| Chemical & Physical Properties | |
|---|---|
| CAS Number | 42794-76-3 |
| Catalog No. | 2A-2189373 |
| Chinese Name | 米多君 |
| Synonyms | 2-amino-N-(2-(2,5-dimethoxyphenyl)-2-hydroxyethyl)acetamide; MIDODRINE |
| Molecular Formula | C12H18N2O4 |
| Molecular Weight | 197.23 |
| Appearance | powder |
| Storage Condition | -20℃ |
| Application | Midodrine is an α1-receptor agonist for the treatment of familial dysautonomia and orthostatic hypotension. |
| HTC | 2924299090 |
| PubChem ID | 10092 |
| SMILES | COc1ccc(OC)c(C(O)CNC(=O)CN)c1 |
| InChI | InChI=1S/C12H18N2O4/c1-17-8-3-4-11(18-2)9(5-8)10(15)7-14-12(16)6-13/h3-5,10,15H,6-7,13H2,1-2H3,(H,14,16) |
| InChI Key | PTKSEFOSCHHMPD-UHFFFAOYSA-N |
| Use of | Midodrine is an α1-receptor agonist, for the treatment of dysautonomia and orthostatic hypotension. Properties Name midodrine Synonym More Synonyms Midodrine Biological Activity Description Midodrine is an α1-receptor agonist, for the treatment of dysautonomia and orthostatic hypotension. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease Chemical & Physical Properties Molecular Formula C12H18N2O4 Exact Mass 254.12700 PSA 93.81000 LogP 0.90330 InChIKey PTKSEFOSCHHMPD-UHFFFAOYSA-N Storage condition -20℃ Safety Information HS Code 2924299090 Synthetic Route Total: 1 Page N-(2-(2,5-Dimet... CAS#:176851-43-7 CAS#:42794-76-3 Literature: Caldwell, Nicola; Jamieson, Craig; Simpson, Iain; Tuttle, Tell Organic Letters, 2013 , vol. 15, # 10 p. 2506 - 2509 alpha-(Aminomet... CAS#:60407-53-6 CAS#:42794-76-3 Literature: Tsuda, Masahiro; Terada, Tomohiro; Irie, Megumi; Katsura, Toshiya; Niida, Ayumu; Tomita, Kenji; Fujii, Nobutaka; Inui, Ken-Ichi Journal of Pharmacology and Experimental Therapeutics, 2006 , vol. 318, # 1 p. 455 - 460 Precursor & DownStream Precursor 1 CAS#:60407-53-6 alpha-(Aminomet... DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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