![4-((2-(((1R,2R)-2-hydroxycyclohexyl)aMino)benzo[d]thiazol-6-yl)oxy)-N-MethylpicolinaMide structure, CAS 953769-46-5](/structures/210000/193238_1_953769_46_5.png)
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 953769-46-5 |
| Catalog No. | 2A-1191731 |
| Chinese Name | BLZ945 |
| Synonyms | 4-[(2-{[(1R,2R)-2-Hydroxycyclohexyl]amino}-1,3-benzothiazol-6-yl)oxy]-N-methyl-2-pyridinecarboxamide; blz-945; unii-7w3v82oq0p; BLZ945 |
| Molecular Formula | C20H22O3N4S1 |
| Molecular Weight | 398.49 |
| Density | 1.4±0.1 g/cm3 |
| Appearance | powder |
| Storage Condition | -20℃ |
| Application | BLZ945 is a potent, selective and brain-penetrating CSF-1R inhibitor with an IC50 of 1 nM and 1000-fold selectivity over other receptor tyrosine kinase homologues. |
| PubChem ID | 96038332 |
| MDL Number | MFCD28142668 |
| SMILES | CNC(=O)c1cc(Oc2ccc3nc(NC4CCCCC4O)sc3c2)ccn1 |
| InChI | InChI=1S/C20H22N4O3S/c1-21-19(26)16-10-13(8-9-22-16)27-12-6-7-15-18(11-12)28-20(24-15)23-14-4-2-3-5-17(14)25/h6-11,14,17,25H,2-5H2,1H3,(H,21,26)(H,23,24)/t14-,17-/m1/s1 |
| InChI Key | ADZBMFGQQWPHMJ-RHSMWYFYSA-N |
| Transport Info | Product name: BLZ945 |
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