CAS Number148-53-8
Synonyms2-Hydroxy-3-(methyloxy)benzaldehyde; ORTHO-VANILLIN; VHR BQ CO1; 2-Hydroxy-m-anisaldehyde; EINECS 205-715-3; o-Vanillin; 3-Methoxysalicylaldehyde; MFCD00003322; 2-Hydroxy-3-methoxybenzaldehyde
Molecular FormulaCH3OC6H3-2-(OH)CHO
Molecular Weight152.15
Purity99%
Density1.2±0.1 g/cm3
Boiling Point265-266 °C (lit.)
Melting Point40-42 °C (lit.)
Appearancesolid
EINECS205-715-3
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 148-53-8 |
| Catalog No. | 2A-9020984 |
| Chinese Name | 邻香草醛 |
| Synonyms | 2-Hydroxy-3-(methyloxy)benzaldehyde; ORTHO-VANILLIN; VHR BQ CO1; 2-Hydroxy-m-anisaldehyde; EINECS 205-715-3; o-Vanillin; 3-Methoxysalicylaldehyde; MFCD00003322; 2-Hydroxy-3-methoxybenzaldehyde |
| Molecular Formula | CH3OC6H3-2-(OH)CHO |
| Molecular Weight | 152.15 |
| Purity | 99 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 265-266 °C (lit.) |
| Melting Point | 40-42 °C (lit.) |
| Appearance | solid |
| Water Solubility | slightly soluble |
| Storage Condition | Store in a dry and cool place. |
| Application | 2-Vanillin is a natural product that can be extracted from vanillin and red pine fruits. O-vanillin is a potent antifungal agent. O-vanillin inhibits the growth of mycelium by destroying the integrity |
| EINECS | 205-715-3 |
| HTC | 29124900 |
| PubChem ID | 24847429 |
| MDL Number | MFCD00003322 |
| SMILES | COc1cccc(C=O)c1O |
| InChI | 1S/C8H8O3/c1-11-7-4-2-3-6(5-9)8(7)10/h2-5,10H,1H3 |
| InChI Key | JJVNINGBHGBWJH-UHFFFAOYSA-N |
| Beilstein/REAXYS | 471913 |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| MSDS | msds/20984_1_148_53_8.pdf |
| Bioactivity | o-Vanillin (2-Vanillin) is a nature product, could be extracted from Vanilla planifolia, Pinus koraiensis fruit. o-Vanillin is a potent antifungal agent. o-Vanillin inhibits the growth of mycelia by disrupting the integrity of cell walls and cell membranes. o-Vanillin inhibits Doxorubicin (HY-15142A)- and 4-hydroperoxycyclophosphamide-induced NF-κB activation[1][2]. Related Catalog Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal In Vitro o-Vanillin (2-Vanillin; 0-125 μg/mL; 24-72 h) inhibits the mycelial growth of A. flavus in a dose-dependent manner[1]. o-Vanillin (0-100 μg/mL; 48 h; A. flavus) changes the morphology of mycelia and induces irregular shrinkage of the mycelia[1]. o-Vanillin (0-100 μg/mL; A. flavus) decreases the protein content of the cell wall surface and the content of β-1,3-glucan[1]. o-Vanillin (0-100 μg/mL; A. flavus) destroys cell membrane integrity. o-Vanillin releases cell constituents and decreases extracellular pH value[1]. o-Vanillin (0-100 μg/mL) could effectively inhibit the growth of A. flavus on corn kernels[1]. o-Vanillin (0-250 μM) inhibits doxorubicin-mediated induction of NFĸB activity by 65% in A375/NFĸB-Luc cells. o-Vanillin suppresses 4-HC-induced activity by 43%[2]. In Vivo o-Vanillin (2-Vanillin; 60 mg/kg; p.o.; daily, for 5 d) inhibits tumor growth in mice bearing A375 human melanoma xenografts[2]. Animal Model: Male NSG mice with A375 human melanoma xenografts (12-16 weeks of age)[2] Dosage: 60 mg/kg Administration: Oral administration; daily, for 5 days Result: Delayed the growth of A375 human melanoma xenografts in immunodeficient NSG mice. Chemical & Physical Properties Density 1.2±0.1 g/cm3 Boiling Point 265.5±0.0 °C at 760 mmHg Melting Point 40-42 °C(lit.) Molecular Formula C8H8O3 Molecular Weight 152.147 Flash Point 94.0±15.3 °C Exact Mass 152.047348 PSA 46.53000 LogP 1.40 Vapour Pressure 0.0±0.5 mmHg at 25°C Index of Refraction 1.588 InChIKey JJVNINGBHGBWJH-UHFFFAOYSA-N SMILES COc1cccc(C=O)c1O Water Solubility slightly soluble |
| Use of | o-Vanillin (2-Vanillin) is a nature product, could be extracted from Vanilla planifolia, Pinus koraiensis fruit. o-Vanillin is a potent antifungal agent. o-Vanillin inhibits the growth of mycelia by disrupting the integrity of cell walls and cell membranes. o-Vanillin inhibits Doxorubicin (HY-15142A)- and 4-hydroperoxycyclophosphamide-induced NF-κB activation[1][2]. Properties Articles27 Name ortho-vanillin Synonym More Synonyms 3-Methoxysalicylaldehyde Biological Activity Description o-Vanillin (2-Vanillin) is a nature product, could be extracted from Vanilla planifolia, Pinus koraiensis fruit. o-Vanillin is a potent antifungal agent. o-Vanillin inhibits the growth of mycelia by disrupting the integrity of cell walls and cell membranes. o-Vanillin inhibits Doxorubicin (HY-15142A)- and 4-hydroperoxycyclophosphamide-induced NF-κB activation[1][2]. Related Catalog Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Chemical & Physical Properties Molecular Formula C8H8O3 Exact Mass 152.047348 PSA 46.53000 Index of Refraction 1.588 InChIKey JJVNINGBHGBWJH-UHFFFAOYSA-N Water Solubility slightly soluble |
| Tax Rebate | 9.0% |
| Supervision | None. MFN tariff: 5.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 99.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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