| Chemical & Physical Properties | |
|---|---|
| CAS Number | 10578-79-7 |
| Catalog No. | 2A-1192152 |
| Chinese Name | N4-甲基胞苷 |
| Synonyms | Cytidine,N-methyl; 4-N-Methylcytidine; N4-Methyl-cytidin; N4-Methylcytidine |
| Molecular Formula | C10H15N3O5 |
| Molecular Weight | 257.25 |
| Density | 1.69g/cm3 |
| Boiling Point | 504.2ºC at 760mmHg |
| Storage Condition | 2-8°C |
| Application | N4-methylcytidine (Nsc518744) is a cytidine nucleoside analog. Cytidine analogues have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420) and have potential anti-metabolic |
| HTC | 2934999090 |
| PubChem ID | 10232043 |
| SMILES | CNc1ccn(C2OC(CO)C(O)C2O)c(=O)n1 |
| InChI | InChI=1S/C10H15N3O5/c1-11-6-2-3-13(10(17)12-6)9-8(16)7(15)5(4-14)18-9/h2-3,5,7-9,14-16H,4H2,1H3,(H,11,12,17) |
| InChI Key | LZCNWAXLJWBRJE-ZOQUXTDFSA-N |
| Use of | N4-Methylcytidine (Nsc518744) is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1]. Properties Name 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(methylamino)pyrimidin-2-one Synonym More Synonyms Cytidine, N-methyl Biological Activity Description N4-Methylcytidine (Nsc518744) is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1]. Related Catalog Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others References [1]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8. Chemical & Physical Properties Molecular Formula C10H15N3O5 Exact Mass 257.10100 PSA 116.84000 Index of Refraction 1.694 InChIKey LZCNWAXLJWBRJE-ZOQUXTDFSA-N Safety Information HS Code 2934999090 Synthetic Route 2',3',5... 111426-20-1 Cytidine, N-met... 10578-79-7 Literature: Mahto, Santosh K.; Chow, Christine S. Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 19 p. 8795 - 8800 N4-dimethylamin... 17331-14-5 Cytidine, N-met... 10578-79-7 Literature: Zhang, Jianxing; Chang, Hui-Min; Kane, Robert R. Synlett, 2001 , # 5 p. 643 - 645 Cytidine, N-met... 10578-79-7 Literature: Miah, Anwar; Reese, Colin B.; Song, Quanlai Nucleosides and Nucleotides, 1997 , vol. 16, # 1-2 p. 53 - 65 Precursor & DownStream Precursor 10 CAS#:111426-20-1 2',3',5'-tri-O-... CAS#:17331-14-5 N4-dimethylamin... CAS#:58-96-8 CAS#:1748-04-5 Uridine,2',3',5... DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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