| Chemical & Physical Properties | |
|---|---|
| CAS Number | 3258-07-9 |
| Catalog No. | 2A-2187993 |
| Chinese Name | α-尿苷 |
| Synonyms | 1-(a-D-ribofuranosyl)uracil; BB_NC-2234 |
| Molecular Formula | C9H12N2O6 |
| Molecular Weight | 244.2 |
| Storage Condition | 2-8°C, dry and sealed |
| Application | 1-(a-D-ribofuranosyl)uracil is a purine nucleoside analog. Purine nucleoside analogues have broad antitumor activity and target indolent lymphoid malignancies. The anti-cancer mechanism in this proces |
| HTC | 2934999090 |
| PubChem ID | 26696248 |
| SMILES | O=c1ccn(C2OC(CO)C(O)C2O)c(=O)[nH]1 |
| InChI | InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8+/m1/s1 |
| InChI Key | DRTQHJPVMGBUCF-JBBNEOJLSA-N |
| Use of | 1-(a-D-ribofuranosyl)uracil is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Properties Name 1-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione Synonym More Synonyms 1-(A-D-RIBOFURANOSYL)URACIL Biological Activity Description 1-(a-D-ribofuranosyl)uracil is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog References [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. Chemical & Physical Properties Molecular Formula C9H12N2O6 Exact Mass 244.07000 PSA 125.04000 InChIKey DRTQHJPVMGBUCF-JBBNEOJLSA-N Safety Information HS Code 2934999090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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