CAS Number149-87-1
SynonymsMFCD00064322; L-Pidolic acid; H-DL-Pyr-OH; DL-2-Pyrrolidone-5-carboxylic acid; (S)-(-)-2-pyrrolidone-5-carboxylic acid; Ajidew A 100; Pyrrolidonecarboxylic acid; (S)-(-)-γ-Butyrolactam-γ-carboxylic acid; PyroGlu; 5-Oxopyrrolidine-2-carboxylic Acid; Pyroglutamic acid; L-5-Oxoproline; DL-Pyroglutamic acid; (S)-(−)-Pyroglutamic acid; a-Aminoglutaric Acid Lactam; 5-oxo-proline; (S)-(−)-2-Pyrrolidone-5-carboxylic acid; (-)-Pyroglutamic acid; L-Glutamic Acid g-Lactam; 5-Oxo-L-proline; 5-Pyrrolidinone-2-carboxylic acid; D,l-2-Pyrrolidone-5-Carboxylic Acid; PCA; Glutamic Acid Lactam; 2-L-Pyrrolidone-5-carboxylic acid; pidolic acid; EINECS 205-748-3; (2S)-5-Hydroxy-3,4-dihydro-2H-pyrrole-2-carboxylic acid; DL-Glutamic Acid Lactam; 5-L-oxoproline
Molecular FormulaC5H7NO3
Molecular Weight129.11
Purity99%
Density1.4±0.1 g/cm3
Boiling Point453.1±38.0 °C at 760 mmHg
Melting Point183-185 °C (lit.)
Appearancewhite powder
EINECS205-748-3
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 149-87-1 |
| Catalog No. | 2A-9020999 |
| Chinese Name | DL-焦谷氨酸 |
| Synonyms | MFCD00064322; L-Pidolic acid; H-DL-Pyr-OH; DL-2-Pyrrolidone-5-carboxylic acid; (S)-(-)-2-pyrrolidone-5-carboxylic acid; Ajidew A 100; Pyrrolidonecarboxylic acid; (S)-(-)-γ-Butyrolactam-γ-carboxylic acid; PyroGlu; 5-Oxopyrrolidine-2-carboxylic Acid; Pyroglutamic acid; L-5-Oxoproline; DL-Pyroglutamic acid; (S)-(−)-Pyroglutamic acid; a-Aminoglutaric Acid Lactam; 5-oxo-proline; (S)-(−)-2-Pyrrolidone-5-carboxylic acid; (-)-Pyroglutamic acid; L-Glutamic Acid g-Lactam; 5-Oxo-L-proline; 5-Pyrrolidinone-2-carboxylic acid; D,l-2-Pyrrolidone-5-Carboxylic Acid; PCA; Glutamic Acid Lactam; 2-L-Pyrrolidone-5-carboxylic acid; pidolic acid; EINECS 205-748-3; (2S)-5-Hydroxy-3,4-dihydro-2H-pyrrole-2-carboxylic acid; DL-Glutamic Acid Lactam; 5-L-oxoproline |
| Molecular Formula | C5H7NO3 |
| Molecular Weight | 129.11 |
| Purity | 99 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 453.1±38.0 °C at 760 mmHg |
| Melting Point | 183-185 °C (lit.) |
| Appearance | white powder |
| Water Solubility | 5.67 g/100 mL (20 ºC) |
| Storage Condition | Store in a dry and cool place. |
| Application | DL-Pyroglutamic acid (CAE) acts as a surface inactivator for hepatitis B and inactivates vaccinia virus, herpes simplex virus and influenza virus except poliovirus. DL-pyroglutamic acid is also a poss |
| EINECS | 205-748-3 |
| HTC | 29337900 |
| PubChem ID | 24857617 |
| MDL Number | MFCD00064322 |
| SMILES | OC(=O)C1CCC(=O)N1 |
| InChI | 1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9) |
| InChI Key | ODHCTXKNWHHXJC-UHFFFAOYSA-N |
| Beilstein/REAXYS | 82134 |
| NACRES Code | NA.22 |
| UNSPSC | 12352106 |
| Hazard Symbols | Transport |
| MSDS | msds/20999_1_149_87_1.pdf |
| Bioactivity | DL-Pyroglutamic acid (CAE) as an inactivator of hepatitis B surface, inactivates vaccinia virus, herpes simplex virus, and influenza virus except poliovirus. DL-Pyroglutamic acid is also a possible inhibitor of GABA transaminase, increases GABA amount with antiepileptic action[1][2]. Related Catalog Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Signaling Pathways >> Neuronal Signaling >> GABA Receptor In Vitro DL-Pyroglutamic acid results 50 and 100% inactivation of the antigen of 0.01-0.025% and 0.025-0.05%, respectively[1]. DL-Pyroglutamic acid is a possible glutamate antagonist, blocks glutamate miniature-end-plate potential in locust muscle-Druce and Bradford[2]. In Vivo DL-Pyroglutamic acid (0.775 mM/L) completely abolishes the myoclonic jerks and EEG spikes in rats model of epileptic by cobalt implantation in the sensorimotor cerebral cortex[2]. References [1]. Sugimoto Y, et al. N-alpha-Cocoyl-L-arginine ethyl ester, DL-pyroglutamic acid salt, as an inactivator of hepatitis B surface antigen. Antimicrob Agents Chemother. 1979 Sep;16(3):329-32. Chemical & Physical Properties Density 1.4±0.1 g/cm3 Boiling Point 453.1±38.0 °C at 760 mmHg Melting Point 180-185ºC Molecular Formula C5H7NO3 Molecular Weight 129.114 Flash Point 227.8±26.8 °C Exact Mass 129.042587 PSA 66.40000 LogP -2.39 Vapour Pressure 0.0±2.4 mmHg at 25°C Index of Refraction 1.512 InChIKey ODHCTXKNWHHXJC-UHFFFAOYSA-N SMILES O=C1CCC(C(=O)O)N1 Water Solubility 5.67 g/100 mL (20 ºC) |
| Use of | DL-Pyroglutamic acid (CAE) as an inactivator of hepatitis B surface, inactivates vaccinia virus, herpes simplex virus, and influenza virus except poliovirus. DL-Pyroglutamic acid is also a possible inhibitor of GABA transaminase, increases GABA amount with antiepileptic action[1][2]. Properties Name 5-oxoproline Synonym More Synonyms 5-Oxopyrrolidine-2-carboxylic acid Biological Activity Description DL-Pyroglutamic acid (CAE) as an inactivator of hepatitis B surface, inactivates vaccinia virus, herpes simplex virus, and influenza virus except poliovirus. DL-Pyroglutamic acid is also a possible inhibitor of GABA transaminase, increases GABA amount with antiepileptic action[1][2]. Related Catalog Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Signaling Pathways >> Neuronal Signaling >> GABA Receptor In Vitro DL-Pyroglutamic acid results 50 and 100% inactivation of the antigen of 0.01-0.025% and 0.025-0.05%, respectively[1]. DL-Pyroglutamic acid is a possible glutamate antagonist, blocks glutamate miniature-end-plate potential in locust muscle-Druce and Bradford[2]. References [1]. Sugimoto Y, et al. N-alpha-Cocoyl-L-arginine ethyl ester, DL-pyroglutamic acid salt, as an inactivator of hepatitis B surface antigen. Antimicrob Agents Chemother. 1979 Sep;16(3):329-32. Chemical & Physical Properties Molecular Formula C5H7NO3 Exact Mass 129.042587 PSA 66.40000 LogP -2.39 Index of Refraction 1.512 InChIKey ODHCTXKNWHHXJC-UHFFFAOYSA-N |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 9.0% Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| 1,8-Dihydroxynaphthylene-3,6-disulfonic acid | 148-25-4 | 2A-9020982 |
| 3-Hydroxynaphthalene-2,7-disulphonic acid | 148-75-4 | 2A-9020987 |
| Thiabendazole | 148-79-8 | 2A-9020988 |
| Tiron | 149-45-1 | 2A-9020995 |
| rac Geosmin-d3 | 135441-88-2 | 2A-9020996 |
| 3-Methoxyphenol | 150-19-6 | 2A-9021002 |
| BICINE Buffer | 150-25-4 | 2A-9021003 |
| N-(2-Hydroxyethyl)ethylenediaminetriacetic acid | 150-39-0 | 2A-9021005 |
| Triethyl borate | 150-46-9 | 2A-9021006 |
| Alverine | 150-59-4 | 2A-9021007 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS