CAS Number2752-17-2
Synonyms2,2'-Oxydiethanamine; GXVUZYLYWKWJIM-UHFFFAOYSA; diamino-PEG; EINECS 220-395-5; 2,2'-Oxydiethylamine; Bis(2-aminoethyl) Ether; 2,2′-Oxybis(ethylamine); 2,2-Oxybis(ethylamine); 1,5-diamino-3-oxa-pentane; 2,2'-Oxybis(ethylamine); 2,2'-Oxybis(ethylamine); 2-(2-Aminoethoxy)ethylamine; 2-aminoethyl ether; Ethanamine,2,2'-oxybis; 2,2'-Diaminodiethyl Ether; 2,2'-DITHIOBISBENZOIC ACID
Molecular FormulaC4H12O1N2
Molecular Weight104.15
Density1.0±0.1 g/cm3
Boiling Point185.9±15.0 °C at 760 mmHg
AppearanceTransparent colorless liquid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 2752-17-2 |
| Catalog No. | 2A-2187607 |
| Chinese Name | 2,2'-氧双(乙胺) |
| Synonyms | 2,2'-Oxydiethanamine; GXVUZYLYWKWJIM-UHFFFAOYSA; diamino-PEG; EINECS 220-395-5; 2,2'-Oxydiethylamine; Bis(2-aminoethyl) Ether; 2,2′-Oxybis(ethylamine); 2,2-Oxybis(ethylamine); 1,5-diamino-3-oxa-pentane; 2,2'-Oxybis(ethylamine); 2,2'-Oxybis(ethylamine); 2-(2-Aminoethoxy)ethylamine; 2-aminoethyl ether; Ethanamine,2,2'-oxybis; 2,2'-Diaminodiethyl Ether; 2,2'-DITHIOBISBENZOIC ACID |
| Molecular Formula | C4H12O1N2 |
| Molecular Weight | 104.15 |
| Density | 1.0±0.1 g/cm3 |
| Boiling Point | 185.9±15.0 °C at 760 mmHg |
| Appearance | Transparent colorless liquid |
| Storage Condition | Sealed in a cool, dry environment |
| Packaging | III |
| Application | 22-Oxybis(ethylamine) is a PROTAC linker, belonging to the PEG class. Can be used to synthesize PROTAC molecules. |
| HTC | 2922199090 |
| PubChem ID | 3137237 |
| MDL Number | MFCD00466591 |
| SMILES | NCCOCCN |
| InChI | InChI=1S/C4H12N2O/c5-1-3-7-4-2-6/h1-6H2 |
| InChI Key | GXVUZYLYWKWJIM-UHFFFAOYSA-N |
| Hazard Symbols | 8.0 |
| Bioactivity | 22-Oxybis(ethylamine) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker Target PEGs In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Chemical & Physical Properties Density 1.0±0.1 g/cm3 Boiling Point 185.9±15.0 °C at 760 mmHg Molecular Formula C4H12N2O Molecular Weight 104.151 Flash Point 74.8±14.1 °C Exact Mass 104.094963 PSA 61.27000 LogP -1.23 Vapour Pressure 0.7±0.4 mmHg at 25°C Index of Refraction 1.455 InChIKey GXVUZYLYWKWJIM-UHFFFAOYSA-N SMILES NCCOCCN |
| Use of | 22-Oxybis(ethylamine) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Properties Name 2-(2-aminoethoxy)ethanamine Synonym More Synonyms 2,2-Oxybis(ethylamine) Biological Activity Description 22-Oxybis(ethylamine) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Chemical & Physical Properties Molecular Formula C4H12N2O Exact Mass 104.094963 PSA 61.27000 LogP -1.23 Index of Refraction 1.455 InChIKey GXVUZYLYWKWJIM-UHFFFAOYSA-N SMILES NCCOCCN |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: Class 8 Corrosives UN number: 2735 Proper Shipping Name: Amine, Liquid, Corrosive, Not Otherwise Specified Packing grade: III |
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