3,3',4'-Tri hydroxy flavone structure, CAS 6068-78-6

3,3',4'-Tri hydroxy flavone

CAS Number6068-78-6

Synonyms3',4'-dihydroxyflavonol; 3',4'-Dihydroxyflavonol; 3,3',4'-TRIHYDROXYFLAVONE; 3,3',4'-trihydroxyflavon; 2-(3,4-dihydroxy-phenyl)-3-hydroxy-chromen-4-one

Molecular FormulaC15H10O5

Molecular Weight270.24

Purity

Density1.579g/cm3

Boiling Point508.9ºC at 760 mmHg

Melting Point

Flash Point

Appearance

EINECS

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Cat. No.: 2A-1190666 Purity:
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Chemical & Physical Properties
CAS Number6068-78-6
Catalog No.2A-1190666
Chinese Name3,3',4'-三羟基黄酮
Synonyms3',4'-dihydroxyflavonol; 3',4'-Dihydroxyflavonol; 3,3',4'-TRIHYDROXYFLAVONE; 3,3',4'-trihydroxyflavon; 2-(3,4-dihydroxy-phenyl)-3-hydroxy-chromen-4-one
Molecular FormulaC15H10O5
Molecular Weight270.24
Density1.579g/cm3
Boiling Point508.9ºC at 760 mmHg
Application3',4'-Dihydroxyflavonol (DiOHF) is a potent antioxidant that reduces superoxide and improves NO function in the mesenteric arteries of diabetic rats.
HTC2914501900
PubChem ID329825363
MDL NumberMFCD00189455
SMILESO=c1c(O)c(-c2ccc(O)c(O)c2)oc2ccccc12
InChIInChI=1S/C15H10O5/c16-10-6-5-8(7-11(10)17)15-14(19)13(18)9-3-1-2-4-12(9)20-15/h1-7,16-17,19H
InChI KeyKPGMHZQXQVDYNT-UHFFFAOYSA-N
NACRES CodeNA.77
UNSPSC12352200
Hazard Symbolstransportation
Bioactivity3',4'-Dihydroxyflavonol (DiOHF) is an effective antioxidant, which reduces superoxide and improves nitric oxide (NO) function in diabetic rat mesenteric arteries[1]. Related Catalog Research Areas >> Cardiovascular Disease Signaling Pathways >> Immunology/Inflammation >> NO Synthase Research Areas >> Metabolic Disease In Vitro 3',4'-Dihydroxyflavonol (DiOHF) acutely preserves nitric oxide (NO) activity in the presence of elevated reactive oxygen species (ROS). DiOHF improves NO activity in diabetes by reducing Nox2-dependent superoxide production and preventing eNOS uncoupling to improve endothelial function[1]. 3',4'-Dihydroxyflavonol reduces vascular contraction through Ca²⁺ desensitization in permeabilized third-order branches of rat mesenteric arteries[2]. References [1]. Leo CH, et al. 3',4'-Dihydroxyflavonol reduces superoxide and improves nitric oxide function in diabetic rat mesenteric arteries. PLoS One. 2011;6(6):e20813. [2]. Kim HY, et al. 3',4'-Dihydroxyflavonol reduces vascular contraction through Ca²⁺ desensitization in permeabilized rat mesenteric artery. Naunyn Schmiedebergs Arch Pharmacol. 2012 Feb;385(2):191-202. Chemical & Physical Properties Density 1.579g/cm3 Boiling Point 508.9ºC at 760 mmHg Molecular Formula C15H10O5 Molecular Weight 270.24 Flash Point 198ºC Exact Mass 270.05300 PSA 90.90000 LogP 2.57680 Index of Refraction 1.747 InChIKey KPGMHZQXQVDYNT-UHFFFAOYSA-N SMILES O=c1c(O)c(-c2ccc(O)c(O)c2)oc2ccccc12
Use of3',4'-Dihydroxyflavonol (DiOHF) is an effective antioxidant, which reduces superoxide and improves nitric oxide (NO) function in diabetic rat mesenteric arteries[1]. Properties Name 2-(3,4-dihydroxyphenyl)-3-hydroxychromen-4-one Synonym More Synonyms 3',4'-Dihydroxyflavonol Biological Activity Description 3',4'-Dihydroxyflavonol (DiOHF) is an effective antioxidant, which reduces superoxide and improves nitric oxide (NO) function in diabetic rat mesenteric arteries[1]. Related Catalog Research Areas >> Cardiovascular Disease Signaling Pathways >> Immunology/Inflammation >> NO Synthase Research Areas >> Metabolic Disease In Vitro 3',4'-Dihydroxyflavonol (DiOHF) acutely preserves nitric oxide (NO) activity in the presence of elevated reactive oxygen species (ROS). DiOHF improves NO activity in diabetes by reducing Nox2-dependent superoxide production and preventing eNOS uncoupling to improve endothelial function[1]. 3',4'-Dihydroxyflavonol reduces vascular contraction through Ca²⁺ desensitization in permeabilized third-order branches of rat mesenteric arteries[2]. References [1]. Leo CH, et al. 3',4'-Dihydroxyflavonol reduces superoxide and improves nitric oxide function in diabetic rat mesenteric arteries. PLoS One. 2011;6(6):e20813. [2]. Kim HY, et al. 3',4'-Dihydroxyflavonol reduces vascular contraction through Ca²⁺ desensitization in permeabilized rat mesenteric artery. Naunyn Schmiedebergs Arch Pharmacol. 2012 Feb;385(2):191-202. Chemical & Physical Properties Molecular Formula C15H10O5 Exact Mass 270.05300 PSA 90.90000 LogP 2.57680 Index of Refraction 1.747 InChIKey KPGMHZQXQVDYNT-UHFFFAOYSA-N
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Transport InfoShipping Name: UN
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Dangerous Regulations for land transport: 2811 International Dangerous Regulations for sea transport: 2811 International Dangerous Regulations for air transport: 2811 14.2 United Nations shipping name European Land Transport Dangerous Regulations: TOXIC SOLID, ORGANIC, N.O.S. (3', 4'-Dihydroxyflavonol) IMDG: TOXIC SOLID, ORGANIC, N.O.S. (3', 4'-Dihydroxyflavonol) International air transport hazard regulations: Toxic solid, organic, n.o.s. (3', 4'-Dihydroxyflavonol) 14.3 Transport hazard categories European Land Transport Danger Regulations: 6.1 International Maritime Transport Danger Regulations: 6.1 International Air Transport Danger Regulations: 6.1 14.4 Package group European Land Transport Danger Regulations: III International Maritime Transport Danger Regulations: III International Air Transport Danger Regulations: III 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available
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