
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 183320-51-6 |
| Catalog No. | 2A-1196524 |
| Chinese Name | 盐酸厄诺替尼 |
| Synonyms | OSI-420; 2-({4-[(3-Ethynylphenyl)amino]-7-(2-methoxyethoxy)-6-quinazolinyl}oxy)ethanol hydrochloride (1:1); Desmethyl erlotinib hydrochloride; S2205_Selleck; Desmethyl Erlotinib |
| Molecular Formula | C21H22ClN3O4 |
| Molecular Weight | 415.88 |
| Appearance | powder |
| Storage Condition | -20℃ |
| Application | Desmethyl Erlotinib (OSI-420) is the active metabolite of erlotinib, an inhibitor of epidermal growth factor receptor tyrosine kinase (EGFR tyrosin kinase). |
| PubChem ID | 31468928 |
| MDL Number | C21H21N3O4·HCl |
| SMILES | C#Cc1cccc(Nc2ncnc3cc(OCCOC)c(OCCO)cc23)c1.Cl |
| InChI | InChI=1S/C21H21N3O4.ClH/c1-3-15-5-4-6-16(11-15)24-21-17-12-19(27-8-7-25)20(28-10-9-26-2)13-18(17)22-14-23-21;/h1,4-6,11-14,25H,7-10H2,2H3,(H,22,23,24);1H |
| InChI Key | BUOXOWNQZVIETJ-UHFFFAOYSA-N |
| MSDS | msds/198293_1_183320_51_6.pdf |
| Transport Info | Product name: OSI-420 |
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