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Home > Products > Pharmaceuticals & Life Science > Pharmaceutical Intermediates > [(4R,5S)-4,5-Bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl][4-[3-(methylsulfonyl)propyl]-1-piperazinyl]methanone
[(4R,5S)-4,5-Bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl][4-[3-(methylsulfonyl)propyl]-1-piperazinyl]methanone structure, CAS 939981-39-2

[(4R,5S)-4,5-Bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl][4-[3-(methylsulfonyl)propyl]-1-piperazinyl]methanone

CAS Number939981-39-2

SynonymsCS-0330; RG7112; RG-7112

Molecular FormulaC38H48Cl2N4O4S

Molecular Weight727.78

Purity≥98 (HPLC)%

Density1.2±0.1 g/cm3

Boiling Point790.4±70.0 °C at 760 mmHg

Melting Point

Flash Point

Appearancepowder

EINECS

MSDSChineseEnglish

Symbol

Signal Word

Cat. No.: 2A-1194873 Purity: ≥98 (HPLC)%
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Quality Control of [ 939981-39-2 ] Purity: ≥98 (HPLC)% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number939981-39-2
Catalog No.2A-1194873
Chinese Name[(4R,5S)-4,5-双(4-氯苯基)-2-[4-(1,1-二甲基乙基)-2-乙氧基苯基]-4,5-二氢-4,5-二甲基-1H-咪唑-1-基][4-[3-(甲磺酰基)丙基]-1-哌嗪基]甲酮
SynonymsCS-0330; RG7112; RG-7112
Molecular FormulaC38H48Cl2N4O4S
Molecular Weight727.78
Purity≥98 (HPLC)
Density1.2±0.1 g/cm3
Boiling Point790.4±70.0 °C at 760 mmHg
Appearancepowder
Storage Condition-20℃
ApplicationRG7112 is the first clinically available orally available MDM-2/p53 inhibitor with a Kd value of 11 nM.
PubChem ID136952608
MDL NumberMFCD29905459
SMILES[S](=O)(=O)(CCCN1CCN(CC1)C(=O)N2[C@]([C@](N=C2c5c(cc(cc5)C(C)(C)C)OCC)(C)c4ccc(cc4)Cl)(C)c3ccc(cc3)Cl)C
InChI1S/C38H48Cl2N4O4S/c1-8-48-33-26-29(36(2,3)4)14-19-32(33)34-41-37(5,27-10-15-30(39)16-11-27)38(6,28-12-17-31(40)18-13-28)44(34)35(45)43-23-21-42(22-24-43)20-9-25-49(7,46)47/h10-19,26H,8-9,20-25H2,1-7H3/t37-,38+/m0/s1
InChI KeyQBGKPEROWUKSBK-QPPIDDCLSA-N
NACRES CodeNA.21
MSDSmsds/196541_1_939981_39_2.pdf
Transport InfoProduct name: RG7112
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