CAS Number3466-75-9
Synonyms2-Hydroxy-3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzo(a)quinolizine; 3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol; 3-isobutyl-9-methoxy-10-methoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinoline-2-ol; 2-Hydroxytetrabenazine; trans (2,3)-Dihydro Tetrabenazine
Molecular FormulaC19H29O3N1
Molecular Weight319.44
Density1.1±0.1 g/cm3
Boiling Point457.8±45.0 °C at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 3466-75-9 |
| Catalog No. | 2A-1193560 |
| Chinese Name | Dihydrotetrabenazine |
| Synonyms | 2-Hydroxy-3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzo(a)quinolizine; 3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol; 3-isobutyl-9-methoxy-10-methoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinoline-2-ol; 2-Hydroxytetrabenazine; trans (2,3)-Dihydro Tetrabenazine |
| Molecular Formula | C19H29O3N1 |
| Molecular Weight | 319.44 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 457.8±45.0 °C at 760 mmHg |
| HTC | 2933990090 |
| PubChem ID | 10240877 |
| MDL Number | MFCD20275194 |
| SMILES | COc1cc2c(cc1OC)C1CC(O)C(CC(C)C)CN1CC2 |
| InChI | InChI=1S/C19H29NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16-17,21H,5-7,10-11H2,1-4H3 |
| InChI Key | WEQLWGNDNRARGE-UHFFFAOYSA-N |
| MSDS | msds/195157_1_3466_75_9.pdf |
| Use of | Dihydrotetrabenazine (racemic) is an active metabolite of the vesicular monoamine transporter 2 (VMAT2) inhibitor tetrabenazine that is generated by hepatic carbonyl reductases. Dihydrotetrabenazine binds to mouse pons medulla, hypothalamus, and striatum and inhibits synaptic vesicular serotonin (5-HT) uptake. It also binds to human caudate nucleus, hippocampus, and substantia nigra pars compacta. Dihydrotetrabenazine stereoisomers bind to VMAT2 in rat striatum. Properties Name 9,10-dimethoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-ol Synonym More Synonyms Chemical & Physical Properties Molecular Formula C19H29NO3 Exact Mass 319.214752 PSA 41.93000 Index of Refraction 1.562 InChIKey WEQLWGNDNRARGE-UHFFFAOYSA-N Safety Information HS Code 2933990090 Precursor & DownStream Precursor 0 DownStream 1 CAS#:5220-98-4 (+)-9-O-DESMETH... |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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