| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1393466-87-9 |
| Catalog No. | 2A-2188080 |
| Chinese Name | PLX8394 |
| Synonyms | Target; References |
| Molecular Formula | C25H21O3N6S1F3 |
| Molecular Weight | 542.54 |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 786.8±70.0 °C at 760 mmHg |
| Appearance | powder |
| Storage Condition | -20℃ |
| Application | PLX8394 is a potent and selective Raf inhibitor with an IC50 value of approximately 5 nM for inhibiting BRAFV600E activity. |
| PubChem ID | 240601817 |
| MDL Number | MFCD29472263 |
| SMILES | O=C(c1c(F)ccc(NS(=O)(=O)N2CCC(F)C2)c1F)c1c[nH]c2ncc(-c3cnc(C4CC4)nc3)cc12 |
| InChI | InChI=1S/C25H21F3N6O3S/c26-16-5-6-34(12-16)38(36,37)33-20-4-3-19(27)21(22(20)28)23(35)18-11-32-25-17(18)7-14(8-31-25)15-9-29-24(30-10-15)13-1-2-13/h3-4,7-11,13,16,33H,1-2,5-6,12H2,(H,31,32)/t16-/m1/s1 |
| InChI Key | YYACLQUDUDXAPA-MRXNPFEDSA-N |
| Transport Info | Product name: PLX8394 |
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