CAS Number452-06-2
Synonyms2-Aminoperin; iso-Adenine; 2-Aminopurine; 3H-Purin-2-amine; MFCD07357244; 7H-Purin-2-amine; 9H-Purin-2-amine; 2-amino purine; EINECS 207-197-4; 9H-purin-2-ylamine; 2-amino-6-purine; 1H-Purin-2-amine; 4-aminopurine; 2-amino-purin; SQ 22,451
Molecular FormulaC5H5N5
Molecular Weight135.13
Purity≥99%
Density1.9±0.1 g/cm3
Boiling Point328.2±25.0 °C at 760 mmHg
Melting Point280-282 °C (lit.)
Appearancepowder
EINECS207-197-4
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 452-06-2 |
| Catalog No. | 2A-9021927 |
| Chinese Name | 2-氨基嘌呤 |
| Synonyms | 2-Aminoperin; iso-Adenine; 2-Aminopurine; 3H-Purin-2-amine; MFCD07357244; 7H-Purin-2-amine; 9H-Purin-2-amine; 2-amino purine; EINECS 207-197-4; 9H-purin-2-ylamine; 2-amino-6-purine; 1H-Purin-2-amine; 4-aminopurine; 2-amino-purin; SQ 22,451 |
| Molecular Formula | C5H5N5 |
| Molecular Weight | 135.13 |
| Purity | ≥99 |
| Density | 1.9±0.1 g/cm3 |
| Boiling Point | 328.2±25.0 °C at 760 mmHg |
| Melting Point | 280-282 °C (lit.) |
| Appearance | powder |
| Storage Condition | 1. This product should be kept sealed. |
| Application | 2-Aminopurine is a fluorescent analog of guanine and adenosine, and is a widely used DNA structure probe based on fluorescence attenuation. When 2-aminopurine is inserted into anoligonucleotide, its f |
| EINECS | 207-197-4 |
| HTC | 2933990090 |
| PubChem ID | 24890778 |
| MDL Number | MFCD00005566 |
| SMILES | Nc1ncc2[nH]cnc2n1 |
| InChI | 1S/C5H5N5/c6-5-7-1-3-4(10-5)9-2-8-3/h1-2H,(H3,6,7,8,9,10) |
| InChI Key | MWBWWFOAEOYUST-UHFFFAOYSA-N |
| NACRES Code | NA.51 |
| UNSPSC | 41106305 |
| Hazard Symbols | Transport |
| MSDS | msds/21927_1_452_06_2.pdf |
| Bioactivity | 2-Aminopurine, a fluorescent analog of guanosine and adenosine, is a widely used fluorescence-decay-based probe of DNA structure. When 2-Aminopurine is inserted in anoligonucleotide, its fluorescence is highly quenched by stacking with the natural bases. 2-Aminopurine has been used to probe nucleic acid structure and dynamics[1][2]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others In Vitro 2-Aminopurine (2AP) is not valuable as afluorescent label because its fluorescence is highly quenched by stacking with the natural bases, when it is inserted in anoligonucleotide. However, it is this very susceptibility to interbase quenching that makes 2AP an exquisitely sensitivefluorescent probe of nucleic acid structure[1]. 2-Aminopurine differs from adenine (6-aminopurine) only in the position of the exocyclic amine group, and yet its fluorescence intensity is one thousand times that of adenine[1]. References [1]. J M Jean, et al. 2-Aminopurine fluorescence quenching and lifetimes: role of base stacking. Proc Natl Acad Sci U S A. 2001 Jan 2;98(1):37-41. [2]. Dehong Tan, et al. Decreased glycation and structural protection properties of γ-glutamyl-S-allyl-cysteine peptide isolated from fresh garlic scales (Allium sativum L.). Nat Prod Res. 2015;29(23):2219-22. Chemical & Physical Properties Density 1.9±0.1 g/cm3 Boiling Point 328.2±25.0 °C at 760 mmHg Melting Point 280-282 °C(lit.) Molecular Formula C5H5N5 Molecular Weight 135.127 Flash Point 152.3±23.2 °C Exact Mass 135.054489 PSA 80.48000 LogP -1.33 Vapour Pressure 0.0±0.7 mmHg at 25°C Index of Refraction 1.954 InChIKey MWBWWFOAEOYUST-UHFFFAOYSA-N SMILES Nc1ncc2[nH]cnc2n1 |
| Use of | Properties Articles54 Name 2-aminopurine Synonym More Synonyms 2-Aminopurine Biological Activity Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. J M Jean, et al. 2-Aminopurine fluorescence quenching and lifetimes: role of base stacking. Proc Natl Acad Sci U S A. 2001 Jan 2;98(1):37-41. [2]. Dehong Tan, et al. Decreased glycation and structural protection properties of γ-glutamyl-S-allyl-cysteine peptide isolated from fresh garlic scales (Allium sativum L.). Nat Prod Res. 2015;29(23):2219-22. Chemical & Physical Properties Molecular Formula C5H5N5 Exact Mass 135.054489 PSA 80.48000 LogP -1.33 Index of Refraction 1.954 InChIKey MWBWWFOAEOYUST-UHFFFAOYSA-N SMILES Nc1ncc2[nH]cnc2n1 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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