| Chemical & Physical Properties | |
|---|---|
| CAS Number | 13146-72-0 |
| Catalog No. | 2A-2189499 |
| Chinese Name | 9-((2R,3R,5S)-3-羟基-5-(羟甲基)四氢呋喃-2-基)-9H-嘌呤-6-醇 |
| Synonyms | 3'-Deoxyinosine; 9-((2R,3R,5S)-3-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol |
| Molecular Formula | C10H12O4N4 |
| Molecular Weight | 252.23 |
| Density | 1.9±0.1 g/cm3 |
| Boiling Point | 681.2±65.0 °C at 760 mmHg |
| Storage Condition | 2-8°C, sealed, dry, inert gas |
| Application | 3'-Deoxyinosine is a purine nucleoside analog. Purine nucleoside analogues have broad antitumor activity and target indolent lymphoid malignancies. The anti-cancer mechanism in this process relies on |
| HTC | 2934999090 |
| PubChem ID | 15069867 |
| MDL Number | MFCD28101744 |
| SMILES | OC[C@@H]1C[C@@H](O)[C@@H](O1)n2cnc3C(=O)N=CNc23 |
| InChI | InChI=1S/C10H12N4O4/c15-2-5-1-6(16)10(18-5)14-4-13-7-8(14)11-3-12-9(7)17/h3-6,10,15-16H,1-2H2,(H,11,12,17)/t5-,6+,10+/m0/s1 |
| InChI Key | InChIKey=RPZDLTVHZJHPAW-BAJZRUMYSA-N |
| Use of | 3'-Deoxyinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Properties Name 3′-deoxyinosine Synonym More Synonyms 3'-Deoxyinosine Biological Activity Description 3'-Deoxyinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog References [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. Chemical & Physical Properties Molecular Formula C10H12N4O4 Exact Mass 252.085861 PSA 113.26000 LogP -1.32 Index of Refraction 1.837 Safety Information Hazard Codes Xi HS Code 2934999090 Synthetic Route Total: 1 Page 2′,3′-Anhydroad... CAS#:2627-64-7 3'-Deoxyinosine CAS#:13146-72-0 Literature: Vodnala, Suman K.; Lundbaeck, Thomas; Yeheskieli, Esther; Sjoeberg, Birger; Gustavsson, Anna-Lena; Svensson, Richard; Olivera, Gabriela C.; Eze, Anthonius A.; De Koning, Harry P.; Hammarstroem, Lars G. J.; Rottenberg, Martin E. Journal of Medicinal Chemistry, 2013 , vol. 56, # 24 p. 9861 - 9873 Precursor & DownStream Precursor 1 CAS#:2627-64-7 2′,3′-Anhydroad... DownStream 1 CAS#:56220-55-4 1H-Imidazole-4-... |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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