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Home > Products > Pharmaceuticals & Life Science > Pharmaceutical Intermediates > 2-Propen-1-one, 1-[(3S)-4-[(7R)-7-[6-amino-4-methyl-3-(trifluoromethyl)-2-pyridinyl]-6-chloro-8-fluoro-2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]-4-quinazolinyl]-3-methyl-1-piperazinyl]-
2-Propen-1-one, 1-[(3S)-4-[(7R)-7-[6-amino-4-methyl-3-(trifluoromethyl)-2-pyridinyl]-6-chloro-8-fluoro-2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]-4-quinazolinyl]-3-methyl-1-piperazinyl]- structure, CAS 2417987-45-0

2-Propen-1-one, 1-[(3S)-4-[(7R)-7-[6-amino-4-methyl-3-(trifluoromethyl)-2-pyridinyl]-6-chloro-8-fluoro-2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]-4-quinazolinyl]-3-methyl-1-piperazinyl]-

CAS Number2417987-45-0

Synonyms

Molecular FormulaC29H32O2N7Cl1F4

Molecular Weight622.07

Purity

Density

Boiling Point

Melting Point

Flash Point

Appearance

EINECS

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Cat. No.: 2A-1193265 Purity:
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Quality Control of [ 2417987-45-0 ] SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number2417987-45-0
Catalog No.2A-1193265
Chinese NameGDC-6036
Molecular FormulaC29H32O2N7Cl1F4
Molecular Weight622.07
ApplicationGDC-6036 (compound 17a) is a potent K-Ras G12C inhibitor with IC50 less than 0.01μM. The EC50 of GDC-6036 in K-Ras G12C alkylated HCC1171 cells is 2 nM [1].
PubChem ID406112088
MDL NumberMFCD34603941
SMILESC=CC(=O)N1CCN(c2nc(OCC3CCCN3C)nc3c(F)c(-c4nc(N)cc(C)c4C(F)(F)F)c(Cl)cc23)C(C)C1
InChIInChI=1S/C29H32ClF4N7O2/c1-5-21(42)40-9-10-41(16(3)13-40)27-18-12-19(30)22(26-23(29(32,33)34)15(2)11-20(35)36-26)24(31)25(18)37-28(38-27)43-14-17-7-6-8-39(17)4/h5,11-12,16-17H,1,6-10,13-14H2,2-4H3,(H2,35,36)/t16-,17-/m0/s1
InChI KeyZRBPIAWWRPFDPY-IRXDYDNUSA-N
MSDSmsds/194840_1_2417987_45_0.pdf
Transport InfoProduct Name: Divarasib
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