CAS Number516-05-2
SynonymsMethylmalonic acid; Methylpropanedioic acid; EINECS 208-219-5; 2-Methylmalonic acid; methyl-Propanedioic acid; 2-Methylpropanedioic acid; MFCD00002656; methyl-Malonic acid; 2-Methyl1-malonic acid; Methylmalonate
Molecular FormulaCH3CH(CO2H)2
Molecular Weight118.09
Purity99%
Density1.45
Boiling Point334.4±25.0 °C at 760 mmHg
Melting Point128-130 °C (lit.)
Appearancewhite crystal
EINECS208-219-5
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 516-05-2 |
| Catalog No. | 2A-9022436 |
| Chinese Name | 甲基丙二酸 |
| Synonyms | Methylmalonic acid; Methylpropanedioic acid; EINECS 208-219-5; 2-Methylmalonic acid; methyl-Propanedioic acid; 2-Methylpropanedioic acid; MFCD00002656; methyl-Malonic acid; 2-Methyl1-malonic acid; Methylmalonate |
| Molecular Formula | CH3CH(CO2H)2 |
| Molecular Weight | 118.09 |
| Purity | 99 |
| Density | 1.45 |
| Boiling Point | 334.4±25.0 °C at 760 mmHg |
| Melting Point | 128-130 °C (lit.) |
| Appearance | white crystal |
| Water Solubility | soluble |
| Storage Condition | Store in a cool, dry, well-ventilated warehouse. K |
| Application | Methylmalonate is an indicator of vitamin B-12 deficiency in cancer patients. |
| EINECS | 208-219-5 |
| HTC | 2917190090 |
| PubChem ID | 24896996 |
| MDL Number | MFCD00002656 |
| SMILES | CC(C(O)=O)C(O)=O |
| InChI | 1S/C4H6O4/c1-2(3(5)6)4(7)8/h2H,1H3,(H,5,6)(H,7,8) |
| InChI Key | ZIYVHBGGAOATLY-UHFFFAOYSA-N |
| Beilstein/REAXYS | 1756084 |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Hazard Symbols | Transport |
| MSDS | msds/22436_1_516_05_2.pdf |
| Bioactivity | Methylmalonate is an indicator of Vitamin B-12 deficiency in cancer. Related Catalog Natural Products >> Acids and Aldehydes Research Areas >> Cancer Target Human Endogenous Metabolite In Vitro Vitamin B-12 is required for Methylmalonate (Methylmalonic acid; MMA) to be converted to succinyl-CoA, and in combination with folic acid, for homocysteine (HC) to be converted to methionine. Therefore, Methylmalonate is clearly more specific to vitamin B-12 deficiency compared to HC[1]. References [1]. Vashi P, et al. Methylmalonic Acid and Homocysteine as Indicators of Vitamin B-12 Deficiency in Cancer. PLoS One. 2016 Jan 25;11(1):e0147843. Chemical & Physical Properties Density 1.45 Boiling Point 334.4±25.0 °C at 760 mmHg Melting Point 129-136 ºC Molecular Formula C4H6O4 Molecular Weight 118.088 Flash Point 170.2±19.7 °C Exact Mass 118.026611 PSA 74.60000 LogP -0.21 Vapour Pressure 0.0±1.5 mmHg at 25°C Index of Refraction 1.474 InChIKey ZIYVHBGGAOATLY-UHFFFAOYSA-N SMILES CC(C(=O)O)C(=O)O Storage condition ?20°C Water Solubility soluble |
| Use of | Methylmalonate is an indicator of Vitamin B-12 deficiency in cancer. Properties Articles90 Name ethylmalonic acid Synonym More Synonyms Methylmalonic acid Biological Activity Description Methylmalonate is an indicator of Vitamin B-12 deficiency in cancer. Related Catalog Natural Products >> Acids and Aldehydes Research Areas >> Cancer Human Endogenous Metabolite In Vitro Vitamin B-12 is required for Methylmalonate (Methylmalonic acid; MMA) to be converted to succinyl-CoA, and in combination with folic acid, for homocysteine (HC) to be converted to methionine. Therefore, Methylmalonate is clearly more specific to vitamin B-12 deficiency compared to HC[1]. References [1]. Vashi P, et al. Methylmalonic Acid and Homocysteine as Indicators of Vitamin B-12 Deficiency in Cancer. PLoS One. 2016 Jan 25;11(1):e0147843. Chemical & Physical Properties Molecular Formula C4H6O4 Exact Mass 118.026611 PSA 74.60000 LogP -0.21 Index of Refraction 1.474 InChIKey ZIYVHBGGAOATLY-UHFFFAOYSA-N SMILES CC(C(=O)O)C(=O)O Water Solubility soluble |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: No dangerous goods IMDG Code: No dangerous goods International Air Transport Dangerous Regulations: No dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special precautions for users No data available |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| 1-Chloro-2-methyl-2-phenylpropane | 515-40-2 | 2A-9022425 |
| Sodium benzenesulfonate | 515-42-4 | 2A-9022426 |
| Ethyl benzenesulphonate | 515-46-8 | 2A-9022427 |
| Ammonium lactate | 515-98-0 | 2A-9022433 |
| Barium oxalate | 516-02-9 | 2A-9022434 |
| Taurochenodeoxycholic acid | 516-35-8 | 2A-9022439 |
| 2-Acetylbutyrolactone | 517-23-7 | 2A-9022442 |
| Hematoxylin | 517-28-2 | 2A-0202046 |
| Rubrene | 517-51-1 | 2A-9022445 |
| Alkannin | 517-88-4 | 2A-9022446 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS