CAS Number463-40-1
SynonymsEINECS 207-334-8; (9Z,12Z,15Z)-linolenic acid; 9,12,15-all-cis-Octadecatrienoic acid; Linolein,2-mono; 2-linoleoyl-sn-glycerol; 2-Monolinolein; (9Z,12Z,15Z)-Octadeca-9,12,15-trienoic acid; 2-Glyceryl 9,12-octadecadienoate; 9,12-Octadecadienoic acid (Z,Z)-,2-hydroxy-1-(hydroxymethyl)ethyl ester; linoleic acid monoacylglycerol; Glyceryl 2-linoleate; 9Z,12Z,15Z-octadecatrienic acid; 2-monolinoleoylglycerol; 9Z,12Z,15Z-Octadecatrienoic acid; (9Z,12Z,15Z)-9,12,15-Octadecatrienoic acid; MFCD00065720; a-Linolenic Acid; octadecatrienoic acid; 9,12,15-octadecatrienoic acid; alpha-linolenic acid; (all-Z)-9,12,15-Octadecatrienoic acid; (9Z,12Z)-1,3-dihydroxypropan-2-yl octadeca-9,12-dienoate; Linolenic acid; C18:3 (9,12,15-cis all); 2-Linoleoylglycerol
Molecular FormulaCH3(CH2CH=CH)3(CH2)7CO2H
Molecular Weight278.43
Purity≥99%
Density0.9±0.1 g/cm3
Boiling Point230-232 °C/1 mmHg (lit.)
Melting Point-11 °C (lit.)
AppearanceTransparent to light yellow liquid
EINECS207-334-8
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 463-40-1 |
| Catalog No. | 2A-9022058 |
| Chinese Name | α-亚麻酸 |
| Synonyms | EINECS 207-334-8; (9Z,12Z,15Z)-linolenic acid; 9,12,15-all-cis-Octadecatrienoic acid; Linolein,2-mono; 2-linoleoyl-sn-glycerol; 2-Monolinolein; (9Z,12Z,15Z)-Octadeca-9,12,15-trienoic acid; 2-Glyceryl 9,12-octadecadienoate; 9,12-Octadecadienoic acid (Z,Z)-,2-hydroxy-1-(hydroxymethyl)ethyl ester; linoleic acid monoacylglycerol; Glyceryl 2-linoleate; 9Z,12Z,15Z-octadecatrienic acid; 2-monolinoleoylglycerol; 9Z,12Z,15Z-Octadecatrienoic acid; (9Z,12Z,15Z)-9,12,15-Octadecatrienoic acid; MFCD00065720; a-Linolenic Acid; octadecatrienoic acid; 9,12,15-octadecatrienoic acid; alpha-linolenic acid; (all-Z)-9,12,15-Octadecatrienoic acid; (9Z,12Z)-1,3-dihydroxypropan-2-yl octadeca-9,12-dienoate; Linolenic acid; C18:3 (9,12,15-cis all); 2-Linoleoylglycerol |
| Molecular Formula | CH3(CH2CH=CH)3(CH2)7CO2H |
| Molecular Weight | 278.43 |
| Purity | ≥99 |
| Density | 0.9±0.1 g/cm3 |
| Boiling Point | 230-232 °C/1 mmHg (lit.) |
| Melting Point | -11 °C (lit.) |
| Appearance | Transparent to light yellow liquid |
| Water Solubility | INSOLUBLE |
| Storage Condition | Sealed and light-proof, nitrogen-filled packaging. |
| Application | α-Linolenic acid is isolated from seed oil and is an essential fatty acid that cannot be synthesized by the human body. α-Linolenic acid affects the thrombotic process by modulating PI3K/Akt signaling |
| EINECS | 207-334-8 |
| HTC | 2916190090 |
| PubChem ID | 24896311 |
| MDL Number | MFCD00065720 |
| SMILES | CC/C=C\C/C=C\C/C=C\CCCCCCCC(O)=O |
| InChI | 1S/C18H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h3-4,6-7,9-10H,2,5,8,11-17H2,1H3,(H,19,20)/b4-3-,7-6-,10-9- |
| InChI Key | DTOSIQBPPRVQHS-PDBXOOCHSA-N |
| Beilstein/REAXYS | 1727693 |
| NACRES Code | NA.77 |
| UNSPSC | 12352106 |
| Hazard Symbols | Transport |
| MSDS | msds/22058_1_463_40_1.pdf |
| Bioactivity | α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1]. Related Catalog Research Areas >> Cancer Research Areas >> Cardiovascular Disease Signaling Pathways >> PI3K/Akt/mTOR >> PI3K Signaling Pathways >> PI3K/Akt/mTOR >> Akt Target PI3K Akt In Vitro α-Linolenic acid converses into the longer chain fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)[1]. In Vivo α-Linolenic acid (50, 100, 250 mg/kg; for 10 days) can completely inhibit collagen- and adrenaline-induced thrombosis in mice at 250 mg/kg[1]. α-Linolenic acid (35, 70, 175 mg/kg) suppresses A-V thrombus formation in rats (weighing at 250 ~ 300 g)[1]. α-Linolenic acid (70 or 175 mg/kg) inhibits collagen stimulated platelet aggregation in rats[1]. Animal Model: Mice weighing at 18 ~ 22 g[1] Dosage: 50, 100, 250 mg/kg Administration: For 10 days Result: Completely inhibited collagen- and adrenaline-induced thrombosis at 250 mg/kg. References [1]. Yang Q, et al. Anti-thrombotic effects of α-linolenic acid isolated from Zanthoxylum bungeanum Maxim seeds. BMC Complement Altern Med. 2014 Sep 23;14:348. Chemical & Physical Properties Density 0.9±0.1 g/cm3 Boiling Point 443.4±0.0 °C at 760 mmHg Melting Point -11 °C(lit.) Molecular Formula C18H30O2 Molecular Weight 278.430 Flash Point 275.7±14.4 °C Exact Mass 278.224579 PSA 37.30000 LogP 6.50 Vapour Pressure 0.0±2.3 mmHg at 25°C Index of Refraction 1.491 Storage condition 2-8°C Water Solubility INSOLUBLE |
| Use of | α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1]. Properties Articles113 Name α-linolenic acid Synonym More Synonyms Linolenic acid Biological Activity Description α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1]. Related Catalog Research Areas >> Cancer Research Areas >> Cardiovascular Disease Signaling Pathways >> PI3K/Akt/mTOR >> PI3K Signaling Pathways >> PI3K/Akt/mTOR >> Akt In Vitro α-Linolenic acid converses into the longer chain fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)[1]. References [1]. Yang Q, et al. Anti-thrombotic effects of α-linolenic acid isolated from Zanthoxylum bungeanum Maxim seeds. BMC Complement Altern Med. 2014 Sep 23;14:348. Chemical & Physical Properties Molecular Formula C18H30O2 Exact Mass 278.224579 PSA 37.30000 Index of Refraction 1.491 Water Solubility INSOLUBLE |
| Tax Rebate | 9.0% |
| Supervision | A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Inspection | R. Imported food hygiene supervision and inspection S. Export food hygiene supervision and inspection M. Imported commodity inspection N. Exported commodity inspection |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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