CAS Number15991-13-6
Synonymsmethyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate; methyl (7-hydroxy-2-oxo-2H-chromen-4-yl)acetate; (7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid methyl ester; 7-hydroxy-4-methoxycarbonylmethyl-2H-chromen-2-one; methyl 2-(7-hydroxy-2-oxochromen-4-yl) acetate; (7'-hydroxycoumarin-4-yl)acetic acid methyl ester; 7-hydroxycoumarin-4-acetic acid methyl ester
Molecular FormulaC12H10O5
Molecular Weight234.21
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 15991-13-6 |
| Catalog No. | 2A-1197583 |
| Chinese Name | Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate |
| Synonyms | methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate; methyl (7-hydroxy-2-oxo-2H-chromen-4-yl)acetate; (7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid methyl ester; 7-hydroxy-4-methoxycarbonylmethyl-2H-chromen-2-one; methyl 2-(7-hydroxy-2-oxochromen-4-yl) acetate; (7'-hydroxycoumarin-4-yl)acetic acid methyl ester; 7-hydroxycoumarin-4-acetic acid methyl ester |
| Molecular Formula | C12H10O5 |
| Molecular Weight | 234.21 |
| Application | Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate is a natural coumarin derivative, synthesized as a switchable fluorescent substrate for bacterial enzyme detection. |
| HTC | 2932209090 |
| PubChem ID | 3535013 |
| MDL Number | C12H10O5 |
| SMILES | COC(=O)Cc1cc(=O)oc2cc(O)ccc12 |
| InChI | InChI=1S/C12H10O5/c1-16-11(14)4-7-5-12(15)17-10-6-8(13)2-3-9(7)10/h2-3,5-6,13H,4H2,1H3 |
| InChI Key | YRNMDWOVAZLMDY-UHFFFAOYSA-N |
| MSDS | msds/199426_1_15991_13_6.pdf |
| Use of | Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate, a natural coumarins derivative, is exploited for the synthesis of the switchable fluorescent substrates to be used in bacterial enzyme detection[1][2][3]. Properties Name methyl 2-(7-hydroxy-2-oxochromen-4-yl)acetate Synonym More Synonyms Biological Activity Description Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate, a natural coumarins derivative, is exploited for the synthesis of the switchable fluorescent substrates to be used in bacterial enzyme detection[1][2][3]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others In Vitro Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate (compound 2) exhibits the maximum absorption (λabs~322 nm) and emission (λem~387 nm) wavelengths[2]. References [1]. Nascimento JSD, et al. Mapping the Biotransformation of Coumarins through Filamentous Fungi. Molecules. 2019 Sep 29;24(19). [2]. Lizzul-Jurse A, et al. Readily functionalizable phosphonium-tagged fluorescent coumarins for enhanced detection of conjugates by mass spectrometry. Org Biomol Chem. 2016 Aug 10;14(32):7777-91. [3]. Giovannini G, et al. Coumarin-based, switchable fluorescent substrates for enzymatic bacterial detection. Talanta. 2018 Oct 1;188:448-453. Chemical & Physical Properties Molecular Formula C12H10O5 Exact Mass 234.05300 PSA 76.74000 LogP 1.21410 InChIKey YRNMDWOVAZLMDY-UHFFFAOYSA-N Safety Information HS Code 2932209090 Synthetic Route CAS#:67-56-1 2H-1-Benzopyran... CAS#:6950-82-9 Methyl 2-(7-hyd... CAS#:15991-13-6 Literature: Holmes, Christopher P.; Macher, Natalie; Grove, J. Russell; Jang, Larry; Irvine, Jennifer D. Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 11 p. 3382 - 3385 Dimethyl 3-oxog... CAS#:1830-54-2 CAS#:108-46-3 Methyl 2-(7-hyd... CAS#:15991-13-6 Literature: Smitha; Reddy, Ch. Sanjeeva Synthetic Communications, 2004 , vol. 34, # 21 p. 3997 - 4003 Dimethyl 3-oxog... CAS#:1830-54-2 CAS#:108-46-3 Methyl 2-(7-hyd... CAS#:15991-13-6 trans cyclobuta... CAS#:780821-74-1 Literature: Dubovik; Garazd; Khilya Chemistry of Heterocyclic Compounds, 2007 , vol. 43, # 3 p. 277 - 281 Precursor & DownStream Precursor 7 CAS#:67-56-1 CAS#:6950-82-9 2H-1-Benzopyran... CAS#:1830-54-2 Dimethyl 3-oxog... CAS#:108-46-3 DownStream 6 CAS#:62935-72-2 (7-Methoxy-2-ox... CAS#:6950-82-9 2H-1-Benzopyran... CAS#:127615-74-1 2-[2-oxo-7-[(2S... CAS#:127615-75-2 7-beta-galactop... |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| Related Products in Specialty & Botanical Ingredients | ||
|---|---|---|
| White kidney bean extract 1% coumarin | 2A-2195939 | 2A-2195939 |
| 3,3'-CARBONYLBIS(7-DIETHYLAMINOCOUMARIN) | 63226-13-1 | 2A-1196007 |
| 2-NITROCINNAMALDEHYDE | 66894-06-2 | 2A-2196901 |
| 4-Methyl-5,7-dimethoxycoumarin | 6093-80-7 | 2A-2196902 |
| 2-NITROCINNAMALDEHYDE | 1466-88-2 | 2A-2196911 |
| 3,3'-CARBONYLBIS(7-METHOXYCOUMARIN) | 64267-17-0 | 2A-1197627 |
| 6,7-DihydroxycouMarin-3-carboxylic Acid | 84738-35-2 | 2A-1197635 |
| di(4-t-butylphenyl)iodonium camphorsulfonate | 193345-23-2 | 2A-1198080 |
| Coumarin-6-carboxylic acid | 7734-80-7 | 2A-1198775 |
| Cineole | 406-67-7 | 2A-2198875 |
| Browse all Specialty & Botanical Ingredients products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS