CAS Number454-29-5
SynonymsDL-HoMocysteine; DL-2-amino-4-mercapto-Butyric acid; D-L-homocysteine; usafb-12; DL-2-Amino-4-mercaptobutyric acid; 2-Amino-4-mercaptobutyric acid; D,L-Homocysteine; 2-Amino-4-mercaptobutanoic acid; HOMOCYSTEINE,DL; 2-AMINO-4-MERCAPTOBUYRIC ACID; 2-amino-4-mercapto-DL-Butyric acid; 2-amino-4-sulfanylbutanoic acid; Homocysteine (VAN); TOTALHOMOCYSTEINE; H-DL-Hcys-OH; 2-Amino-4-Mercapto-Butyric Acid; EINECS 207-222-9; homocystine; (±)-Homocysteine; 2-amino-4-mercapto-Butanoic acid; UNII:S7IJP4A89K; MFCD00004898; Homocysteine; 2-thioethylglycine
Molecular FormulaHSCH2CH2CH(NH2)COOH
Molecular Weight135.18
Purity≥95 (titration)%
Density1.3±0.1 g/cm3
Boiling Point299.7±35.0 °C at 760 mmHg
Melting Point232-233 °C (lit.)
Appearancepowder
EINECS207-222-9
Symbol
Signal WordWarning
Please Login or Create an Account to: See VlP prices and availability
US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 454-29-5 |
| Catalog No. | 2A-9021964 |
| Chinese Name | DL-高半胱氨酸 |
| Synonyms | DL-HoMocysteine; DL-2-amino-4-mercapto-Butyric acid; D-L-homocysteine; usafb-12; DL-2-Amino-4-mercaptobutyric acid; 2-Amino-4-mercaptobutyric acid; D,L-Homocysteine; 2-Amino-4-mercaptobutanoic acid; HOMOCYSTEINE,DL; 2-AMINO-4-MERCAPTOBUYRIC ACID; 2-amino-4-mercapto-DL-Butyric acid; 2-amino-4-sulfanylbutanoic acid; Homocysteine (VAN); TOTALHOMOCYSTEINE; H-DL-Hcys-OH; 2-Amino-4-Mercapto-Butyric Acid; EINECS 207-222-9; homocystine; (±)-Homocysteine; 2-amino-4-mercapto-Butanoic acid; UNII:S7IJP4A89K; MFCD00004898; Homocysteine; 2-thioethylglycine |
| Molecular Formula | HSCH2CH2CH(NH2)COOH |
| Molecular Weight | 135.18 |
| Purity | ≥95 (titration) |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 299.7±35.0 °C at 760 mmHg |
| Melting Point | 232-233 °C (lit.) |
| Appearance | powder |
| Storage Condition | Store sealed at 2-8°C, placed in a ventilated, dry |
| Application | DL-Homocysteine is a weak neurotoxin that affects kynurenic acid production. |
| EINECS | 207-222-9 |
| HTC | 2930909090 |
| PubChem ID | 24895646 |
| MDL Number | MFCD00004898 |
| SMILES | NC(CCS)C(O)=O |
| InChI | 1S/C4H9NO2S/c5-3(1-2-8)4(6)7/h3,8H,1-2,5H2,(H,6,7) |
| InChI Key | FFFHZYDWPBMWHY-UHFFFAOYSA-N |
| Beilstein/REAXYS | 1721683 |
| NACRES Code | NA.26 |
| eCl@ss | 42021308 |
| UNSPSC | 12352209 |
| Hazard Symbols | Transport |
| MSDS | msds/21964_1_454_29_5.pdf |
| Bioactivity | DL-Homocysteine is a weak neurotoxin, and can affect the production of kynurenic acid in the brain. Related Catalog Natural Products >> Others Research Areas >> Others Target Human Endogenous Metabolite In Vitro DL-Homocysteine (0.1-0.5 mM) significantly enhances kynurenic acid (KYNA) production in rat cortical slices, and diministes the production of at 3.0, 5.0, and 10.0 mM, with the estimated IC50 of 6.4 (5.5-7.5) mM. DL-Homocysteine dose-dependently inhibits kynurenine aminotransferases I (KATI) activity at concentrations ≥0.2 mM, with an IC50 of 0.566 (0.442-0.724) mM, and the activity of KAT II with IC50 value of 8.046 (5.804-11.154) mM[1]. In Vivo DL-Homocysteine (1.3 mmol/kg, i.p.) increases KYNA content (pmol/g tissue) from 8.47 ± 1.57 to 13.04 ± 2.86 and 11.4 ± 1.72 in cortex, and from 4.11 ± 1.54 to 10.02 ± 3.08 in rat hippocampus[1]. References [1]. DL-Homocysteine, et al. Dual effect of DL-homocysteine and S-adenosylhomocysteine on brain synthesis of the glutamate receptor antagonist, kynurenic acid. J Neurosci Res. 2005 Feb 1;79(3):375-82. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 299.7±35.0 °C at 760 mmHg Melting Point 232-233 °C(lit.) Molecular Formula C4H9NO2S Molecular Weight 135.185 Flash Point 135.0±25.9 °C Exact Mass 135.035400 PSA 102.12000 LogP 0.22 Vapour Pressure 0.0±1.3 mmHg at 25°C Index of Refraction 1.538 InChIKey FFFHZYDWPBMWHY-UHFFFAOYSA-N SMILES NC(CCS)C(=O)O Storage condition 2-8°C Stability Stable. Combustible. Incompatible with strong oxidizing agents. |
| Use of | DL-Homocysteine is a weak neurotoxin, and can affect the production of kynurenic acid in the brain. Properties Articles182 Name DL-Homocysteine Synonym More Synonyms DL-Homocysteine Biological Activity Description DL-Homocysteine is a weak neurotoxin, and can affect the production of kynurenic acid in the brain. Related Catalog Natural Products >> Others Research Areas >> Others Human Endogenous Metabolite References [1]. DL-Homocysteine, et al. Dual effect of DL-homocysteine and S-adenosylhomocysteine on brain synthesis of the glutamate receptor antagonist, kynurenic acid. J Neurosci Res. 2005 Feb 1;79(3):375-82. Chemical & Physical Properties Molecular Formula C4H9NO2S Exact Mass 135.035400 PSA 102.12000 Index of Refraction 1.538 InChIKey FFFHZYDWPBMWHY-UHFFFAOYSA-N SMILES NC(CCS)C(=O)O Stability Stable. Combustible. Incompatible with strong oxidizing agents. |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 95.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| 3-Fluoro-4-methoxyphenol | 452-11-9 | 2A-9021931 |
| 3-Fluoro-4-methoxyphenylacetic acid | 452-14-2 | 2A-9021932 |
| 4-Methylcatechol | 452-86-8 | 2A-9021956 |
| Cuscohygrine | 454-14-8 | 2A-9021962 |
| 2-Fluoro-5-nitroanisole | 454-16-0 | 2A-9021963 |
| Ethyl difluoroacetate | 454-31-9 | 2A-9021965 |
| 3-Fluoro-5-nitrobenzotrifluoride | 454-73-9 | 2A-9021967 |
| 4-Fluorophenyl methyl sulphone | 455-15-2 | 2A-9021976 |
| Ethyl 3-amino-4-fluorobenzoate | 455-75-4 | 2A-9021984 |
| 4-Amino-3-fluorobenzoic acid | 455-87-8 | 2A-9021986 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS