CAS Number13957-31-8
SynonymsEINECS 237-735-3; 4-Thio-uridin; 4-Thio-D-uridine; MFCD00006538; 4-thio-uridine; 1-(β-D-Ribofuranosyl)-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone; Uridine,4-thio; thiouridine; 4-SH-Ur; THIOURIDINE,4; 4-thiouridine
Molecular FormulaC9H12N2O5S
Molecular Weight260.27
Density1.7±0.1 g/cm3
Melting Point139-140℃ (ethanol )
AppearanceLight yellow powder
EINECS237-735-3
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 13957-31-8 |
| Catalog No. | 2A-2188005 |
| Chinese Name | 4-巯基尿苷 |
| Synonyms | EINECS 237-735-3; 4-Thio-uridin; 4-Thio-D-uridine; MFCD00006538; 4-thio-uridine; 1-(β-D-Ribofuranosyl)-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone; Uridine,4-thio; thiouridine; 4-SH-Ur; THIOURIDINE,4; 4-thiouridine |
| Molecular Formula | C9H12N2O5S |
| Molecular Weight | 260.27 |
| Density | 1.7±0.1 g/cm3 |
| Melting Point | 139-140℃ (ethanol ) |
| Appearance | Light yellow powder |
| Storage Condition | −20°C |
| Application | 4-Thiocarbamide is a ribonucleoside analog widely used in RNA analysis and (m)RNA labeling. 4-Thiocarbamide inhibits rRNA synthesis and causes nucleolar stress response [1]. |
| EINECS | 237-735-3 |
| HTC | 2934999090 |
| PubChem ID | 24900212 |
| MDL Number | MFCD00006538 |
| SMILES | O=c1[nH]c(=S)ccn1C1OC(CO)C(O)C1O |
| InChI | InChI=1S/C9H12N2O5S/c12-3-4-6(13)7(14)8(16-4)11-2-1-5(17)10-9(11)15/h1-2,4,6-8,12-14H,3H2,(H,10,15,17)/t4-,6-,7-,8-/m1/s1 |
| InChI Key | ZLOIGESWDJYCTF-XVFCMESISA-N |
| NACRES Code | NA.51 |
| UNSPSC | 41106305 |
| Hazard Symbols | transportation |
| Bioactivity | 4-Thiouridine is a ribonucleoside analog, it is widely used in RNA analysis and (m)RNA labeling. 4-Thiouridine inhibits rRNA synthesis and causes a nucleolar stress response[1]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others In Vitro 4-thiouridine (0-10 μM) labels and purifies nascent rRNA without significantly affecting rRNA synthesis[1]. 4-thiouridine (≥50 μM) strongly inhibits production and processing of rRNA[1]. References [1]. Burger K, et al. 4-thiouridine inhibits rRNA synthesis and causes a nucleolar stress response. RNA Biol. 2013 Oct;10(10):1623-30. Chemical & Physical Properties Density 1.7±0.1 g/cm3 Melting Point 139-140℃ (ethanol ) Molecular Formula C9H12N2O5S Molecular Weight 260.267 Exact Mass 260.046692 PSA 139.80000 LogP -0.21 Index of Refraction 1.733 InChIKey ZLOIGESWDJYCTF-XVFCMESISA-N SMILES O=c1[nH]c(=S)ccn1C1OC(CO)C(O)C1O Storage condition −20°C |
| Use of | 4-Thiouridine is a ribonucleoside analog, it is widely used in RNA analysis and (m)RNA labeling. 4-Thiouridine inhibits rRNA synthesis and causes a nucleolar stress response[1]. Properties Articles41 Name 4-thiouridine Synonym More Synonyms 4-thiouridine Biological Activity Description 4-Thiouridine is a ribonucleoside analog, it is widely used in RNA analysis and (m)RNA labeling. 4-Thiouridine inhibits rRNA synthesis and causes a nucleolar stress response[1]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others In Vitro 4-thiouridine (0-10 μM) labels and purifies nascent rRNA without significantly affecting rRNA synthesis[1]. 4-thiouridine (≥50 μM) strongly inhibits production and processing of rRNA[1]. References [1]. Burger K, et al. 4-thiouridine inhibits rRNA synthesis and causes a nucleolar stress response. RNA Biol. 2013 Oct;10(10):1623-30. Chemical & Physical Properties Molecular Formula C9H12N2O5S Exact Mass 260.046692 PSA 139.80000 LogP -0.21 Index of Refraction 1.733 InChIKey ZLOIGESWDJYCTF-XVFCMESISA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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