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Tetraethylene glycol dimethyl ether structure, CAS 143-24-8

Tetraethylene glycol dimethyl ether

CAS Number143-24-8

Synonymstetraglyme; Dimethyltetraglycol; Bis[2-(2-methoxyethoxy)ethyl] ether; MFCD00008505; 2,5,8,11,14-Pentaoxapentadecane; EINECS 205-594-7; 1-methoxy-2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethane; 2,5,8,11,14-Pentaoxapentadecane (Bis[2-(2-methoxyethoxy)ethyl] ether; Dimethoxytetraethylene glycol; Tetraethylene glycol dimethyl ether

Molecular FormulaCH3O(CH2CH2O)4CH3

Molecular Weight222.28

Purity≥99%

Density1.0±0.1 g/cm3

Boiling Point275-276 °C (lit.)

Melting Point−30 °C (lit.)

Flash Point

Appearanceliquid

EINECS205-594-7

MSDSChineseEnglish

SymbolTransport

Signal WordWarning

Cat. No.: 2A-9020932 Purity: ≥99%
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Quality Control of [ 143-24-8 ] Purity: ≥99% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number143-24-8
Catalog No.2A-9020932
Chinese Name四乙二醇二甲醚
Synonymstetraglyme; Dimethyltetraglycol; Bis[2-(2-methoxyethoxy)ethyl] ether; MFCD00008505; 2,5,8,11,14-Pentaoxapentadecane; EINECS 205-594-7; 1-methoxy-2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethane; 2,5,8,11,14-Pentaoxapentadecane (Bis[2-(2-methoxyethoxy)ethyl] ether; Dimethoxytetraethylene glycol; Tetraethylene glycol dimethyl ether
Molecular FormulaCH3O(CH2CH2O)4CH3
Molecular Weight222.28
Purity≥99
Density1.0±0.1 g/cm3
Boiling Point275-276 °C (lit.)
Melting Point−30 °C (lit.)
Appearanceliquid
Water SolubilitySoluble
Storage ConditionKeep sealed.
ApplicationMe-PEG4-Me is a PROTAC linker, belonging to the PEG class. Can be used to synthesize PROTAC molecules.
EINECS205-594-7
HTC2942000000
PubChem ID24850399
MDL NumberMFCD00008505
SMILESCOCCOCCOCCOCCOC
InChI1S/C10H22O5/c1-11-3-5-13-7-9-15-10-8-14-6-4-12-2/h3-10H2,1-2H3
InChI KeyZUHZGEOKBKGPSW-UHFFFAOYSA-N
Beilstein/REAXYS1760005
NACRES CodeNA.23
UNSPSC12162002
Hazard SymbolsTransport
MSDSmsds/20932_1_143_24_8.pdf
BioactivityMe-PEG4-Me is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker Target PEGs In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Chemical & Physical Properties Density 1.0±0.1 g/cm3 Boiling Point 275.3±0.0 °C at 760 mmHg Melting Point −30 °C(lit.) Molecular Formula C10H22O5 Molecular Weight 222.279 Flash Point 140.6±0.0 °C Exact Mass 222.146729 PSA 46.15000 LogP -1.51 Vapour density 7.7 (vs air) Vapour Pressure 0.0±0.5 mmHg at 25°C Index of Refraction 1.421 InChIKey ZUHZGEOKBKGPSW-UHFFFAOYSA-N SMILES COCCOCCOCCOCCOC
Use ofMe-PEG4-Me is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Properties Articles29 Name tetraglyme Synonym More Synonyms Me-PEG4-Me Biological Activity Description Me-PEG4-Me is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Chemical & Physical Properties Molecular Formula C10H22O5 Exact Mass 222.146729 PSA 46.15000 LogP -1.51 Vapour density 7.7 (vs air) Index of Refraction 1.421 InChIKey ZUHZGEOKBKGPSW-UHFFFAOYSA-N SMILES COCCOCCOCCOCCOC
Tax Rebate9.0%
Supervisionnone
Transport InfoShipping Name: UN
MSDS Transport InfoModule 14. Shipping information 14.1 United Nations number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special precautions No data available
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