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Home > Products > Specialty & Industrial Chemicals > Specialty Chemicals > 15-Azido-4,7,10,13-tetraoxapentadecanoic acid
15-Azido-4,7,10,13-tetraoxapentadecanoic acid structure, CAS 1257063-35-6

15-Azido-4,7,10,13-tetraoxapentadecanoic acid

CAS Number1257063-35-6

SynonymsAmbotzPEG2345; 15-AZIDO-4,7,10,13-TETRAOXA-PENTADECANOIC ACID; Azido-PEG4-acid

Molecular FormulaC11H21N3O6

Molecular Weight291.30

Purity>90%

Density

Boiling Point

Melting Point

Flash Point

Appearancesolid or viscous liquid

EINECS

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Cat. No.: 2A-1196573 Purity: >90%
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Quality Control of [ 1257063-35-6 ] Purity: >90% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number1257063-35-6
Catalog No.2A-1196573
Chinese Name15-叠氮基-4,7,10,13-四氧杂十五烷酸
SynonymsAmbotzPEG2345; 15-AZIDO-4,7,10,13-TETRAOXA-PENTADECANOIC ACID; Azido-PEG4-acid
Molecular FormulaC11H21N3O6
Molecular Weight291.30
Purity>90
Appearancesolid or viscous liquid
Storage Condition-20°C; store under inert gas; avoid light, moistur
ApplicationAzido-PEG4-C2-acid is a PEG-based PROTAC bridge that can be used to synthesize vRucaparib-TP4. Azido-PEG4-C2-acid is also a non-cleavable ADC linker containing 4 units of PEG, which can be used to syn
PubChem ID329823931
MDL NumberMFCD12406155
SMILESOC(CCOCCOCCOCCOCCN=[N+]=[N-])=O
InChI1S/C11H21N3O6/c12-14-13-2-4-18-6-8-20-10-9-19-7-5-17-3-1-11(15)16/h1-10H2,(H,15,16)
InChI KeyBODPHGOBXPGJKO-UHFFFAOYSA-N
NACRES CodeNA.22
UNSPSC12352106
MSDSmsds/198350_1_1257063_35_6.pdf
BioactivityAzido-PEG4-C2-acid a PEG-based PROTAC linker can be used in the synthesis of vRucaparib-TP4. Azido-PEG4-C2-acid is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Related Catalog Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Research Areas >> Inflammation/Immunology Signaling Pathways >> PROTAC >> PROTAC Linker In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. References [1]. Wang S, et al. Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation. Nat Chem Biol. 2019 Dec;15(12):1223-1231. Chemical & Physical Properties Molecular Formula C11H21N3O6 Molecular Weight 291.30100 Exact Mass 291.14300 PSA 123.97000 LogP 0.29056
Use ofAzido-PEG4-C2-acid a PEG-based PROTAC linker can be used in the synthesis of vRucaparib-TP4. Azido-PEG4-C2-acid is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Properties Name 3-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]propanoic acid Synonym More Synonyms Azido-PEG4-C2-acid Biological Activity Description Azido-PEG4-C2-acid a PEG-based PROTAC linker can be used in the synthesis of vRucaparib-TP4. Azido-PEG4-C2-acid is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Related Catalog Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Research Areas >> Inflammation/Immunology Signaling Pathways >> PROTAC >> PROTAC Linker In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. References [1]. Wang S, et al. Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation. Nat Chem Biol. 2019 Dec;15(12):1223-1231. Chemical & Physical Properties Molecular Formula C11H21N3O6 Exact Mass 291.14300 PSA 123.97000 LogP 0.29056
Transport InfoProduct name: 15-azido-4,7,10,13-tetraoxapentadecanoic acid
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