CAS Number537-73-5
Synonyms3'-hydroxy-4'-methoxy cinnamic acid; Hesperitinic acid; trans-Isoferulic acid; RARECHEM BK HW 0093; trans-3-hydroxy-4-methoxycinnamic acid; 3-Hydroxy-4-MethoxycinnaMic Acid; 3-(3-Hydroxy-4-methoxyphenyl)acrylic acid; 3-Hydroxy-4-methoxycinnamic; Isoferulic acid; HESPERETINIC ACID; Isoferulate; MFCD00004391; EINECS 208-676-0; Isoferulic; Caffeic acid 4-methyl ether; (2E)-3-(3-Hydroxy-4-methoxyphenyl)acrylic acid; 3-(3-Hydroxy-4-methoxyphenyl)-2-propenoic acid; Hesperetic acid; (2E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid; 3-hydroxy-4-methoxy-Cinnamic acid
Molecular FormulaHOC6H3(OCH3)CH=CHCO2H
Molecular Weight194.18
Purity97%
Density1.3±0.1 g/cm3
Boiling Point410.2±35.0 °C at 760 mmHg
Melting Point230 °C (dec.) (lit.)
Appearancesolid
EINECS208-676-0
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 537-73-5 |
| Catalog No. | 2A-9022694 |
| Chinese Name | 异阿魏酸 |
| Synonyms | 3'-hydroxy-4'-methoxy cinnamic acid; Hesperitinic acid; trans-Isoferulic acid; RARECHEM BK HW 0093; trans-3-hydroxy-4-methoxycinnamic acid; 3-Hydroxy-4-MethoxycinnaMic Acid; 3-(3-Hydroxy-4-methoxyphenyl)acrylic acid; 3-Hydroxy-4-methoxycinnamic; Isoferulic acid; HESPERETINIC ACID; Isoferulate; MFCD00004391; EINECS 208-676-0; Isoferulic; Caffeic acid 4-methyl ether; (2E)-3-(3-Hydroxy-4-methoxyphenyl)acrylic acid; 3-(3-Hydroxy-4-methoxyphenyl)-2-propenoic acid; Hesperetic acid; (2E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid; 3-hydroxy-4-methoxy-Cinnamic acid |
| Molecular Formula | HOC6H3(OCH3)CH=CHCO2H |
| Molecular Weight | 194.18 |
| Purity | 97 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 410.2±35.0 °C at 760 mmHg |
| Melting Point | 230 °C (dec.) (lit.) |
| Appearance | solid |
| Storage Condition | Store sealed and placed in a ventilated, dry place |
| Application | 3-Hydroxy-4-methoxycinnamic acid (Isoferulic acid) is a cinnamic acid derivative with antidiabetic activity. 3-Hydroxy-4-methoxycinnamic acid binds to and activates α1-adrenergic receptors (IC50=1.4 μ |
| EINECS | 208-676-0 |
| HTC | 29189090 |
| PubChem ID | 24846591 |
| MDL Number | MFCD00004391 |
| SMILES | COc1ccc(\C=C\C(O)=O)cc1O |
| InChI | 1S/C10H10O4/c1-14-9-4-2-7(6-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)/b5-3+ |
| InChI Key | QURCVMIEKCOAJU-HWKANZROSA-N |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| MSDS | msds/22694_1_537_73_5.pdf |
| Bioactivity | 3-Hydroxy-4-methoxycinnamic acid (Isoferulic acid) is a cinnamic acid derivative that has antidiabetic activity. 3-Hydroxy-4-methoxycinnamic acid binds to and activates α1-adrenergic receptors (IC50=1.4 µM) to enhance secretion of β-endorphin (EC50=52.2 nM) and increase glucose use. Related Catalog Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Metabolic Disease Natural Products >> Phenylpropanoids References [1]. Liu IM, et al. Mediation of beta-endorphin by isoferulic acid to lower plasma glucose in streptozotocin-induced diabetic rats. J Pharmacol Exp Ther. 2003 Dec;307(3):1196-204. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 410.2±35.0 °C at 760 mmHg Melting Point 230 °C (dec.)(lit.) Molecular Formula C10H10O4 Molecular Weight 194.184 Flash Point 167.6±19.4 °C Exact Mass 194.057907 PSA 66.76000 LogP 1.56 Vapour Pressure 0.0±1.0 mmHg at 25°C Index of Refraction 1.627 Storage condition -20?C Freezer |
| Use of | 3-Hydroxy-4-methoxycinnamic acid (Isoferulic acid) is a cinnamic acid derivative that has antidiabetic activity. 3-Hydroxy-4-methoxycinnamic acid binds to and activates α1-adrenergic receptors (IC50=1.4 µM) to enhance secretion of β-endorphin (EC50=52.2 nM) and increase glucose use. Properties Articles47 Name 3-Hydroxy-4-methoxycinnamic acid Synonym More Synonyms Isoferulic acid Biological Activity Description 3-Hydroxy-4-methoxycinnamic acid (Isoferulic acid) is a cinnamic acid derivative that has antidiabetic activity. 3-Hydroxy-4-methoxycinnamic acid binds to and activates α1-adrenergic receptors (IC50=1.4 µM) to enhance secretion of β-endorphin (EC50=52.2 nM) and increase glucose use. Related Catalog Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Metabolic Disease Natural Products >> Phenylpropanoids References [1]. Liu IM, et al. Mediation of beta-endorphin by isoferulic acid to lower plasma glucose in streptozotocin-induced diabetic rats. J Pharmacol Exp Ther. 2003 Dec;307(3):1196-204. Chemical & Physical Properties Molecular Formula C10H10O4 Exact Mass 194.057907 PSA 66.76000 Index of Refraction 1.627 Storage condition -20?C Freezer |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards 3-Hydroxy-4-methoxycinnamic acid Modification number: 5 Module 14. Shipping information UN number: not specified |
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