CAS Number557-04-0
SynonymsMAGNESIUM DISTEARATE; Magnesium stearate; synpro 90; MFCD00036391; Stearic acid, magnesium salt; MAGNESIUM STEARATE (E-470B, F.C.C.) ADITIO; EINECS 209-150-3; Octadecanoic acid, magnesium salt; stearic acid magnesium salt; Octadecanoic acid, magnesium salt (2:1); stearatedemagnesium; MAGENSIUM STEARATE; MAGNESIUMSTEARATE; MEGNESIUM STEATATE; MAGNESIUMSTEARATEBP; Magnesium dioctadecanoate; Microcrystalline cellulose use as the oral steroid filler; Dibasic magnesium stearate; MAGNESIUM STEARATE API; magnesiumdistearate; Synpro Magnesium Stearate 90; OCTADECANOIC ACID MAGNESIUM SALT; stearate magnesium; Magnesiumdistearat; MAGNESIUM STEARATE NF; MAGNESIUM OCTADECANOATE; magnesium sterate; stearic acid,magnesium stearate; Dolomol; Magnesiumstearat
Molecular FormulaC36H70MgO4
Molecular Weight591.24
Purity98.00%
Density1.028g/cm3
Boiling Point359.4ºC at 760mmHg
Melting Point140 °C
Appearancefine powder
EINECS209-150-3
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 557-04-0 |
| Catalog No. | 2A-0202123 |
| Chinese Name | 硬脂酸镁 |
| Synonyms | MAGNESIUM DISTEARATE; Magnesium stearate; synpro 90; MFCD00036391; Stearic acid, magnesium salt; MAGNESIUM STEARATE (E-470B, F.C.C.) ADITIO; EINECS 209-150-3; Octadecanoic acid, magnesium salt; stearic acid magnesium salt; Octadecanoic acid, magnesium salt (2:1); stearatedemagnesium; MAGENSIUM STEARATE; MAGNESIUMSTEARATE; MEGNESIUM STEATATE; MAGNESIUMSTEARATEBP; Magnesium dioctadecanoate; Microcrystalline cellulose use as the oral steroid filler; Dibasic magnesium stearate; MAGNESIUM STEARATE API; magnesiumdistearate; Synpro Magnesium Stearate 90; OCTADECANOIC ACID MAGNESIUM SALT; stearate magnesium; Magnesiumdistearat; MAGNESIUM STEARATE NF; MAGNESIUM OCTADECANOATE; magnesium sterate; stearic acid,magnesium stearate; Dolomol; Magnesiumstearat |
| Molecular Formula | C36H70MgO4 |
| Molecular Weight | 591.24 |
| Purity | 98.00 |
| Density | 1.028g/cm3 |
| Boiling Point | 359.4ºC at 760mmHg |
| Melting Point | 140 °C |
| Appearance | fine powder |
| Water Solubility | Insoluble |
| Storage Condition | 1. Packed in lined plastic bags, outer woven bags |
| Application | Magnesium stearate is a commonly used pharmaceutical lubricant. However, magnesium stearate can adversely affect the bonding between particles. Magnesium stearate can be used as an excipient, such as |
| EINECS | 209-150-3 |
| HTC | 29157030 |
| MDL Number | MFCD00036391 |
| SMILES | [Mg+2].[O-]C(=O)CCCCCCCCCCCCCCCCC.[O-]C(=O)CCCCCCCCCCCCCCCCC |
| InChI | 1S/2C18H36O2.Mg/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2*2-17H2,1H3,(H,19,20);/q;;+2/p-2 |
| InChI Key | HQKMJHAJHXVSDF-UHFFFAOYSA-L |
| UNSPSC | 12352107 |
| Hazard Symbols | Transport |
| Risk Codes | R36/37/38 |
| Safety Description | S26;S37/39 |
| MSDS | msds/22901_1_557_04_0.pdf |
| Bioactivity | Magnesium stearate is a commonly used pharmaceutical lubricant. But Magnesium stearate leads to an adverse effect on bonding between particles. Magnesium stearate can be used as an excipient, such as lubricant. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Zuurman K, et al. Effect of magnesium stearate on bonding and porosity expansion of tablets produced from materials with different consolidation properties[J]. International journal of pharmaceutics, 1999, 179(1): 107-115. [2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99. Chemical & Physical Properties Density 1.028g/cm3 Boiling Point 359.4ºC at 760mmHg Melting Point 200 °C(lit.) Molecular Formula C36H70MgO4 Molecular Weight 591.24 Flash Point 162.4ºC Exact Mass 590.512451 PSA 52.60000 LogP 12.50830 Index of Refraction 1.45 (25ºC) Storage condition Store at RT. Stability Stable. Incompatible with strong oxidizing agents. Water Solubility Insoluble |
| Use of | Magnesium stearate is a commonly used pharmaceutical lubricant. But Magnesium stearate leads to an adverse effect on bonding between particles. Magnesium stearate can be used as an excipient, such as lubricant. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2]. Properties Articles98 Name magnesium distearate Synonym More Synonyms Magnesium stearate Biological Activity Description Magnesium stearate is a commonly used pharmaceutical lubricant. But Magnesium stearate leads to an adverse effect on bonding between particles. Magnesium stearate can be used as an excipient, such as lubricant. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Zuurman K, et al. Effect of magnesium stearate on bonding and porosity expansion of tablets produced from materials with different consolidation properties[J]. International journal of pharmaceutics, 1999, 179(1): 107-115. [2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99. Chemical & Physical Properties Molecular Formula C36H70MgO4 Exact Mass 590.512451 PSA 52.60000 LogP 12.50830 Index of Refraction 1.45 (25ºC) Storage condition Store at RT. Stability Stable. Incompatible with strong oxidizing agents. Water Solubility Insoluble |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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