| Chemical & Physical Properties | |
|---|---|
| CAS Number | 36804-17-8 |
| Catalog No. | 2A-0202770 |
| Chinese Name | 水飞蓟宾(水飞蓟宾A和水飞蓟宾B的混合物) |
| Synonyms | Silybin; S0508 |
| Molecular Formula | C25H22O10 |
| Molecular Weight | 482.44 |
| Density | 1.527g/cm3 |
| Boiling Point | 793ºC at 760 mmHg |
| Melting Point | 160ºC |
| Appearance | Solid;White to Orange to Green powder to crystaline |
| Storage Condition | Sealed, cool, dry and ventilated storage |
| Application | (±)-Silybin is the racemate of Silybin (HY-N0779A). Silybin induces apoptosis and has hepatoprotective, antioxidant, anti-inflammatory, and anti-cancer activities. |
| PubChem ID | 36416378 |
| InChI | InChI=1S/C25H22O10/c1-32-17-6-11(2-4-14(17)28)24-20(10-26)33-16-5-3-12(7-18(16)34-24)25-23(31)22(30)21-15(29)8-13(27)9-19(21)35-25/h2-9,20,23-29,31H,10H2,1H3/t20?,23-,24?,25+/m0/s1 |
| InChI Key | SEBFKMXJBCUCAI-DBMPWETRSA-N |
| Bioactivity | (±)-Silybin is the racemate of Silybin (HY-N0779A). Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity[1][2]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Others >> Others References [1]. Silvia Zappavigna, et al. Silybin-Induced Apoptosis Occurs in Parallel to the Increase of Ceramides Synthesis and miRNAs Secretion in Human Hepatocarcinoma Cells. Int J Mol Sci. 2019 May 3;20(9):2190. [2]. Runbin Sun, et al. Silybin ameliorates hepatic lipid accumulation and modulates global metabolism in an NAFLD mouse model. Biomed Pharmacother. 2020 Mar;123:109721. Chemical & Physical Properties Density 1.527g/cm3 Boiling Point 793ºC at 760 mmHg Melting Point 160ºC Molecular Formula C25H22O10 Molecular Weight 482.44 Flash Point 274.4ºC Exact Mass 481.11300 PSA 159.05000 LogP 3.38430 Index of Refraction 1.684 Storage condition Freezer |
| Use of | (±)-Silybin is the racemate of Silybin (HY-N0779A). Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity[1][2]. Properties Name (2R,3R)-3,5,7-trihydroxy-2-[3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydrochromen-4-one Synonym More Synonyms Biological Activity Description (±)-Silybin is the racemate of Silybin (HY-N0779A). Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity[1][2]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Others >> Others References [1]. Silvia Zappavigna, et al. Silybin-Induced Apoptosis Occurs in Parallel to the Increase of Ceramides Synthesis and miRNAs Secretion in Human Hepatocarcinoma Cells. Int J Mol Sci. 2019 May 3;20(9):2190. [2]. Runbin Sun, et al. Silybin ameliorates hepatic lipid accumulation and modulates global metabolism in an NAFLD mouse model. Biomed Pharmacother. 2020 Mar;123:109721. Chemical & Physical Properties Molecular Formula C25H22O10 Exact Mass 481.11300 PSA 159.05000 LogP 3.38430 Index of Refraction 1.684 Storage condition Freezer |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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