![3-Pyridazinecarboxamide, N-[trans-4-(3-chloro-4-cyanophenoxy)cyclohexyl]-6-[4-[[4-[2-(2,6-dioxo-3-piperidinyl)-6-fluoro-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-1-piperazinyl]methyl]-1-piperidinyl]- structure, CAS 2222112-77-6](/structures/210000/188887_1_2222112_77_6.png)
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 2222112-77-6 |
| Catalog No. | 2A-2187537 |
| Chinese Name | N-[反式-4-(3-氯-4-氰基苯氧基)环己基]-6-[4-[[4-[2-(2,6-二氧-3-哌啶基)-6-氟] -2,3-二氢-1,3-二氧-1H-异吲哚-5-基]-1-哌嗪基]甲基]-1-哌啶基 |
| Molecular Formula | C41H43ClFN9O6 |
| Molecular Weight | 1028.11 |
| Storage Condition | 2-8℃, inert gas storage |
| Application | ARV-110 is an orally active, specific androgen receptor (AR) PROTAC degrader. ARV-110 promotes ubiquitination and degradation of AR. ARV-110 may be used in prostate cancer research. |
| PubChem ID | 374670567 |
| InChI | InChI=1S/C41H43ClFN9O6/c42-31-19-28(4-1-25(31)22-44)58-27-5-2-26(3-6-27)45-38(54)33-7-9-36(48-47-33)51-13-11-24(12-14-51)23-49-15-17-50(18-16-49)35-21-30-29(20-32(35)43)40(56)52(41(30)57)34-8-10-37(53)46-39(34)55/h1,4,7,9,19-21,24,26-27,34H,2-3,5-6,8,10-18,23H2,(H,45,54)(H,46,53,55) |
| InChI Key | CLCTZVRHDOAUGJ-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| Transport Info | Product name: ARV-110 |
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