| Chemical & Physical Properties | |
|---|---|
| CAS Number | 92451-01-9 |
| Catalog No. | 2A-2188143 |
| Chinese Name | 甲氧基聚乙二醇 5,000 乙酸 N-琥珀酰亚胺基酯 |
| Synonyms | (2,5-dioxopyrrolidin-1-yl) 2-(2-hydroxyethoxy)acetate,2-methoxyethanol |
| Molecular Formula | (C2H4O)nC7H9NO5 |
| Molecular Weight | 1000(Average) |
| Storage Condition | −20°C |
| Application | m-PEG-NHS ester (MW 1000) can be used to modify active molecules and improve their antigenicity and immunogenicity to help prepare injectable preparations. m-PEG-NHS ester modifies the serine protease |
| PubChem ID | 24888488 |
| MDL Number | MFCD01867746 |
| SMILES | COCCO.O=C(COCCO)ON1C(=O)CCC1=O |
| InChI | InChI=1S/C8H11NO6.C3H8O2/c10-3-4-14-5-8(13)15-9-6(11)1-2-7(9)12;1-5-3-2-4/h10H,1-5H2;4H,2-3H2,1H3 |
| InChI Key | NYXRHTOXAYVBMV-UHFFFAOYSA-N |
| NACRES Code | NA.21 |
| UNSPSC | 12352200 |
| Hazard Symbols | transportation |
| Bioactivity | m-PEG-NHS ester (MW 1000) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects. Related Catalog Research Areas >> Others References [1]. Jin M, et al. Preparation of pegylated lumbrokinase and an evaluation of its thrombolytic activity both in vitro and in vivo[J]. Acta Pharmaceutica Sinica B, 2013, 3(2): 123-129. Chemical & Physical Properties Molecular Formula (C2H4O)nC7H9NO5 Molecular Weight 1000(Average) Exact Mass 293.11100 PSA 122.60000 InChIKey NYXRHTOXAYVBMV-UHFFFAOYSA-N SMILES COCCO.O=C(COCCO)ON1C(=O)CCC1=O Storage condition −20°C |
| Use of | m-PEG-NHS ester (MW 1000) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects. Properties Name Methoxypolyethylene glycol 5,000 acetic acid N-succinimidyl ester Synonym More Synonyms m-PEG-NHS ester (MW 1000) Biological Activity Description m-PEG-NHS ester (MW 1000) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects. Related Catalog Research Areas >> Others References [1]. Jin M, et al. Preparation of pegylated lumbrokinase and an evaluation of its thrombolytic activity both in vitro and in vivo[J]. Acta Pharmaceutica Sinica B, 2013, 3(2): 123-129. Chemical & Physical Properties Molecular Formula (C2H4O)nC7H9NO5 Exact Mass 293.11100 PSA 122.60000 InChIKey NYXRHTOXAYVBMV-UHFFFAOYSA-N |
| Transport Info | Product name: Purity: 80.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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