CAS Number2564-35-4
Synonymsdeoxyguanosinetriphosphate; 2'-deoxy-GTP; 5'-deoxyguanosine triphosphate; DGTP LI-SALT; deoxy-gtp; 5'-DGTP; 2'-DEOXYGUANOSINE-5'-TRIPHOSPHORIC ACID, DISODIUM; DGTP,LI; DGTP,NA2H2; 2'-Deoxyguanosine 5'-(Tetrahydrogen Triphosphate); EINECS 219-887-2
Molecular FormulaC10H16N5O13P3
Molecular Weight511.12
Purity≥99%
Density2.63g/cm3
Boiling Point989.5ºC at 760 mmHg
Appearanceliquid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 2564-35-4 |
| Catalog No. | 2A-1197243 |
| Chinese Name | 2′-脱氧鸟苷 5′-(四氢三磷酸酯) |
| Synonyms | deoxyguanosinetriphosphate; 2'-deoxy-GTP; 5'-deoxyguanosine triphosphate; DGTP LI-SALT; deoxy-gtp; 5'-DGTP; 2'-DEOXYGUANOSINE-5'-TRIPHOSPHORIC ACID, DISODIUM; DGTP,LI; DGTP,NA2H2; 2'-Deoxyguanosine 5'-(Tetrahydrogen Triphosphate); EINECS 219-887-2 |
| Molecular Formula | C10H16N5O13P3 |
| Molecular Weight | 511.12 |
| Purity | ≥99 |
| Density | 2.63g/cm3 |
| Boiling Point | 989.5ºC at 760 mmHg |
| Appearance | liquid |
| Storage Condition | -20°C, sealed, dry |
| Application | dGTP (2'-deoxyguanosine-5'-triphosphate) is a guanosine nucleotide that can be used in the synthesis of DNA. Guanosine nucleotides (GDP, GTP, dGDP and dGTP) are highly sensitive to oxidative damage to |
| PubChem ID | 24893907 |
| MDL Number | MFCD00084683 |
| SMILES | [Na+].[Na+].NC1=NC(=O)N(C=C1)[C@H]2C[C@H](O)[C@@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)O2 |
| InChI | 1S/C9H16N3O13P3.2Na/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(23-8)4-22-27(18,19)25-28(20,21)24-26(15,16)17;;/h1-2,5-6,8,13H,3-4H2,(H,18,19)(H,20,21)(H2,10,11,14)(H2,15,16,17);;/q;2*+1/p-2/t5-,6+,8+;;/m0../s1 |
| InChI Key | ABWVCNMFYVEBIB-CDNBRZBRSA-L |
| NACRES Code | NA.52 |
| UNSPSC | 41106305 |
| MSDS | msds/199071_1_2564_35_4.pdf |
| Bioactivity | dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP[1]. Related Catalog Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog References [1]. Kapoor I, et al. Nucleoside Diphosphate Kinase Escalates A-to-C Mutations in MutT-Deficient Strains of Escherichia coli. J Bacteriol. 2019;202(1):e00567-19. Published 2019 Dec 6. Chemical & Physical Properties Density 2.63g/cm3 Boiling Point 989.5ºC at 760 mmHg Molecular Formula C10H16N5O13P3 Molecular Weight 507.18 Flash Point 552.2ºC PSA 313.96000 LogP 0.15110 Vapour Pressure 0mmHg at 25°C Index of Refraction 1.904 InChIKey HAAZLUGHYHWQIW-KVQBGUIXSA-N SMILES Nc1nc2c(ncn2C2CC(O)C(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]1 |
| Use of | dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP[1]. Properties Synonym More Synonyms Biological Activity Description dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP[1]. Related Catalog Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog References [1]. Kapoor I, et al. Nucleoside Diphosphate Kinase Escalates A-to-C Mutations in MutT-Deficient Strains of Escherichia coli. J Bacteriol. 2019;202(1):e00567-19. Published 2019 Dec 6. Chemical & Physical Properties Molecular Formula C10H16N5O13P3 PSA 313.96000 LogP 0.15110 Index of Refraction 1.904 InChIKey HAAZLUGHYHWQIW-KVQBGUIXSA-N |
| Transport Info | Product name: 2'-deoxyguanosine 5'-triphosphate [dGTP] trisodium salt (aqueous solution) |
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