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Home > Products > Natural Products & Standards > Botanical Reference Standards > 2'-Hydroxy-4,4',6'-trimethoxychalcone
2'-Hydroxy-4,4',6'-trimethoxychalcone structure, CAS 3420-72-2

2'-Hydroxy-4,4',6'-trimethoxychalcone

CAS Number3420-72-2

SynonymsFLAVOKAWIN A; 1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one; Flavokavin A; MFCD00017174; 2'-Hydroxy-4,4',6'-trimethoxy-trans-chalcone; 2'-Hydroxy-4,4',6'-trimethoxy; flavokawain-A; 2'-hydroxy-4',6'-dimethoxyphenyl-4-methoxystyrylketone; 2'-hydroxy-4,4',6'-trimethoxy-chalcone; Flavokawain A

Molecular FormulaCH3OC6H4CH=CHCOC6H2(OCH3)2OH

Molecular Weight314.33

Purity98%

Density1.2±0.1 g/cm3

Boiling Point529.9±50.0 °C at 760 mmHg

Melting Point112-116 °C (lit.)

Flash Point

Appearancesolid

EINECS

MSDSChineseEnglish

Symboltransportation

Signal WordWarning

Cat. No.: 2A-2199490 Purity: 98%
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Quality Control of [ 3420-72-2 ] Purity: 98% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number3420-72-2
Catalog No.2A-2199490
Chinese Name黄卡瓦胡椒素A; 2'- 羟基-4,4',6'-三甲氧基查耳酮
SynonymsFLAVOKAWIN A; 1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one; Flavokavin A; MFCD00017174; 2'-Hydroxy-4,4',6'-trimethoxy-trans-chalcone; 2'-Hydroxy-4,4',6'-trimethoxy; flavokawain-A; 2'-hydroxy-4',6'-dimethoxyphenyl-4-methoxystyrylketone; 2'-hydroxy-4,4',6'-trimethoxy-chalcone; Flavokawain A
Molecular FormulaCH3OC6H4CH=CHCOC6H2(OCH3)2OH
Molecular Weight314.33
Purity98
Density1.2±0.1 g/cm3
Boiling Point529.9±50.0 °C at 760 mmHg
Melting Point112-116 °C (lit.)
Appearancesolid
Storage ConditionStore in a cool and ventilated place
ApplicationFlavokawain A is an anticarcinogenic agent, a chalcone in kava extract, with antitumor activity. Flavokawain A induces apoptosis through Bax protein-dependent and mitochondria-dependent apoptotic path
HTC2914509090
PubChem ID24879749
MDL NumberMFCD00017174
SMILESCOc1ccc(\C=C\C(=O)c2c(O)cc(OC)cc2OC)cc1
InChI1S/C18H18O5/c1-21-13-7-4-12(5-8-13)6-9-15(19)18-16(20)10-14(22-2)11-17(18)23-3/h4-11,20H,1-3H3/b9-6+
InChI KeyCGIBCVBDFUTMPT-RMKNXTFCSA-N
NACRES CodeNA.22
UNSPSC12352100
Hazard Symbolstransportation
MSDSmsds/201468_1_3420_72_2.pdf
BioactivityFlavokawain A, a proming anticarcinogenic agent, is a chalcone from kava extract with anti-tumor activity. Flavokawain A induces cell apoptosis by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway. Flavokawain A has the potential for the study of bladder cancer[1]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer References [1]. Xiaolin Zi, et al. Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice. Cancer Res. 2005 Apr 15;65(8):3479-86. Chemical & Physical Properties Density 1.2±0.1 g/cm3 Boiling Point 529.9±50.0 °C at 760 mmHg Melting Point 112-116 °C(lit.) Molecular Formula C18H18O5 Molecular Weight 314.332 Flash Point 193.2±23.6 °C Exact Mass 314.115417 PSA 64.99000 LogP 3.96 Vapour Pressure 0.0±1.4 mmHg at 25°C Index of Refraction 1.600
Use ofFlavokawain A, a proming anticarcinogenic agent, is a chalcone from kava extract with anti-tumor activity. Flavokawain A induces cell apoptosis by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway. Flavokawain A has the potential for the study of bladder cancer[1]. Properties Name 2'-hydroxy-4,4',6'-trimethoxychalcone Synonym More Synonyms Flavokawain A Biological Activity Description Flavokawain A, a proming anticarcinogenic agent, is a chalcone from kava extract with anti-tumor activity. Flavokawain A induces cell apoptosis by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway. Flavokawain A has the potential for the study of bladder cancer[1]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer References [1]. Xiaolin Zi, et al. Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice. Cancer Res. 2005 Apr 15;65(8):3479-86. Chemical & Physical Properties Molecular Formula C18H18O5 Exact Mass 314.115417 PSA 64.99000 Index of Refraction 1.600
Tax Rebate9.0%
SupervisionNone MFN tariff: 5.5% Ordinary tariff: 30.0%
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available
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