EN
0
Home > Products > Food & Nutrition > Nutritional Ingredients > Palmitoyl-L-Carnitine Chloride
Palmitoyl-L-Carnitine Chloride structure, CAS 18877-64-0

Palmitoyl-L-Carnitine Chloride

CAS Number18877-64-0

SynonymsMFCD00070346; Palmitoyl-L-carnitine chloride; 3-carboxy-n,n,n-trimethyl-2-(palmitoyloxy)propan-1-aminium chloride; UNII:EIL57224QR; 1-Propanaminium, 3-carboxy-N,N,N-trimethyl-2-[(1-oxohexadecyl)oxy]-, chloride (1:1); EINECS 242-642-6; 3-Carboxy-N,N,N-trimethyl-2-(palmitoyloxy)-1-propanaminium chloride

Molecular FormulaC23H46NO4 · Cl

Molecular Weight436.07

Purity≥98 (TLC)%

Density

Boiling Point

Melting Point168-172ºC(lit.)

Flash Point

Appearancepowder

EINECS242-642-6

MSDSChineseEnglish

Symboltransportation

Signal WordWarning

Cat. No.: 2A-2199669 Purity: ≥98 (TLC)%
Change View

Please Login or Create an Account to: See VlP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

Inquiry

Quality Control of [ 18877-64-0 ] Purity: ≥98 (TLC)% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number18877-64-0
Catalog No.2A-2199669
Chinese Name棕榈酰-L-肉碱盐酸盐
SynonymsMFCD00070346; Palmitoyl-L-carnitine chloride; 3-carboxy-n,n,n-trimethyl-2-(palmitoyloxy)propan-1-aminium chloride; UNII:EIL57224QR; 1-Propanaminium, 3-carboxy-N,N,N-trimethyl-2-[(1-oxohexadecyl)oxy]-, chloride (1:1); EINECS 242-642-6; 3-Carboxy-N,N,N-trimethyl-2-(palmitoyloxy)-1-propanaminium chloride
Molecular FormulaC23H46NO4 · Cl
Molecular Weight436.07
Purity≥98 (TLC)
Melting Point168-172ºC(lit.)
Appearancepowder
Storage ConditionRefrigerated at -20°C, airtight, dry place
ApplicationL-Palmitoylcarnitine chloride is a long-chain acylcarnitine and fatty acid metabolite that accumulates in the muscle membrane during ischemia and disrupts the membrane lipid environment. L-Palmitoylca
EINECS242-642-6
PubChem ID24898229
MDL NumberMFCD00070346
SMILES[Cl-].CCCCCCCCCCCCCCCC(=O)O[C@H](CC(O)=O)C[N+](C)(C)C
InChI1S/C23H45NO4.ClH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(27)28-21(19-22(25)26)20-24(2,3)4;/h21H,5-20H2,1-4H3;1H/t21-;/m1./s1
InChI KeyGAMKNLFIHBMGQT-ZMBIFBSDSA-N
Beilstein/REAXYS4071005
NACRES CodeNA.25
UNSPSC12352211
Hazard Symbolstransportation
MSDSmsds/201659_1_18877_64_0.pdf
BioactivityL-Palmitoylcarnitine chloride, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine chloride inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2[1]. Related Catalog Research Areas >> Cardiovascular Disease Research Areas >> Metabolic Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel Target Kir6.2 Human Endogenous Metabolite In Vitro L-Palmitoylcarnitine (1 µM) inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2. L-Palmitoylcarnitine simultaneously enhances the ATP sensitivity of the channel (IC50 fell from 62 to 30 µM)[1]. Modulation of the membrane lipid environment caused by L-Palmitoylcarnitine alters the KATP channel function mainly through the interaction with endogenous PI cascade, especially PIP2[1]. References [1]. Haruna T, et al. Alteration of the membrane lipid environment by L-palmitoylcarnitine modulates K(ATP) channels in guinea-pig ventricular myocytes. Pflugers Arch. 2000;441(2-3):200-207. Chemical & Physical Properties Melting Point 168-172ºC(lit.) Molecular Formula C23H46ClNO4 Molecular Weight 436.069 Exact Mass 435.311523 PSA 63.60000 LogP 2.56440 InChIKey GAMKNLFIHBMGQT-ZMBIFBSDSA-N SMILES CCCCCCCCCCCCCCCC(=O)OC(CC(=O)O)C[N+](C)(C)C.[Cl-] Storage condition -20°C
Use ofL-Palmitoylcarnitine chloride, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine chloride inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2[1]. Properties Name palmitoyl-l-carnitine chloride Synonym More Synonyms L-Palmitoylcarnitine chloride Biological Activity Description L-Palmitoylcarnitine chloride, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine chloride inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2[1]. Related Catalog Research Areas >> Cardiovascular Disease Research Areas >> Metabolic Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel Human Endogenous Metabolite References [1]. Haruna T, et al. Alteration of the membrane lipid environment by L-palmitoylcarnitine modulates K(ATP) channels in guinea-pig ventricular myocytes. Pflugers Arch. 2000;441(2-3):200-207. Chemical & Physical Properties Exact Mass 435.311523 PSA 63.60000 LogP 2.56440 InChIKey GAMKNLFIHBMGQT-ZMBIFBSDSA-N SMILES CCCCCCCCCCCCCCCC(=O)OC(CC(=O)O)C[N+](C)(C)C.[Cl-]
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available
Related Products in Nutritional Ingredients
YEAST BETA-GLUCAN9051-09-22A-1199551
BETA-GLUCAN160872-27-52A-1199552
LAUROYL-L-CARNITINE CHLORIDE6919-91-12A-1199576
Chlorella2A-21996172A-2199617
Whey protein isolate2A-21996372A-2199637
Conjugated linoleic acid22880-03-12A-2199674
N-ACETYL-ALPHA-D-GLUCOSAMINE 6-PHOSPHATE DISODIUM SALT31281-59-12A-2199798
L-Glutamic acid, N-[4-[(2-amino-3,4-dihydro-7-methyl-4-oxo-6-pteridinyl)amino]benzoyl]-2734707-85-62A-1199921
kasugamycin 2%+tricyclazole 20%WP19408-46-9+41814-78-22A-2200002
epoxiconazole 6%+tricyclazole 24%SC135319-73-2+41814-78-22A-2200004
Browse all Nutritional Ingredients products »
Contact Us

Phone:

630-322-8886

630-322-8887

Email:

[email protected]

Office Locations:

Chicago, IL, USA

San Francisco, CA, USA