
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 391611-36-2 |
| Catalog No. | 2A-2188177 |
| Chinese Name | Spliceostatin A |
| Molecular Formula | C28H43NO8 |
| Molecular Weight | 521.64300 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 683.2±55.0 °C at 760 mmHg |
| Application | Splicing inhibitor A is a methylated derivative of FR901464 (HY-16212) and is an effective anti-tumor drug. Splice arrestin A inhibits splicing and promotes pre-mRNA accumulation by binding to SF3B1. |
| PubChem ID | 15706345 |
| SMILES | COC1(C)CC2(CO2)C(O)C(C=CC(C)=CCC2OC(C)C(NC(=O)C=CC(C)OC(C)=O)CC2C)O1 |
| InChI | InChI=1S/C28H43NO8/c1-17(9-12-24-26(32)28(16-34-28)15-27(6,33-7)37-24)8-11-23-18(2)14-22(20(4)36-23)29-25(31)13-10-19(3)35-21(5)30/h8-10,12-13,18-20,22-24,26,32H,11,14-16H2,1-7H3,(H,29,31)/b12-9+,13-10-,17-8+/t18-,19-,20+,22+,23-,24+,26+,27-,28+/m0/s1 |
| InChI Key | XKSGIJNRMWHQIQ-TUNPHNBLSA-N |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| Lysine-specific Demethylase Inhibitor (1C) | 927019-63-4 | 2A-4188168 |
| Propargyl-PEG5-alcohol | 87450-10-0 | 2A-2188170 |
| 2-[2-(PROP-2-YNYLOXY)ETHOXY]ETHAN-1-OL | 7218-43-1 | 2A-2188172 |
| Terutroban | 165538-40-9 | 2A-4188174 |
| N-Me-L-Ala-maytansinol | 77668-69-0 | 2A-2188175 |
| CORONATINE | 62251-96-1 | 2A-2188178 |
| DM1-SMCC | 1228105-51-8 | 2A-2188179 |
| YASQLQIQPVIGKL-LDRSRTPNSA-N | 133120-89-5 | 2A-2188180 |
| Dxd | 1599440-33-1 | 2A-2188182 |
| N-Acetyl-Calicheamicin | 108212-76-6 | 2A-2188183 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA