CAS Number2441-41-0
SynonymsN-Ethanoyl-Hexadecanamide; PALGLY; N-hexadecanoyl glycine; Palmitoylglycine; N-palmitatoylglycyne; N-(1-Oxohexadecyl)glycine; N-Hexadecanoylglycine; Hexadecanoylaminoacetic acid N-palmitoyl glycine; Hexadecanoylaminoacetic acid,N-palmitoyl glycine; 2-(Hexadecanoylamino)acetic acid; N-palmitoyl glycine; N-Palmitoylglycine
Molecular FormulaC18H35NO3
Molecular Weight313.48
Purity≥98 (HPLC)%
Density1.0±0.1 g/cm3
Boiling Point491.8±28.0 °C at 760 mmHg
Appearancesolid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 2441-41-0 |
| Catalog No. | 2A-1195646 |
| Chinese Name | 棕榈酰甘氨酸 |
| Synonyms | N-Ethanoyl-Hexadecanamide; PALGLY; N-hexadecanoyl glycine; Palmitoylglycine; N-palmitatoylglycyne; N-(1-Oxohexadecyl)glycine; N-Hexadecanoylglycine; Hexadecanoylaminoacetic acid N-palmitoyl glycine; Hexadecanoylaminoacetic acid,N-palmitoyl glycine; 2-(Hexadecanoylamino)acetic acid; N-palmitoyl glycine; N-Palmitoylglycine |
| Molecular Formula | C18H35NO3 |
| Molecular Weight | 313.48 |
| Purity | ≥98 (HPLC) |
| Density | 1.0±0.1 g/cm3 |
| Boiling Point | 491.8±28.0 °C at 760 mmHg |
| Appearance | solid |
| Water Solubility | DMSO: >10mg/mL |
| Storage Condition | 2-8°C |
| Application | Palmitoylglycine is a novel endogenous lipid that acts as a modulator of calcium influx and nitric oxide production in sensory neurons. Palmitoylglycine induces a transient calcium influx via calcium- |
| HTC | 2924199090 |
| PubChem ID | 329820003 |
| MDL Number | MFCD00153471 |
| SMILES | O=C(CCCCCCCCCCCCCCC)NCC(O)=O |
| InChI | 1S/C18H35NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17(20)19-16-18(21)22/h2-16H2,1H3,(H,19,20)(H,21,22) |
| InChI Key | KVTFEOAKFFQCCX-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| Hazard Symbols | transportation |
| MSDS | msds/197364_1_2441_41_0.pdf |
| Bioactivity | Palmitoylglycine, a novel endogenous lipid, acts as a modulator of calcium influx and nitric oxide production in sensory neurons. Palmitoylglycine induces transient influx of calcium followed by nitric oxide production via calcium-sensitive nitric-oxide synthase enzymes. Palmitoylglycine potently inhibits heat-evoked firing of nociceptive neurons in rat dorsal horn[1]. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Signaling Pathways >> Immunology/Inflammation >> NO Synthase Research Areas >> Neurological Disease References [1]. Neta Rimmerman, et al. N-palmitoyl glycine, a novel endogenous lipid that acts as a modulator of calcium influx and nitric oxide production in sensory neurons. Mol Pharmacol. 2008 Jul;74(1):213-24. Chemical & Physical Properties Density 1.0±0.1 g/cm3 Boiling Point 491.8±28.0 °C at 760 mmHg Molecular Formula C18H35NO3 Molecular Weight 313.48 Flash Point 251.2±24.0 °C Exact Mass 313.261688 PSA 66.40000 LogP 6.03 Appearance of Characters white to off-white Vapour Pressure 0.0±2.7 mmHg at 25°C Index of Refraction 1.468 InChIKey KVTFEOAKFFQCCX-UHFFFAOYSA-N SMILES CCCCCCCCCCCCCCCC(=O)NCC(=O)O Storage condition 2-8°C Water Solubility DMSO: >10mg/mL |
| Use of | Palmitoylglycine, a novel endogenous lipid, acts as a modulator of calcium influx and nitric oxide production in sensory neurons. Palmitoylglycine induces transient influx of calcium followed by nitric oxide production via calcium-sensitive nitric-oxide synthase enzymes. Palmitoylglycine potently inhibits heat-evoked firing of nociceptive neurons in rat dorsal horn[1]. Properties Articles13 Name 2-(hexadecanoylamino)acetic acid Synonym More Synonyms PALGLY Biological Activity Description Palmitoylglycine, a novel endogenous lipid, acts as a modulator of calcium influx and nitric oxide production in sensory neurons. Palmitoylglycine induces transient influx of calcium followed by nitric oxide production via calcium-sensitive nitric-oxide synthase enzymes. Palmitoylglycine potently inhibits heat-evoked firing of nociceptive neurons in rat dorsal horn[1]. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Signaling Pathways >> Immunology/Inflammation >> NO Synthase Research Areas >> Neurological Disease References [1]. Neta Rimmerman, et al. N-palmitoyl glycine, a novel endogenous lipid that acts as a modulator of calcium influx and nitric oxide production in sensory neurons. Mol Pharmacol. 2008 Jul;74(1):213-24. Chemical & Physical Properties Molecular Formula C18H35NO3 Exact Mass 313.261688 PSA 66.40000 Appearance of Characters white to off-white Index of Refraction 1.468 InChIKey KVTFEOAKFFQCCX-UHFFFAOYSA-N SMILES CCCCCCCCCCCCCCCC(=O)NCC(=O)O |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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