| Chemical & Physical Properties | |
|---|---|
| CAS Number | 81836-43-3 |
| Catalog No. | 2A-1198491 |
| Chinese Name | 4,7,10,13,16-五氧杂十七烷酸 |
| Synonyms | 4,7,10,13,16-Pentaoxaheptadecanoic acid |
| Molecular Formula | C12H24O7 |
| Molecular Weight | 280.32 |
| Appearance | liquid |
| Storage Condition | 2~8℃, dry, sealed |
| Application | m-PEG5-acid is a PEG-based PROTAC linker that can be used for PROTAC synthesis. |
| MDL Number | MFCD20926398 |
| SMILES | COCCOCCOCCOCCOCCC(=O)O |
| InChI Key | KTTNUZHOERZAMX-UHFFFAOYSA-N |
| MSDS | msds/200399_1_81836_43_3.pdf |
| Bioactivity | m-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. References [1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67. Chemical & Physical Properties Molecular Formula C12H24O7 Molecular Weight 280.31500 Exact Mass 280.15200 PSA 83.45000 LogP 0.17390 InChIKey KTTNUZHOERZAMX-UHFFFAOYSA-N SMILES COCCOCCOCCOCCOCCC(=O)O |
| Use of | m-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Properties Name 2,5,8,11,14-pentaoxaheptadecan-17-oic acid Synonym More Synonyms m-PEG5-acid Biological Activity Description m-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. References [1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67. Chemical & Physical Properties Molecular Formula C12H24O7 Exact Mass 280.15200 PSA 83.45000 LogP 0.17390 InChIKey KTTNUZHOERZAMX-UHFFFAOYSA-N SMILES COCCOCCOCCOCCOCCC(=O)O |
| Transport Info | Product name: 4,7,10,13,16-Pentaoxaheptadecanoic acid |
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