![2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL structure, CAS 86520-52-7](/structures/210000/198361_1_86520_52_7.png)
CAS Number86520-52-7
Synonyms2-(2-(2-AZIDOETHOXY)ETHOXY)ETHANOL; N3-EEET-OH; 8-azido-3,6-dioxa-1-octanol; 1-Azido-8-hydroxy-3,6-dioxaoctane; Azido-PEG3; 8-Azido-3,6-dioxaoctanol solution; azidotriethylene glycol; 8-Azido-3,6-dioxaoctanol; 8-azido-3,6-dioxaoctan-1-ol
Molecular FormulaC6H13N3O3
Molecular Weight175.19
Purity≥95.0 (GC)%
Appearanceliquid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 86520-52-7 |
| Catalog No. | 2A-1196584 |
| Chinese Name | 叠氮-三聚乙二醇 |
| Synonyms | 2-(2-(2-AZIDOETHOXY)ETHOXY)ETHANOL; N3-EEET-OH; 8-azido-3,6-dioxa-1-octanol; 1-Azido-8-hydroxy-3,6-dioxaoctane; Azido-PEG3; 8-Azido-3,6-dioxaoctanol solution; azidotriethylene glycol; 8-Azido-3,6-dioxaoctanol; 8-azido-3,6-dioxaoctan-1-ol |
| Molecular Formula | C6H13N3O3 |
| Molecular Weight | 175.19 |
| Purity | ≥95.0 (GC) |
| Appearance | liquid |
| Storage Condition | -20°C Freezer |
| Application | Azido-PEG3-alcohol is a PROTAC linker, which belongs to the PEG class and can be used to synthesize PROTAC. |
| HTC | 2929909090 |
| PubChem ID | 329764318 |
| MDL Number | MFCD09753542 |
| SMILES | OCCOCCOCCN=[N+]=[N-] |
| InChI | 1S/C6H13N3O3/c7-9-8-1-3-11-5-6-12-4-2-10/h10H,1-6H2 |
| InChI Key | PMNIHDBMMDOUPD-UHFFFAOYSA-N |
| Beilstein/REAXYS | 4418543 |
| NACRES Code | NA.22 |
| UNSPSC | 12352200 |
| Hazard Symbols | transportation |
| MSDS | msds/198361_1_86520_52_7.pdf |
| Bioactivity | Azido-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker Target PEGs In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228. Chemical & Physical Properties Molecular Formula C6H13N3O3 Molecular Weight 175.18600 Flash Point -33℃ Exact Mass 175.09600 PSA 88.44000 InChIKey PMNIHDBMMDOUPD-UHFFFAOYSA-N SMILES [N-]=[N+]=NCCOCCOCCO Storage condition -20°C Freezer |
| Use of | Azido-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Properties Name 2-[2-(2-Azidoethoxy)ethoxy]ethanol Synonym More Synonyms Azido-PEG3-alcohol Biological Activity Description Azido-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228. Chemical & Physical Properties Molecular Formula C6H13N3O3 Exact Mass 175.09600 PSA 88.44000 InChIKey PMNIHDBMMDOUPD-UHFFFAOYSA-N SMILES [N-]=[N+]=NCCOCCOCCO |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 95.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Danger Regulations: 2398 International Maritime Transport Danger Regulations: 2398 International Air Transport Danger Regulations: 2398 14.2 Names specified by the United Nations (UN) European Land Transport Hazardous Regulations: METHYL tert-BUTYL ETHER, solution IMDG Code: METHYL tert-BUTYL ETHER, solution International Air Transport Risk Regulations: Methyl tert-butyl ether, solution 14.3 Transport hazard categories European land transport Dangerous Regulations: 3 International sea transport Dangerous Regulations: 3 International air transport Dangerous Regulations: 3 14.4 Package group European Dangerous Regulations for land transport: II International Dangerous Regulations for sea transport: II International Dangerous Regulations for air transport: II 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available The above information is believed to be correct, but is not all-inclusive and should be used as a guide only. The information in this document is based on our current knowledge and is Correct safety instructions apply to this product. This information does not represent a warranty as to the properties of this product. See reverse side of invoice or packing slip. |
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