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(R)-(-)-MEPHENYTOIN structure, CAS 71140-51-7

(R)-(-)-MEPHENYTOIN

CAS Number71140-51-7

Synonyms(r)-(-)-mephenytoin

Molecular FormulaC12H14N2O2

Molecular Weight218.26

Purity

Density1.154g/cm3

Boiling Point

Melting Point137-138ºC

Flash Point

Appearance

EINECS

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Symboltransportation

Signal WordWarning

Cat. No.: 2A-0200759 Purity:
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Quality Control of [ 71140-51-7 ] SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number71140-51-7
Catalog No.2A-0200759
Chinese Name(R)-甲苯妥英
Synonyms(r)-(-)-mephenytoin
Molecular FormulaC12H14N2O2
Molecular Weight218.26
Density1.154g/cm3
Melting Point137-138ºC
Storage Condition2-8°C, dry
Application(R)-mephenytoin ((-)-mephenytoin), the R-enantiomer of mephenytoin. Mephenytoin is an anticonvulsant[1][2].
PubChem ID10238357
MDL NumberC12H14N2O2
SMILESCCC1(c2ccccc2)NC(=O)N(C)C1=O
InChIInChI=1S/C12H14N2O2/c1-3-12(9-7-5-4-6-8-9)10(15)14(2)11(16)13-12/h4-8H,3H2,1-2H3,(H,13,16)/t12-/m1/s1
InChI KeyGMHKMTDVRCWUDX-GFCCVEGCSA-N
Hazard Symbolstransportation
MSDSmsds/202588_1_71140_51_7.pdf
Bioactivity(R)-Mephenytoin ((-)-Mephenytoin), the R-enantiomer of Mephenytoin. Mephenytoin is an Anticonvulsant agent[1][2]. Related Catalog Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Research Areas >> Neurological Disease In Vitro (R)-Mephenytoin can be N-demethylated by the cytochrome P450 (CYP) isoform CYP2C9 to form the metabolite 5-phenyl-5-ethylhydantoin (nirvanol)[1]. References [1]. Meier UT, et, al. Assay of mephenytoin metabolism in human liver microsomes by high-performance liquid chromatography. Anal Biochem. 1985 Dec;151(2):286-91. [2]. Relling MV, et, al. Tolbutamide and mephenytoin hydroxylation by human cytochrome P450s in the CYP2C subfamily. J Pharmacol Exp Ther. 1990 Jan;252(1):442-7. Chemical & Physical Properties Density 1.154g/cm3 Melting Point 137-138ºC Molecular Formula C12H14N2O2 Molecular Weight 218.25200 Exact Mass 218.10600 PSA 49.41000 LogP 1.74020 Index of Refraction 1.541 InChIKey GMHKMTDVRCWUDX-GFCCVEGCSA-N SMILES CCC1(c2ccccc2)NC(=O)N(C)C1=O
Use of(R)-Mephenytoin ((-)-Mephenytoin), the R-enantiomer of Mephenytoin. Mephenytoin is an Anticonvulsant agent[1][2]. Properties Name (R)-Mephenytoin Synonym More Synonyms (R)-Mephenytoin Biological Activity Description (R)-Mephenytoin ((-)-Mephenytoin), the R-enantiomer of Mephenytoin. Mephenytoin is an Anticonvulsant agent[1][2]. Related Catalog Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Research Areas >> Neurological Disease References [1]. Meier UT, et, al. Assay of mephenytoin metabolism in human liver microsomes by high-performance liquid chromatography. Anal Biochem. 1985 Dec;151(2):286-91. Chemical & Physical Properties Molecular Formula C12H14N2O2 Exact Mass 218.10600 PSA 49.41000 LogP 1.74020 Index of Refraction 1.541 InChIKey GMHKMTDVRCWUDX-GFCCVEGCSA-N
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available See reverse side of invoice or packing slip.
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