CAS Number529-53-3
Synonyms5,6,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one; 5,6,7,4'-tetrahydroxyflavone; 5,6,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 4',5,6,7-Tetrahydroxyflavanone; 6-Hydroxypelargidenon 1465; Scutellarein
Molecular FormulaC15H10O6
Molecular Weight286.24
Purity≥98 (HPLC)%
Density1.7±0.1 g/cm3
Boiling Point642.9±55.0 °C at 760 mmHg
Melting Point330ºC
Appearancepowder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 529-53-3 |
| Catalog No. | 2A-9022547 |
| Chinese Name | 野黄芩素 |
| Synonyms | 5,6,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one; 5,6,7,4'-tetrahydroxyflavone; 5,6,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 4',5,6,7-Tetrahydroxyflavanone; 6-Hydroxypelargidenon 1465; Scutellarein |
| Molecular Formula | C15H10O6 |
| Molecular Weight | 286.24 |
| Purity | ≥98 (HPLC) |
| Density | 1.7±0.1 g/cm3 |
| Boiling Point | 642.9±55.0 °C at 760 mmHg |
| Melting Point | 330ºC |
| Appearance | powder |
| Water Solubility | DMSO: soluble1mg/mL, clear, greenish-yellow |
| Storage Condition | 2-8°C |
| Application | Scutellarein is a natural flavonoid compound with anti-inflammatory effects. |
| HTC | 2914501900 |
| PubChem ID | 329824421 |
| MDL Number | MFCD00017692 |
| SMILES | Oc1ccc(cc1)C2=CC(=O)c3c(O)c(O)c(O)cc3O2 |
| InChI | 1S/C15H10O6/c16-8-3-1-7(2-4-8)11-5-9(17)13-12(21-11)6-10(18)14(19)15(13)20/h1-6,16,18-20H |
| InChI Key | JVXZRQGOGOXCEC-UHFFFAOYSA-N |
| NACRES Code | NA.25 |
| UNSPSC | 12352200 |
| Hazard Symbols | Transport |
| MSDS | msds/22547_1_529_53_3.pdf |
| Bioactivity | Scutellarin, a main active ingredient extracted from Erigeron breviscapus (Vant.) Hand-Mazz., has been wildly used to treat acute cerebral infarction and paralysis induced by cerebrovascular diseases. Related Catalog Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Src Research Areas >> Inflammation/Immunology Natural Products >> Flavonoids References [1]. Xiaoxuan Tian, et al. Delineation of Platelet Activation Pathway of Scutellarein Revealed Its Intracellular Target as Protein Kinase C. Biological and Pharmaceutical BulletinVol. 39 (2016) No. 2 p. 181-191 [2]. Sung NY, et al. Scutellarein Reduces Inflammatory Responses by Inhibiting Src Kinase Activity. Korean J Physiol Pharmacol. 2015 Sep;19(5):441-9. Chemical & Physical Properties Density 1.7±0.1 g/cm3 Boiling Point 642.9±55.0 °C at 760 mmHg Melting Point 330ºC Molecular Formula C15H10O6 Molecular Weight 286.236 Flash Point 249.9±25.0 °C Exact Mass 286.047729 PSA 111.13000 LogP 2.54 Appearance of Characters yellow Vapour Pressure 0.0±2.0 mmHg at 25°C Index of Refraction 1.768 InChIKey JVXZRQGOGOXCEC-UHFFFAOYSA-N SMILES O=c1cc(-c2ccc(O)cc2)oc2cc(O)c(O)c(O)c12 Storage condition 2-8°C Water Solubility DMSO: soluble1mg/mL, clear, greenish-yellow |
| Use of | Scutellarin, a main active ingredient extracted from Erigeron breviscapus (Vant.) Hand-Mazz., has been wildly used to treat acute cerebral infarction and paralysis induced by cerebrovascular diseases. Properties Articles29 Name Scutellarein Synonym More Synonyms Scutellarein Biological Activity Description Scutellarin, a main active ingredient extracted from Erigeron breviscapus (Vant.) Hand-Mazz., has been wildly used to treat acute cerebral infarction and paralysis induced by cerebrovascular diseases. Related Catalog Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Src Research Areas >> Inflammation/Immunology Natural Products >> Flavonoids References [1]. Xiaoxuan Tian, et al. Delineation of Platelet Activation Pathway of Scutellarein Revealed Its Intracellular Target as Protein Kinase C. Biological and Pharmaceutical BulletinVol. 39 (2016) No. 2 p. 181-191 [2]. Sung NY, et al. Scutellarein Reduces Inflammatory Responses by Inhibiting Src Kinase Activity. Korean J Physiol Pharmacol. 2015 Sep;19(5):441-9. Chemical & Physical Properties Molecular Formula C15H10O6 Exact Mass 286.047729 PSA 111.13000 Appearance of Characters yellow Index of Refraction 1.768 InChIKey JVXZRQGOGOXCEC-UHFFFAOYSA-N |
| Tax Rebate | 9.0% |
| Supervision | none |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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