TAS-115 structure, CAS 1190836-34-0

TAS-115

CAS Number1190836-34-0

Synonyms4-(2-Fluoro-4-{[(phenylacetyl)carbamothioyl]amino}phenoxy)-7-methoxy-N-methyl-6-quinolinecarboxamide

Molecular FormulaC27H23O4N4S1F1

Molecular Weight518.57

Purity

Density1.4±0.1 g/cm3

Boiling Point

Melting Point

Flash Point

Appearance

EINECS

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Symbol

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Cat. No.: 2A-1191757 Purity:
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Quality Control of [ 1190836-34-0 ] SDS Specification MoL

Chemical & Physical Properties
CAS Number1190836-34-0
Catalog No.2A-1191757
Chinese NameTAS-115
Synonyms4-(2-Fluoro-4-{[(phenylacetyl)carbamothioyl]amino}phenoxy)-7-methoxy-N-methyl-6-quinolinecarboxamide
Molecular FormulaC27H23O4N4S1F1
Molecular Weight518.57
Density1.4±0.1 g/cm3
Storage Condition2-8℃
ApplicationTAS-115 is a potent VEGFR and c-Met/HGFR inhibitor that inhibits the activities of rVEGFR2 and rMET with IC50 values ​​of 30 and 32 nM, respectively.
PubChem ID85281428
MDL NumberMFCD28386203
SMILESCNC(=O)c1cc2c(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)ccnc2cc1OC
InChIInChI=1S/C27H23FN4O4S/c1-29-26(34)19-14-18-21(15-24(19)35-2)30-11-10-22(18)36-23-9-8-17(13-20(23)28)31-27(37)32-25(33)12-16-6-4-3-5-7-16/h3-11,13-15H,12H2,1-2H3,(H,29,34)(H2,31,32,33,37)
InChI KeyORRNXRYWGDUDOG-UHFFFAOYSA-N
Transport InfoProduct Name: Pamufetinib (TAS-115)
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