![1,6-Dioxaspiro[2.5]octane-5-acetic acid, 7-[(1E,3E)-5-[(2S,3S,5R,6R)-5-[[(2Z,4S)-4-(acetyloxy)-1-oxo-2-penten-1-yl]amino]tetrahydro-3,6-dimethyl-2H-pyran-2-yl]-3-methyl-1,3-pentadien-1-yl]-8-hydroxy-, (3R,5S,7R,8R)- structure, CAS 1426953-21-0](/structures/210000/189554_1_1426953_21_0.png)
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1426953-21-0 |
| Catalog No. | 2A-2188187 |
| Chinese Name | 泰兰斯他汀A |
| Molecular Formula | C28H41NO9 |
| Molecular Weight | 535.63 |
| Storage Condition | -20°C |
| Application | Thailanstatin A is a super-potent inhibitor of eukaryotic RNA splicing (IC50=650 nM). Thailanstatin A acts through non-covalent binding to the SF3b subunit of the U2 snRNA subcomplex of the spliceosom |
| MDL Number | C28H41NO9 |
| SMILES | CC(=O)OC(C)C=CC(=O)NC1CC(C)C(CC=C(C)C=CC2OC(CC(=O)O)CC3(CO3)C2O)OC1C |
| InChI Key | GJKQDOMCDFJANR-UQAZGURTSA-N |
| Transport Info | Product Name: Thailanstatin A |
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