CAS Number522-48-5
SynonymsMFCD00058029; 2-(1,2,3,4-tétrahydronaphtalén-1-yl)-4,5-dihydro-1H-imidazole chlorhydrate; 2-(1,2,3,4-Tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole hydrochloride (1:1); EINECS 208-329-3; Tetrahydrozoline hydrochloride; 2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole,hydrochloride; 2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole hydrochloride; 2-(1,2,3,4-Tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazolhydrochlorid; 2-(1,2,3,4-Tetrahydro-1-naphthalenyl)-4,5-dihydro-1H-imidazole hydrochloride (1:1); 1H-Imidazole, 4,5-dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-, hydrochloride (1:1); Tetrahydrozoline (hydrochloride)
Molecular FormulaC13H17ClN2
Molecular Weight236.74
Purity99.00%
Boiling Point393.5ºC at 760 mmHg
Melting Point197 °C
Appearanceoff-white solid
EINECS208-329-3
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 522-48-5 |
| Catalog No. | 2A-9022485 |
| Chinese Name | 盐酸四氢唑啉 |
| Synonyms | MFCD00058029; 2-(1,2,3,4-tétrahydronaphtalén-1-yl)-4,5-dihydro-1H-imidazole chlorhydrate; 2-(1,2,3,4-Tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole hydrochloride (1:1); EINECS 208-329-3; Tetrahydrozoline hydrochloride; 2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole,hydrochloride; 2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole hydrochloride; 2-(1,2,3,4-Tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazolhydrochlorid; 2-(1,2,3,4-Tetrahydro-1-naphthalenyl)-4,5-dihydro-1H-imidazole hydrochloride (1:1); 1H-Imidazole, 4,5-dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-, hydrochloride (1:1); Tetrahydrozoline (hydrochloride) |
| Molecular Formula | C13H17ClN2 |
| Molecular Weight | 236.74 |
| Purity | 99.00 |
| Boiling Point | 393.5ºC at 760 mmHg |
| Melting Point | 197 °C |
| Appearance | off-white solid |
| Storage Condition | Refrigerator |
| Application | Tetrahydrozoline hydrochloride is an alpha-adrenoceptor agonist. |
| EINECS | 208-329-3 |
| HTC | 2934999090 |
| MDL Number | MFCD00058029 |
| SMILES | Cl.C1CC(C2=NCCN2)c3ccccc3C1 |
| InChI | 1S/C13H16N2.ClH/c1-2-6-11-10(4-1)5-3-7-12(11)13-14-8-9-15-13;/h1-2,4,6,12H,3,5,7-9H2,(H,14,15);1H |
| InChI Key | BJORNXNYWNIWEY-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/22485_1_522_48_5.pdf |
| Bioactivity | Tetrahydrozoline (hydrochloride) is a α-adrenoceptor agonist. Target: α-adrenoceptorahydrozoline is an imidazoline derivative with alpha receptor agonist activity widely available in over-the-counter topical ocular and nasal formulations. More than 1,600 cases of oral exposures are reported to United States poison centers annually (1,2). Reports of significant toxicity from tetrahydrozoline ingestion are unusual but have occured primarily in small children after unintentional ingestion (3-63, 6) [1]. Related Catalog Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Cardiovascular Disease References [1]. Spiller, H. and J. Griffith, Prolonged cardiovascular effects after unintentional ingestion of tetrahydrozoline. Clin Toxicol (Phila), 2008. 46(2): p. 171-2. Chemical & Physical Properties Boiling Point 393.5ºC at 760 mmHg Melting Point 197 °C Molecular Formula C13H17ClN2 Molecular Weight 236.740 Flash Point 191.8ºC Exact Mass 236.108032 PSA 24.39000 LogP 2.67460 InChIKey BJORNXNYWNIWEY-UHFFFAOYSA-N SMILES Cl.c1ccc2c(c1)CCCC2C1=NCCN1 Storage condition Refrigerator |
| Use of | Properties Articles30 Name Tetrahydrozoline Hydrochloride Synonym More Synonyms Tetrahydrozoline hydrochloride Biological Activity Related Catalog Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Cardiovascular Disease References [1]. Spiller, H. and J. Griffith, Prolonged cardiovascular effects after unintentional ingestion of tetrahydrozoline. Clin Toxicol (Phila), 2008. 46(2): p. 171-2. Chemical & Physical Properties Exact Mass 236.108032 PSA 24.39000 LogP 2.67460 InChIKey BJORNXNYWNIWEY-UHFFFAOYSA-N Storage condition Refrigerator |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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