210-083-7; MFCD00065474; 1-(β-D-arabinofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-[3,4-Dihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidindion; 5-Methyl-1-pentofuranosyl-2,4(1H,3H)-pyrimidinedione; ARA-T; 5-Methyl-1-pentofuranosylpyrimidine-2,4(1H,3H)-dione; 1-[3,4-Dihydroxy-5-(hydroxyméthyl)tétrahydro-2-furanyl]-5-méthyl-2,4(1H,3H)-pyrimidinedione; 1-B-D-Arabinofuranosylthymine; spongothymidin; Arabinofuranosylthymine; 1-[3,4-Dihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione; Thymine 1-beta-D-arabinofuranoside; 1-β-D-Arabinofuranosylthymine; arabinosylthymi |
| Molecular Formula | C10H14N2O6 |
| Molecular Weight | 258.23 |
| Purity | ≥99 |
| Density | 1.6±0.1 g/cm3 |
| Appearance | powder |
| Storage Condition | Storage: Seal the container and store it in a seal |
| Application | Thymine 1-β-D-arabinofuranoside is a purine nucleoside analog. Purine nucleoside analogues have broad antitumor activity and target indolent lymphoid malignancies. The anti-cancer mechanism in this pr |
| EINECS | 210-083-7 |
| PubChem ID | 24900167 |
| MDL Number | MFCD00065474 |
| SMILES | CC1=CN(C2OC(CO)C(O)C2O)C(=O)NC1=O |
| InChI | 1S/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17) |
| InChI Key | DWRXFEITVBNRMK-UHFFFAOYSA-N |
| NACRES Code | NA.51 |
| UNSPSC | 41106305 |
| Hazard Symbols | transportation |
| MSDS | msds/24018_1_605_23_2.pdf |
| Bioactivity | Thymine 1-β-D-arabinofuranoside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Related Catalog Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others References [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. Chemical & Physical Properties Density 1.6±0.1 g/cm3 Molecular Formula C10H14N2O6 Molecular Weight 258.23 Exact Mass 258.085175 PSA 124.78000 LogP -1.02 Index of Refraction 1.619 InChIKey DWRXFEITVBNRMK-JAGXHNFQSA-N SMILES Cc1cn(C2OC(CO)C(O)C2O)c(=O)[nH]c1=O Storage condition 2-8°C |
| Use of | Thymine 1-β-D-arabinofuranoside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Properties Articles64 Name 1-.β.-D-Arabinofuranosylthymine Synonym More Synonyms Thymine-beta-D-arabinofuranoside Biological Activity Description Thymine 1-β-D-arabinofuranoside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Related Catalog Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others References [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. Chemical & Physical Properties Molecular Formula C10H14N2O6 Exact Mass 258.085175 PSA 124.78000 LogP -1.02 Index of Refraction 1.619 InChIKey DWRXFEITVBNRMK-JAGXHNFQSA-N |
| Transport Info | Product name: Purity: 99.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
| Related Products in Heterocyclic Building Blocks | ||
|---|---|---|
| 3-Amino-5-methylpyridine-2-carbonitrile | 1001635-30-8 | 2A-9023409 |
| 5-AMINO-1H-INDAZOLE-3-CARBONITRILE | 89939-59-3 | 2A-9023580 |
| 6H-Pyrazolo[3,4-c]pyridine-3,6-dicarboxylic acid, 1,4,5,7-tetrahydro-, 6-(1,1-dimethylethyl) ester | 821785-76-6 | 2A-9023619 |
| 5-Hydroxyquinoline | 578-67-6 | 2A-9023715 |
| 4-Pyrimidinecarbonitrile, 2-amino- (9CI) | 36314-98-4 | 2A-9023755 |
| 2,3-Pyridinedicarboxylic acid dimethyl ester | 605-38-9 | 2A-9024019 |
| 4-Methoxyquinoline | 607-31-8 | 2A-9024044 |
| 5-Nitroquinoline | 607-34-1 | 2A-9024046 |
| 8-Nitroquinoline | 607-35-2 | 2A-9024047 |
| 4-Hydroxy-2-methylquinoline | 607-67-0 | 2A-9024050 |
| Browse all Heterocyclic Building Blocks products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA