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4-Azido Butyl amine structure, CAS 88192-20-5

4-Azido Butyl amine

CAS Number88192-20-5

Synonyms6-azidobutylamine; 4-Azido-1-butanamine; 1-amino-4-azidobutane; 4-azido-1-butylamine; 1-azido-4-aminobutane; 4-azido-butylamine; 1-Butanamine,4-azido

Molecular FormulaC4H10N4

Molecular Weight233.28

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Cat. No.: 2A-1192019 Purity:
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Chemical & Physical Properties
CAS Number88192-20-5
Catalog No.2A-1192019
Chinese Name4-叠氮基-1-丁胺
Synonyms6-azidobutylamine; 4-Azido-1-butanamine; 1-amino-4-azidobutane; 4-azido-1-butylamine; 1-azido-4-aminobutane; 4-azido-butylamine; 1-Butanamine,4-azido
Molecular FormulaC4H10N4
Molecular Weight233.28
Application4-Azidobutylamine is a PROTAC bridge and belongs to the alkyl chain class. 4-Azidobutylamine can be used to synthesize a range of PROTAC molecules. PROTAC molecules contain two different ligands conne
HTC2929909090
PubChem ID329815796
MDL NumberMFCD04115094
SMILES[N-]=[N+]=NCCCCN
InChIInChI=1S/C4H10N4/c5-3-1-2-4-7-8-6/h1-5H2
InChI KeyLFMZGBHJJNIRKH-UHFFFAOYSA-N
NACRES CodeNA.21
UNSPSC12352116
Bioactivity4-Azidobutylamine is a PROTAC linker, which refers to the alkyl chain composition. 4-Azidobutylamine can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. Related Catalog Research Areas >> Cancer References [1]. Schiedel M, et al. Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals). J Med Chem. 2018 Jan 25;61(2):482-491. [2]. Schiedel M, et al. Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals). J Med Chem. 2018 Jan 25;61(2):482-491. Chemical & Physical Properties Molecular Formula C4H10N4 Molecular Weight 114.14900 Exact Mass 114.09100 PSA 75.77000 LogP 1.18866 InChIKey LFMZGBHJJNIRKH-UHFFFAOYSA-N SMILES [N-]=[N+]=NCCCCN
Use of4-Azidobutylamine is a PROTAC linker, which refers to the alkyl chain composition. 4-Azidobutylamine can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. Properties Name 4-Azidobutan-1-amine Synonym More Synonyms 4-Azidobutylamine Biological Activity Description 4-Azidobutylamine is a PROTAC linker, which refers to the alkyl chain composition. 4-Azidobutylamine can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. Related Catalog Research Areas >> Cancer References [1]. Schiedel M, et al. Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals). J Med Chem. 2018 Jan 25;61(2):482-491. [2]. Schiedel M, et al. Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals). J Med Chem. 2018 Jan 25;61(2):482-491. Chemical & Physical Properties Molecular Formula C4H10N4 Exact Mass 114.09100 PSA 75.77000 LogP 1.18866 InChIKey LFMZGBHJJNIRKH-UHFFFAOYSA-N SMILES [N-]=[N+]=NCCCCN
Tax Rebate9.0%
SupervisionNone MFN tariff: 6.5% Ordinary tariff: 30.0%
Transport InfoProduct name: Summary 2929909090 other compounds with other nitrogen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
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