CAS Number132-69-4
Synonyms3-(1-benzylindazol-3-yl)oxy-N,N-dimethylpropan-1-amine,hydrochloride; 3-[(1-Benzyl-1H-indazol-3-yl)oxy]-N,N-dimethyl-1-propanamine hydrochloride (1:1); 1-Propanamine, N,N-dimethyl-3-[[1-(phenylmethyl)-1H-indazol-3-yl]oxy]-, hydrochloride (1:1); EINECS 205-076-0; 1-Benzyl-3-[3-(dimethylamino)propoxy]-1H-indazole Hydrochloride; 3-[(1-Benzyl-1H-indazol-3-yl)oxy]-N,N-dimethylpropan-1-amine hydrochloride (1:1); Benzindamine Hydrochloride; BenzydaMine Hydrochloride; MFCD00078957; Benzydamine (hydrochloride)
Molecular FormulaC19H24ClN3O
Molecular Weight345.87
Purity98.00%
Boiling Point474.4ºC at 760 mmHg
Melting Point147-153ºC
Appearancesolid
EINECS205-076-0
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 132-69-4 |
| Catalog No. | 2A-9020692 |
| Chinese Name | 盐酸苄达明 |
| Synonyms | 3-(1-benzylindazol-3-yl)oxy-N,N-dimethylpropan-1-amine,hydrochloride; 3-[(1-Benzyl-1H-indazol-3-yl)oxy]-N,N-dimethyl-1-propanamine hydrochloride (1:1); 1-Propanamine, N,N-dimethyl-3-[[1-(phenylmethyl)-1H-indazol-3-yl]oxy]-, hydrochloride (1:1); EINECS 205-076-0; 1-Benzyl-3-[3-(dimethylamino)propoxy]-1H-indazole Hydrochloride; 3-[(1-Benzyl-1H-indazol-3-yl)oxy]-N,N-dimethylpropan-1-amine hydrochloride (1:1); Benzindamine Hydrochloride; BenzydaMine Hydrochloride; MFCD00078957; Benzydamine (hydrochloride) |
| Molecular Formula | C19H24ClN3O |
| Molecular Weight | 345.87 |
| Purity | 98.00 |
| Boiling Point | 474.4ºC at 760 mmHg |
| Melting Point | 147-153ºC |
| Appearance | solid |
| Water Solubility | Water solubility: soluble |
| Storage Condition | Ventilated, low-temperature drying, stored separat |
| Application | Benzydamine hydrochloride is a prostaglandin synthase inhibitor, anti-inflammatory, and has also been reported to have antibacterial activity. |
| EINECS | 205-076-0 |
| HTC | 2933990090 |
| MDL Number | MFCD00078957 |
| SMILES | Cl.CN(C)CCCOc1nn(Cc2ccccc2)c3ccccc13 |
| InChI | 1S/C19H23N3O.ClH/c1-21(2)13-8-14-23-19-17-11-6-7-12-18(17)22(20-19)15-16-9-4-3-5-10-16;/h3-7,9-12H,8,13-15H2,1-2H3;1H |
| InChI Key | HNNIWKQLJSNAEQ-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | Transport |
| MSDS | msds/20692_1_132_69_4.pdf |
| Bioactivity | Benzydamine Hcl is a locally-acting nonsteroidal anti-inflammatory drug with local anaesthetic and analgesic properties; selectively binds to prostaglandin synthetase and has notable in vitro antibacterial activity. Related Catalog Signaling Pathways >> Immunology/Inflammation >> PGE synthase Research Areas >> Inflammation/Immunology References [1]. Anand JS, et al. Recreational abuse with benzydamine hydrochloride (tantum rosa). Clin Toxicol (Phila). 2007;45(2):198-9. [2]. Opaleye ES, et al. Recreational use of benzydamine as a hallucinogen among street youth in Brazil. Rev Bras Psiquiatr. 2009 Sep;31(3):208-13. [3]. Mota DM, et al. Use abusive of benzydamine in Brazil: an overview in pharmacovigilance. Cien Saude Colet. 2010 May;15(3):717-24. [4]. Fanaki NH, et al. Antimicrobial activity of benzydamine, a non-steroid anti-inflammatory agent. J Chemother. 1992 Dec;4(6):347-52. Chemical & Physical Properties Boiling Point 474.4ºC at 760 mmHg Melting Point 147-153ºC Molecular Formula C19H24ClN3O Molecular Weight 345.866 Flash Point 240.7ºC Exact Mass 345.160797 PSA 30.29000 LogP 4.21710 Vapour Pressure 3.64E-09mmHg at 25°C InChIKey HNNIWKQLJSNAEQ-UHFFFAOYSA-N SMILES CN(C)CCCOc1nn(Cc2ccccc2)c2ccccc12.Cl |
| Use of | Benzydamine Hcl is a locally-acting nonsteroidal anti-inflammatory drug with local anaesthetic and analgesic properties; selectively binds to prostaglandin synthetase and has notable in vitro antibacterial activity. Properties Articles31 Name Benzydamine Hydrochloride Synonym More Synonyms Benzindamine Hydrochloride Biological Activity Description Benzydamine Hcl is a locally-acting nonsteroidal anti-inflammatory drug with local anaesthetic and analgesic properties; selectively binds to prostaglandin synthetase and has notable in vitro antibacterial activity. Related Catalog Signaling Pathways >> Immunology/Inflammation >> PGE synthase Research Areas >> Inflammation/Immunology References [1]. Anand JS, et al. Recreational abuse with benzydamine hydrochloride (tantum rosa). Clin Toxicol (Phila). 2007;45(2):198-9. [2]. Opaleye ES, et al. Recreational use of benzydamine as a hallucinogen among street youth in Brazil. Rev Bras Psiquiatr. 2009 Sep;31(3):208-13. [3]. Mota DM, et al. Use abusive of benzydamine in Brazil: an overview in pharmacovigilance. Cien Saude Colet. 2010 May;15(3):717-24. [4]. Fanaki NH, et al. Antimicrobial activity of benzydamine, a non-steroid anti-inflammatory agent. J Chemother. 1992 Dec;4(6):347-52. Chemical & Physical Properties Exact Mass 345.160797 PSA 30.29000 LogP 4.21710 InChIKey HNNIWKQLJSNAEQ-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 97.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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