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Home > Products > Specialty & Industrial Chemicals > Specialty Chemicals > N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE
N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE structure, CAS 132172-61-3

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE

CAS Number132172-61-3

Synonyms2,3-dioleyloxypropyltrimethylammonium chloride; 1,2-dioleoyl-3-trimethylammonium-propane chloride; 1,2-dioleoyl-3-trimethylammonium-propane chloride salt; DOTAP chloride

Molecular FormulaC42H80ClNO4

Molecular Weight698.54

Purity>99 (TLC)%

Density

Boiling Point

Melting Point35-38ºC

Flash Point

Appearancepowder

EINECS

MSDSChineseEnglish

Symboltransportation

Signal WordWarning

Cat. No.: 2A-2197205 Purity: >99 (TLC)%
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Quality Control of [ 132172-61-3 ] Purity: >99 (TLC)% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number132172-61-3
Catalog No.2A-2197205
Chinese Name(2,3-二油酰基-丙基)-三甲胺(氯盐)DOTAP
Synonyms2,3-dioleyloxypropyltrimethylammonium chloride; 1,2-dioleoyl-3-trimethylammonium-propane chloride; 1,2-dioleoyl-3-trimethylammonium-propane chloride salt; DOTAP chloride
Molecular FormulaC42H80ClNO4
Molecular Weight698.54
Purity>99 (TLC)
Melting Point35-38ºC
Appearancepowder
Storage Condition-20℃, protected from light, sealed and dry
ApplicationDOTAP chloride is a highly efficient cationic lipid for transient or stable transfection of DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) without the use of auxiliary
PubChem ID16739264
MDL NumberMFCD01310872
SMILES[H]C(C[N+](C)(C)C)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Cl-]
InChI1S/C42H80NO4.ClH/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-41(44)46-39-40(38-43(3,4)5)47-42(45)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;/h20-23,40H,6-19,24-39H2,1-5H3;1H/q+1;/p-1/b22-20-,23-21-;
InChI KeyKSXTUUUQYQYKCR-LQDDAWAPSA-M
NACRES CodeNA.25
UNSPSC12352211
Hazard Symbolstransportation
MSDSmsds/199030_1_132172_61_3.pdf
BioactivityDOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid[1]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others Target IC50: Cationic Lipid[1] In Vitro liposomes are reorganized by associating with DNA. The transfection efficiency of DOTAP liposomes is mainly influenced by lipid composition and cell type, but not by size or zeta potential[1]. References [1]. Kim BK, et al. DOTAP/DOPE ratio and cell type determine transfection efficiency with DOTAP-liposomes.Biochim Biophys Acta. 2015 Oct;1848(10 Pt A):1996-2001. Chemical & Physical Properties Melting Point 35-38ºC Molecular Formula C42H80ClNO4 Molecular Weight 663.08900 Exact Mass 662.60900 PSA 52.60000 LogP 12.22260 InChIKey KSXTUUUQYQYKCR-LQDDAWAPSA-M SMILES CCCCCCCCC=CCCCCCCCC(=O)OCC(C[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC.[Cl-]
Use ofDOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid[1]. Properties Name 2,3-di(octadec-9-enoyloxy)propyl-trimethylazanium Synonym More Synonyms DOTAP chloride Biological Activity Description DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid[1]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others IC50: Cationic Lipid[1] In Vitro liposomes are reorganized by associating with DNA. The transfection efficiency of DOTAP liposomes is mainly influenced by lipid composition and cell type, but not by size or zeta potential[1]. References [1]. Kim BK, et al. DOTAP/DOPE ratio and cell type determine transfection efficiency with DOTAP-liposomes.Biochim Biophys Acta. 2015 Oct;1848(10 Pt A):1996-2001. Chemical & Physical Properties Exact Mass 662.60900 PSA 52.60000 LogP 12.22260 InChIKey KSXTUUUQYQYKCR-LQDDAWAPSA-M SMILES CCCCCCCCC=CCCCCCCCC(=O)OCC(C[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC.[Cl-]
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available
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