CAS Number108466-89-3
Synonyms2,2-Dimethyl-4-oxo-3,8,11-trioxa-5-azatridecan-13-oic acid; 8-tert-Butyloxycarbonylamino-3,6-dioxaoctanoic Acid; AmbotzBAA1466; Boc-AEEA; 2-[2-[2-(Boc-amino)ethoxy]ethoxy]acetic Acid
Molecular FormulaC11H21NO6
Molecular Weight263.29
Boiling Point630.4°C
Melting Point240°C
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 108466-89-3 |
| Catalog No. | 2A-2188808 |
| Chinese Name | 2-[2-(叔丁氧羰基氨基)乙氧基]乙氧基乙酸 |
| Synonyms | 2,2-Dimethyl-4-oxo-3,8,11-trioxa-5-azatridecan-13-oic acid; 8-tert-Butyloxycarbonylamino-3,6-dioxaoctanoic Acid; AmbotzBAA1466; Boc-AEEA; 2-[2-[2-(Boc-amino)ethoxy]ethoxy]acetic Acid |
| Molecular Formula | C11H21NO6 |
| Molecular Weight | 263.29 |
| Boiling Point | 630.4°C |
| Melting Point | 240°C |
| Storage Condition | 2-8°C |
| Application | Boc-NH-PEG2-CH2COOH is a PROTAC linker based on PEG synthesis, used to synthesize PROTAC. |
| HTC | 2934999090 |
| PubChem ID | 6946049 |
| MDL Number | MFCD17019374 |
| SMILES | CC(C)(C)OC(=O)NCCOCCOCC(=O)O |
| InChI | InChI=1S/C11H21NO6/c1-11(2,3)18-10(15)12-4-5-16-6-7-17-8-9(13)14/h4-8H2,1-3H3,(H,12,15)(H,13,14) |
| InChI Key | OMBVJVWVXRNDSL-UHFFFAOYSA-N |
| NACRES Code | NA.22 |
| UNSPSC | 51171641 |
| Use of | Properties Name 2-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]acetic acid Synonym More Synonyms Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker Alkyl/ether In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. References [1]. Zhou F, et al. Development of selective mono or dual PROTAC degrader probe of CDK isoforms. Eur J Med Chem. 2020 Feb 1;187:111952. Chemical & Physical Properties Molecular Formula C11H21NO6 Exact Mass 263.13700 PSA 97.58000 LogP 0.83330 InChIKey OMBVJVWVXRNDSL-UHFFFAOYSA-N SMILES CC(C)(C)OC(=O)NCCOCCOCC(=O)O Safety Information Hazard Codes Xi HS Code 2934999090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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