EN
0
Home > Products > Specialty & Industrial Chemicals > Specialty Chemicals > N-Arachidonoylserotonin
N-Arachidonoylserotonin structure, CAS 187947-37-1

N-Arachidonoylserotonin

CAS Number187947-37-1

Synonyms(5Z,8Z,11Z,14Z)-N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-5,8,11,14-icosatetraenamide; Arachidonoyl serotonin; AA-5-HT N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenamide; (5Z,8Z,11Z,14Z)-N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]icosa-5,8,11,14-tetraenamide; Arachidonyl serotonin,N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-5,8,11,14-eicosatetraenamide; Arachidonyl serotonin; N-Arachidonoylserotonin

Molecular FormulaC30H42N2O2

Molecular Weight462.667

Purity

Density1.0±0.1 g/cm3

Boiling Point680.5±55.0 °C at 760 mmHg

Melting Point

Flash Point

Appearance

EINECS

MSDSChineseEnglish

Symboltransportation

Signal WordWarning

Cat. No.: 2A-1190408 Purity:
Change View

Please Login or Create an Account to: See VlP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

Inquiry

Quality Control of [ 187947-37-1 ] SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number187947-37-1
Catalog No.2A-1190408
Chinese NameArachidonoyl Serotonin
Synonyms(5Z,8Z,11Z,14Z)-N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-5,8,11,14-icosatetraenamide; Arachidonoyl serotonin; AA-5-HT N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenamide; (5Z,8Z,11Z,14Z)-N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]icosa-5,8,11,14-tetraenamide; Arachidonyl serotonin,N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-5,8,11,14-eicosatetraenamide; Arachidonyl serotonin; N-Arachidonoylserotonin
Molecular FormulaC30H42N2O2
Molecular Weight462.667
Density1.0±0.1 g/cm3
Boiling Point680.5±55.0 °C at 760 mmHg
Storage Condition-20°C, sealed, dry
ApplicationN-arachidonolase (arachidonyl serotonin; AA-5-HT) is a potent fatty acid amide hydrolase (FAAH) inhibitor with an IC50 value of 1 to 12 µM. Arachidonolase can also be used as an antagonist of transien
SMILESCCCCCC=CCC=CCC=CCC=CCCCC(=O)NCCc1c[nH]c2ccc(O)cc12
InChIInChI=1S/C30H42N2O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-30(34)31-23-22-26-25-32-29-21-20-27(33)24-28(26)29/h6-7,9-10,12-13,15-16,20-21,24-25,32-33H,2-5,8,11,14,17-19,22-23H2,1H3,(H,31,34)/b7-6-,10-9-,13-12-,16-15-
InChI KeyQJDNHGXNNRLIGA-DOFZRALJSA-N
Hazard Symbolstransportation
BioactivityN-Arachidonoylserotonin (Arachidonyl serotonin; AA-5-HT) is a potent fatty acid amide hydrolase (FAAH) inhibitor with an IC50 value of 1~12 µM. N-Arachidonoylserotonin acts also as an antagonist of transient receptor potential vanilloid-type 1 (TRPV1) channels (IC50=70~100 nM). N-Arachidonoylserotonin is analgesic in rodents [1]. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Signaling Pathways >> Metabolic Enzyme/Protease >> FAAH Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> FAAH Target IC50: 1~12 µM (FAAH), 70~100 nM (TRPV1 channels)[1] References [1]. Ortar G, et al. New N-arachidonoylserotonin analogues with potential "dual" mechanism of action against pain. J Med Chem. 2007;50(26):6554-6569. Chemical & Physical Properties Density 1.0±0.1 g/cm3 Boiling Point 680.5±55.0 °C at 760 mmHg Molecular Formula C30H42N2O2 Molecular Weight 462.667 Flash Point 365.3±31.5 °C Exact Mass 462.324615 PSA 65.12000 LogP 7.16 Vapour Pressure 0.0±2.2 mmHg at 25°C Index of Refraction 1.574 InChIKey QJDNHGXNNRLIGA-DOFZRALJSA-N SMILES CCCCCC=CCC=CCC=CCC=CCCCC(=O)NCCc1c[nH]c2ccc(O)cc12
Use ofN-Arachidonoylserotonin (Arachidonyl serotonin; AA-5-HT) is a potent fatty acid amide hydrolase (FAAH) inhibitor with an IC50 value of 1~12 µM. N-Arachidonoylserotonin acts also as an antagonist of transient receptor potential vanilloid-type 1 (TRPV1) channels (IC50=70~100 nM). N-Arachidonoylserotonin is analgesic in rodents [1]. Properties Name Arachidonoylserotonin Synonym More Synonyms Arachidonoyl serotonin Biological Activity Description N-Arachidonoylserotonin (Arachidonyl serotonin; AA-5-HT) is a potent fatty acid amide hydrolase (FAAH) inhibitor with an IC50 value of 1~12 µM. N-Arachidonoylserotonin acts also as an antagonist of transient receptor potential vanilloid-type 1 (TRPV1) channels (IC50=70~100 nM). N-Arachidonoylserotonin is analgesic in rodents [1]. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Signaling Pathways >> Metabolic Enzyme/Protease >> FAAH Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> FAAH References [1]. Ortar G, et al. New N-arachidonoylserotonin analogues with potential "dual" mechanism of action against pain. J Med Chem. 2007;50(26):6554-6569. Chemical & Physical Properties Molecular Formula C30H42N2O2 Exact Mass 462.324615 PSA 65.12000 Index of Refraction 1.574 InChIKey QJDNHGXNNRLIGA-DOFZRALJSA-N
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available See reverse side of invoice or packing slip.
Related Products in Specialty Chemicals
Benzene, 4-[4'-(3-butenyl)[1,1'-bicyclohexyl]-4-yl]-1,2-difluoro-, [trans(trans)]-155266-68-52A-1190404
1 Nω-methyl-5-hydroxytryptamine1134-01-62A-1190403
Coordination compounds of zinc(II) with L-5- hydroxytryptophan2A-11904052A-1190405
N-feruloylserotonin68573-23-92A-1190406
N-p(Coumaroyl)serotonin68573-24-02A-1190407
benzyl N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]carbamate53157-50-92A-1190409
hydrogen sulfate,2-(5-hydroxy-1H-indol-3-yl)ethylazanium2906-14-12A-1190410
[Cu(L-5-HTP)2Br2] ·H2O Coordination compounds of copper(II) with L-5-hydroxytryptophan2A-11904112A-1190411
p-hydroxyphenyl methacrylate31480-93-02A-1190412
3-(2-aminoethy)-1-methylindol-5-ol picrate1105-64-22A-1190412
Browse all Specialty Chemicals products »
Contact Us

Phone:

630-322-8886

630-322-8887

Email:

[email protected]

Office Locations:

Chicago, IL, USA

San Francisco, CA, USA