
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1190836-34-0 |
| Catalog No. | 2A-1191757 |
| Chinese Name | TAS-115 |
| Synonyms | 4-(2-Fluoro-4-{[(phenylacetyl)carbamothioyl]amino}phenoxy)-7-methoxy-N-methyl-6-quinolinecarboxamide |
| Molecular Formula | C27H23O4N4S1F1 |
| Molecular Weight | 518.57 |
| Density | 1.4±0.1 g/cm3 |
| Storage Condition | 2-8℃ |
| Application | TAS-115 is a potent VEGFR and c-Met/HGFR inhibitor that inhibits the activities of rVEGFR2 and rMET with IC50 values of 30 and 32 nM, respectively. |
| PubChem ID | 85281428 |
| MDL Number | MFCD28386203 |
| SMILES | CNC(=O)c1cc2c(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)ccnc2cc1OC |
| InChI | InChI=1S/C27H23FN4O4S/c1-29-26(34)19-14-18-21(15-24(19)35-2)30-11-10-22(18)36-23-9-8-17(13-20(23)28)31-27(37)32-25(33)12-16-6-4-3-5-7-16/h3-11,13-15H,12H2,1-2H3,(H,29,34)(H2,31,32,33,37) |
| InChI Key | ORRNXRYWGDUDOG-UHFFFAOYSA-N |
| Transport Info | Product Name: Pamufetinib (TAS-115) |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| 2-(CarboxyMethyl)-4,5-diMethoxybenzoic acid | 3809-00-5 | 2A-1191751 |
| Indotecan | 915303-09-2 | 2A-1191753 |
| LMP744 | 308246-52-8 | 2A-1191754 |
| 4-[(2,2-Dimethyl-4,6-dioxo-[1,3]dioxan-5-ylidenemethyl)-amino]-2-methoxy-benzoic acid methyl ester | 205448-64-2 | 2A-1191755 |
| TAS-115 Methanesulfonic acid salt | 1688673-09-7 | 2A-1191756 |
| TAK-659 (hydrochloride) | 1952251-28-3 | 2A-1191759 |
| 3-METHYLAMINO-1-(2-THIENYL)-1-PROPANOL | 116539-56-1 | 2A-1191760 |
| STATIL | 72702-95-5 | 2A-1191761 |
| 1-(3-MORPHOLIN-4-YLPHENYL)ETHANONE | 59695-23-7 | 2A-1191762 |
| 1H-Imidazol-2-amine, 4,5-dihydro-N-(5,6,7,8-tetrahydro-1-naphthalenyl)-, hydrochloride (1:) | 14008-86-7 | 2A-1191763 |
| Browse all Specialty Chemicals products » | ||
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