CAS Number356-12-7
SynonymsEthylacetat; 16a,17a-Isopropylidene-6a-fluorotriamcinolone 21-Acetate; FLUOCINONIDE; 21-Acetoxy-6a,9a-difluoro-11b-hydroxy-16a,17a-isopropylidenedioxy-1,4-pregnadiene-3,20-dione; oethyl acetate
Molecular FormulaC26H32F2O7
Molecular Weight494.53
Purity98.00%
Density1.3±0.1 g/cm3
Boiling Point591.1±50.0 °C at 760 mmHg
Melting Point309ºC
AppearanceWhite crystalline powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 356-12-7 |
| Catalog No. | 2A-9021480 |
| Chinese Name | 醋酸氟轻松 |
| Synonyms | Ethylacetat; 16a,17a-Isopropylidene-6a-fluorotriamcinolone 21-Acetate; FLUOCINONIDE; 21-Acetoxy-6a,9a-difluoro-11b-hydroxy-16a,17a-isopropylidenedioxy-1,4-pregnadiene-3,20-dione; oethyl acetate |
| Molecular Formula | C26H32F2O7 |
| Molecular Weight | 494.53 |
| Purity | 98.00 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 591.1±50.0 °C at 760 mmHg |
| Melting Point | 309ºC |
| Appearance | White crystalline powder |
| Storage Condition | Room Temperature |
| Packaging | I |
| Application | Fluocinonide (Vanos) is a glucocorticoid steroid with anti-inflammatory activity that acts on skin diseases. |
| HTC | 2937210000 |
| MDL Number | C26H32F2O7 |
| SMILES | CC(=O)OCC(=O)C12OC(C)(C)OC1CC1C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC12C |
| InChI | InChI=1S/C26H32F2O7/c1-13(29)33-12-20(32)26-21(34-22(2,3)35-26)10-15-16-9-18(27)17-8-14(30)6-7-23(17,4)25(16,28)19(31)11-24(15,26)5/h6-8,15-16,18-19,21,31H,9-12H2,1-5H3/t15-,16-,18-,19-,21+,23-,24-,25-,26+/m0/s1 |
| InChI Key | WJOHZNCJWYWUJD-IUGZLZTKSA-N |
| Hazard Symbols | 6.1(a) |
| MSDS | msds/21480_1_356_12_7.pdf |
| Bioactivity | Fluocinonide (Vanos) is a potent glucocorticoid steroid used topically as anti-inflammatory agent for the treatment of skin disorders.Target: Glucocorticoid ReceptorFluocinonide is a potent glucocorticoid steroid used topically as an anti-inflammatory agent for the treatment of skin disorders such as eczema and seborrhoeic dermatitis. Fluocinonide ranks as a "high-potency" topical corticosteroid. Minimal amounts should be used for a minimal length of time to avoid the occurrence of adverse effects. Fluocinonide should not be used if infection is present. Fluocinonide is used in veterinary medicine. It is a treatment for allergies in dogs. Natural systemic cortisol concentrations can be suppressed for weeks after one week of topical exposure. From Wikipedia. Related Catalog Signaling Pathways >> GPCR/G Protein >> Glucocorticoid Receptor Research Areas >> Inflammation/Immunology References [1]. http://en.wikipedia.org/wiki/Fluocinonide Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 591.1±50.0 °C at 760 mmHg Melting Point 309ºC Molecular Formula C26H32F2O7 Molecular Weight 494.525 Flash Point 311.3±30.1 °C Exact Mass 494.211609 PSA 99.13000 LogP 3.36 Vapour Pressure 0.0±3.8 mmHg at 25°C Index of Refraction 1.560 InChIKey WJOHZNCJWYWUJD-IUGZLZTKSA-N SMILES CC(=O)OCC(=O)C12OC(C)(C)OC1CC1C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC12C |
| Use of | Fluocinonide (Vanos) is a potent glucocorticoid steroid used topically as anti-inflammatory agent for the treatment of skin disorders.Target: Glucocorticoid ReceptorFluocinonide is a potent glucocorticoid steroid used topically as an anti-inflammatory agent for the treatment of skin disorders such as eczema and seborrhoeic dermatitis. Fluocinonide ranks as a "high-potency" topical corticosteroid. Minimal amounts should be used for a minimal length of time to avoid the occurrence of adverse effects. Fluocinonide should not be used if infection is present. Fluocinonide is used in veterinary medicine. It is a treatment for allergies in dogs. Natural systemic cortisol concentrations can be suppressed for weeks after one week of topical exposure. From Wikipedia. Properties Articles27 Name Fluocinolone Acetonide Acetate Synonym More Synonyms FLUOCINONIDE Biological Activity Description Fluocinonide (Vanos) is a potent glucocorticoid steroid used topically as anti-inflammatory agent for the treatment of skin disorders.Target: Glucocorticoid ReceptorFluocinonide is a potent glucocorticoid steroid used topically as an anti-inflammatory agent for the treatment of skin disorders such as eczema and seborrhoeic dermatitis. Fluocinonide ranks as a "high-potency" topical corticosteroid. Minimal amounts should be used for a minimal length of time to avoid the occurrence of adverse effects. Fluocinonide should not be used if infection is present. Fluocinonide is used in veterinary medicine. It is a treatment for allergies in dogs. Natural systemic cortisol concentrations can be suppressed for weeks after one week of topical exposure. From Wikipedia. Related Catalog Signaling Pathways >> GPCR/G Protein >> Glucocorticoid Receptor Research Areas >> Inflammation/Immunology References [1]. http://en.wikipedia.org/wiki/Fluocinonide Chemical & Physical Properties Molecular Formula C26H32F2O7 Exact Mass 494.211609 PSA 99.13000 Index of Refraction 1.560 InChIKey WJOHZNCJWYWUJD-IUGZLZTKSA-N |
| Transport Info | Product name: Fluorocycline |
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