
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1290543-63-3 |
| Catalog No. | 2A-1194883 |
| Chinese Name | Nirogacestat |
| Synonyms | PF-3084014 |
| Molecular Formula | C27H41F2N5O |
| Molecular Weight | 489.64 (free base basis) |
| Purity | ≥98 (HPLC) |
| Appearance | powder |
| Storage Condition | -20℃ |
| Application | Nirogacestat (PF-3084014) is a reversible, non-competitive and selective γ-secretase inhibitor with an IC50 of 6.2 nM. |
| PubChem ID | 329823821 |
| SMILES | FC1=C2C(CC[C@H](N[C@@H](CCC)C(NC3=CN(C(C)(C)CNCC(C)(C)C)C=N3)=O)C2)=CC(F)=C1.C |
| InChI | 1S/C27H41F2N5O.CH4/c1-7-8-23(32-20-10-9-18-11-19(28)12-22(29)21(18)13-20)25(35)33-24-14-34(17-31-24)27(5,6)16-30-15-26(2,3)4;/h11-12,14,17,20,23,30,32H,7-10,13,15-16H2,1-6H3,(H,33,35);1H4/t20-,23-;/m0./s1 |
| InChI Key | GLEYBLZDOTUZJH-WCRWPNQISA-N |
| NACRES Code | NA.77 |
| UNSPSC | 51111800 |
| MSDS | msds/196551_1_1290543_63_3.pdf |
| Transport Info | Product name: PF-3084014 |
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| PVM/MA | 1644545-52-7 | 2A-1194876 |
| PKR-IN-2 | 1628428-01-2 | 2A-1194877 |
| TG6-10-1 | 1415716-58-3 | 2A-1194880 |
| WS3 | 1421227-52-2 | 2A-1194881 |
| hoi-07 | 1606160-40-0 | 2A-1194882 |
| Sodium ferrous citrate | 43160-25-4 | 2A-2194865 |
| Zinc lactate | 6155-68-6 | 2A-2194884 |
| 4-[3-hydroxy-3-phenyl-3-(2-thienyl)propyl]-4-methylmorpholinium methyl sulphate | 6504-57-0 | 2A-2194890 |
| IDIC | 1883441-92-6 | 2A-1194894 |
| IDT-C6 | 1509939-03-0 | 2A-1194906 |
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